State Route 58 is a major east-west state highway in the U.S. state of California that runs across the Coast Ranges, the southern San Joaquin Valley, the Tehachapi Mountains, which border the southern Sierra Nevada, and the Mojave Desert. It runs between U.S. Route 101 near Santa Margarita and Interstate 15 in Barstow. It has junctions with Interstate 5 near Buttonwillow, State Route 99 in Bakersfield, State Route 202 in Tehachapi, State Route 14 near Mojave, and U.S. Route 395 at Kramer Junction. SR 58 also provides access to Edwards Air Force Base. At various points it is known as the Calf Canyon Highway, Carrisa Highway, Bakersfield-McKittrick Highway, Rosa Parks Highway, Rosedale Highway, Barstow-Bakersfield Highway, Bakersfield Tehachapi Highway, Kern County Korean War Veterans Memorial Highway, and Mojave-Barstow Highway.
State Route 138 is an east–west state highway in the U.S. state of California that generally follows the northern foothills of the San Gabriel Mountains and the western Mojave Desert. The scenic highway begins in the west at its junction with Interstate 5 located south of Gorman in the Sierra Pelona Mountains, continues eastward through the Antelope Valley and Cajon Pass, to its junction with State Route 18 in the east, located in the San Bernardino Mountains south of Crestline.
State Route 152 is a state highway that runs from east to west near the middle of the U.S. state of California from State Route 1 in Watsonville to State Route 99 southeast of Merced. Its western portion provides access to and from Interstate 5 toward Southern California for motorists in or near Gilroy and San Jose.
State Route 126 is a state highway in the U.S. state of California that serves Ventura and Los Angeles counties. The route runs from U.S. Route 101 in Ventura to Interstate 5 in Santa Clarita through the Santa Clara River Valley. The highway is an important connector highway in Ventura County, and serves as an alternate route into the Santa Clarita Valley, and the San Fernando Valley area of Los Angeles and the High Desert of Antelope Valley.
State Route 35, generally known as Skyline Boulevard for most of its length, is a mostly two-lane state highway in the U.S. state of California. It runs along the ridge of the Santa Cruz Mountains from the high point of State Route 17 near Lexington Reservoir in Santa Clara County to State Route 1 just south of Daly City in San Mateo County, where it crosses SR 1 and loops around Lake Merced to become Sloat Boulevard in San Francisco. SR 35 then continues along Sloat Boulevard until it reaches its terminus when it meets SR 1 again at 19th Avenue.
State Route 84 is a state highway in the U.S. state of California that consists of two unconnected segments, one in the San Francisco Bay Area and the other primarily in the Sacramento–San Joaquin River Delta area.
State Route 116 (SR 116) is a state highway in the U.S. state of California in Sonoma County. The route runs from SR 1 on the Pacific coast near Jenner to SR 121 south of Sonoma.
State Route 25 is a state highway in the U.S. state of California between State Route 198 in Monterey County and U.S. Route 101 in Santa Clara south of Gilroy. For most of its length, SR 25 runs through the center of San Benito County.
State Route 12 is a state highway in the U.S. state of California that travels in an east–west direction from State Route 116 in Sebastopol in Sonoma County to State Route 49 just north of San Andreas in Calaveras County. The route connects the Sonoma and Napa valleys with the Sacramento–San Joaquin River Delta and the Sierra Foothills. It is constructed to freeway standards from the Fulton Road/South Wright Road stoplight in Santa Rosa, to its partial interchange with Farmers Lane.
State Route 33 is a north–south state highway in the U.S. state of California. It runs north from U.S. Route 101 in Ventura through the Transverse Ranges and the western side of the San Joaquin Valley to Interstate 5 at a point east of Tracy. SR 33 replaced part of U.S. Route 399 in 1964 during the "great renumbering" of routes. In the unincorporated sections of Kern County it is known as the West Side Highway. In addition, the California Legislature designated the entire Kern County portion as the Petroleum Highway in 2004. The southernmost portion in Ventura is a freeway known as the Ojai Freeway, while it is known as the Maricopa Highway from Ojai to Maricopa.
State Route 150 is a state highway in the U.S. state of California. It runs from U.S. Route 101 near the Ventura/Santa Barbara County line to State Route 126 in Santa Paula, providing a connection to Lake Casitas and Ojai. It is a two-lane road. There were some one-lane bridges near the western end of the route, but these were rebuilt to be two-lane bridges after flooding in 2005.
State Route 146 is a state highway in the U.S. state of California in Monterey and San Benito Counties. The route serves as an entryway to Pinnacles National Park, located in the Gabilan Mountains, from both U.S. Route 101 in the Salinas Valley on the west and State Route 25 near Paicines on the east. The route is broken into two sections and cannot be used to completely pass through Pinnacles National Park.
State Route 192 is a state highway in the U.S. state of California. The route runs from State Route 154 near Santa Barbara to State Route 150 near the Santa Barbara–Ventura county line. The two-lane road is better known as Foothill Road, as the route runs parallel to the foothills of the Santa Ynez Mountains.
State Route 27, commonly known by its street name Topanga Canyon Boulevard, is a state highway in the U.S. state of California that runs from the Pacific Coast Highway at Topanga State Beach near Pacific Palisades, through the Topanga Canyon in Topanga, and continuing through Woodland Hills, Canoga Park, West Hills, and Chatsworth to the Ronald Reagan Freeway.
State Route 156 is a west to east state highway in the U.S. state of California, running from State Route 1 in Castroville to State Route 152 near Hollister. It serves as part of the primary route from the Monterey Peninsula to either the San Francisco Bay Area or the California Central Valley.
State Route 246 is a state highway in the U.S. state of California that runs from Lompoc east to Solvang and Santa Ynez, cutting through the Santa Ynez Valley and the Santa Barbara Wine Country. Its western terminus is at the western city limits of Lompoc, and its eastern terminus is at State Route 154 near Santa Ynez.
State Route 225 was a state highway in the U.S. state of California that was a loop route of U.S. Route 101 that served the beach areas of the Santa Barbara area. The route was originally defined in 1963. In 2014, control of the highway was transferred from the state to the city of Santa Barbara. As of 2023, however, the California State Legislature has neither deleted nor even amended the legal definition of SR 225 in the California Streets and Highways Code since 2011 when they authorized Caltrans to transfer control of the highway to the city.
State Route 166 is a state highway in the U.S. state of California. It connects the Central Coast to the southern San Joaquin Valley, running from State Route 1 in Guadalupe and through Santa Maria in Santa Barbara County to State Route 99 in Mettler in Kern County.
State Route 135 is a state highway in the U.S. state of California. It acts as a western bypass of U.S. Route 101 in northern Santa Barbara County that runs through the community of Los Alamos and the center of the city of Santa Maria.
State Route 198 is an east–west state highway in the U.S. state of California that runs from U.S. Route 101 south of King City to Sequoia National Park. It connects the California Central Coast to the mid–Central Valley through Hanford and Visalia, although the most developed portion is in the Central Valley itself. SR 198 intersects the major north–south routes in the Central Valley, including Interstate 5 (I-5), SR 33, and SR 99.
San Marcos Pass Road
US 101 near Los Olivos 
