State Route 140 is a state highway in the U.S. state of California, 102 miles (164 km) in length. It begins in the San Joaquin Valley at Interstate 5 near Gustine, and runs east into Sierra Nevada, terminating in Yosemite National Park.
State Route 38 is a mostly rural and scenic state highway in the U.S. state of California, connecting Interstate 10 in Redlands with State Route 18 in the Big Bear Lake area. It is one of the primary routes into the San Bernardino Mountains. Despite the orientation of its alignment, SR 38 is assigned in a west–east direction.
State Route 120 is a state highway in the central part of California, connecting the San Joaquin Valley with the Sierra Nevada, Yosemite National Park, and the Mono Lake area. Its western terminus is at Interstate 5 in Lathrop, and its eastern terminus at U.S. Route 6 in Benton. While the route is signed as a contiguous route through Yosemite, the portion inside the park is federally maintained and is not included in the state route logs. The portion at Tioga Pass at Yosemite's eastern boundary is the highest paved through road in the California State Route system. This part is not maintained in the winter and is usually closed during the winter season.
State Route 299 is an east–west state highway in the state of California that runs across the northern part of the state. At 305.777 miles (492.100 km), it is the third longest California state highway. Route 299 begins at US 101 at the northern edge of Arcata and continues in an easterly direction through to the Nevada state line. Between Arcata and Redding, Route 299 intersects with State Route 96, and is briefly co-signed with State Route 3. In Redding, it intersects with State Route 273, State Route 44, and Interstate 5. East of Redding, it intersects with State Route 89, and a section is co-signed with State Route 139 before reaching Alturas. It is then co-signed with U.S. Route 395 northeast of Alturas, and then runs east toward the border with Nevada. A ghost town, Vya, Nevada, can be reached via this route, which after the border becomes a dirt road, which was formerly Nevada State Route 8A. The segment of SR 299 between Arcata and Redding is the Trinity Scenic Byway, a National Forest Scenic Byway.
State Route 154 is a state highway in the U.S. state of California that runs from Los Olivos to Santa Barbara, crossing the San Marcos Pass in the Santa Ynez Mountains. Before U.S. Route 101 was built through the Gaviota Pass, SR 154 was the main throughway to Santa Barbara and the tri city area including use as a stagecoach route in early years. After being replaced by US 101 as the primary route between the Santa Ynez Valley and Santa Barbara, SR 154 now serves as a scenic bypass.
State Route 25 is a state highway in the U.S. state of California between State Route 198 in Monterey County and U.S. Route 101 in Santa Clara south of Gilroy. For most of its length, SR 25 runs through the center of San Benito County.
State Route 33 is a north–south state highway in the U.S. state of California. It runs north from U.S. Route 101 in Ventura through the Transverse Ranges and the western side of the San Joaquin Valley to Interstate 5 at a point east of Tracy. SR 33 replaced part of U.S. Route 399 in 1964 during the "great renumbering" of routes. In the unincorporated sections of Kern County it is known as the West Side Highway. In addition, the California Legislature designated the entire Kern County portion as the Petroleum Highway in 2004. The southernmost portion in Ventura is a freeway known as the Ojai Freeway, while it is known as the Maricopa Highway from Ojai to Maricopa.
State Route 20 is a state highway in the northern-central region of the state of California, running east–west north of Sacramento from the North Coast to the Sierra Nevada. Its west end is at SR 1 in Fort Bragg, from where it heads east past Clear Lake, Colusa, Yuba City, Marysville and Nevada City to I-80 near Emigrant Gap, where eastbound traffic can continue on other routes to Lake Tahoe or Nevada.
State Route 88, also known as the Carson Pass Highway, is a state highway in the U.S. state of California. It travels in an east–west direction from Stockton in the San Joaquin Valley, crossing the Sierra Nevada at Carson Pass, and ending at the Nevada state line, whereupon it becomes Nevada State Route 88, eventually terminating at U.S. Route 395.
State Route 89 is a state highway in the U.S. state of California that travels in the north–south direction, serving as a major thoroughfare for many mountain communities in the Sierra Nevada and the Cascade Range. It starts from U.S. Route 395 near Topaz Lake, winding its way up to the 8,314-foot (2,534 m) Monitor Pass, down to the Carson River, and up again over the 7,740-foot (2,359 m) Luther Pass. From that point on, the route generally loses elevation on its way past Lake Tahoe, through Tahoe and Plumas National Forests until Lake Almanor. For roughly nine miles the route is then a part of State Route 36. The route then ascends to the 5,753-foot (1,754 m) Morgan Summit. After it enters Lassen Volcanic National Park it continues to gain elevation until it reaches its highest point in an unnamed pass in the middle of Lassen Peak and Bumpass Mountain. The road then descends and heads northwest, finally terminating at Interstate 5 at the foot of Mount Shasta at around 3,600 feet (1,100 m).
State Route 28 is a state highway in the U.S. state of California that travels along the northern shore of Lake Tahoe, starting at Route 89 in Tahoe City and ending at the Nevada state border, whereupon it becomes Nevada State Route 28.
State Route 108 is a state highway in the U.S. state of California that runs from the Central Valley and across the Sierra Nevada via the Sonora Pass. It generally runs northeast from downtown Modesto near the SR 99/SR 132 interchange, to U.S. Route 395 near the Nevada state line. The route was once recommended to continue south of Modesto to Interstate 5, although today that portion exists as a county road. Parts of SR 108 are closed annually during the winter due to inclement weather along the summit.
State Route 62 is a state highway in the U.S. state of California that cuts across the Little San Bernardino Mountains in Riverside and San Bernardino counties. It runs from Interstate 10 near White Water to the Arizona state line, passing through the city of Twentynine Palms and along the northern boundary of the Joshua Tree National Park.
State Route 70 is a state highway in the U.S. state of California, connecting SR 99 north of Sacramento with U.S. Route 395 near Beckwourth Pass via the Feather River Canyon. Through the Feather River Canyon, from SR 149 to US 395, SR 70 is the Feather River Scenic Byway, a Forest Service Byway that parallels the ex-Western Pacific Railroad's Feather River Route.
State Route 121 is a state highway in the U.S. state of California. It runs through the Wine Country region of Sonoma and Napa counties. Its southern terminus is at State Route 37 at Sears Point, and its northern terminus is at State Route 128 near Lake Berryessa. SR 121 passes through the Carneros region of the southern Sonoma Valley and Napa Valley.
State Route 127 is a state highway in the U.S. state of California that connects Interstate 15 in Baker to Nevada State Route 373 at the Nevada state line, passing near the eastern boundary of Death Valley National Park. The entire length of the highway closely follows the central portion of the former Tonopah and Tidewater Railroad and loosely follows the Amargosa River.
State Route 168 is an east-west state highway in the U.S. state of California that is separated into two distinct segments by the Sierra Nevada mountains. The western segment runs from State Routes 41 and 180 in Fresno east to Huntington Lake along the western slope of the Sierra. The eastern segment connects Lake Sabrina in the Eastern Sierra to State Route 266 in the community of Oasis, just to the west of the Nevada border. The eastern segment of SR 168 also forms a concurrency with U.S. Route 395 between Bishop and Big Pine.
State Route 167 is a state highway in the U.S. state of California in Mono County. From U.S. Route 395, SR 167 runs along Pole Line Road north of Mono Lake eastward to the Nevada state line where it meets Nevada State Route 359. This road runs almost completely straight, and can be seen almost 15 miles (24 km) into the distance as a straight line.
U.S. Route 6 (US 6) is a transcontinental United States Numbered Highway, stretching from Bishop, California, in the west to Provincetown, Massachusetts, in the east. The California portion of US 6 lies in the eastern portion of the state from Bishop in the Owens Valley north to the Nevada state line in Mineral County. Prior to a 1964 Highway renumbering project US 6 extended to the Pacific Ocean in Long Beach, California, as part of the historic auto trail named the Grand Army of the Republic Highway.
U.S. Route 95 (US 95) is a United States Numbered Highway, stretching from the Mexican border in San Luis, Arizona to the Canadian border near Eastport, Idaho. The California portion of US 95 traverses through the far eastern edges of both Riverside and San Bernardino counties. US 95 serves Blythe and Needles and junctions with SR 62 at Vidal Junction.
SR 266 at Nevada state line towards Lida, NV 
SR 168 at Oasis 
SR 264 at Nevada state line towards Dyer, NV 
