State Route 58 is a major east-west state highway in the U.S. state of California that runs across the Coast Ranges, the southern San Joaquin Valley, the Tehachapi Mountains, which border the southern Sierra Nevada, and the Mojave Desert. It runs between U.S. Route 101 near Santa Margarita and Interstate 15 in Barstow. It has junctions with Interstate 5 near Buttonwillow, State Route 99 in Bakersfield, State Route 202 in Tehachapi, State Route 14 near Mojave, and U.S. Route 395 at Kramer Junction. SR 58 also provides access to Edwards Air Force Base. At various points it is known as the Calf Canyon Highway, Carrisa Highway, Bakersfield-McKittrick Highway, Rosa Parks Highway, Westside Parkway, Barstow-Bakersfield Highway, Bakersfield Tehachapi Highway, Kern County Korean War Veterans Memorial Highway, and Mojave-Barstow Highway.
State Route 113 is a north–south state highway in the U.S. state of California that runs from around 10 miles (16 km) in the Sacramento Valley west of Rio Vista at State Route 12 to State Route 99 in Tudor. It serves as one of two important connecting routes between Interstate 80 and Interstate 5, bypassing Sacramento to the east; the other being Interstate 505 to the west. Past the southern terminus are Collinsville and Birds Landing around the Suisun Bay marshes. Cities along the route include Dixon, Davis, and Woodland. It also shares a stretch of Interstate 80 between just outside UC Davis and Dixon. The section running from Dixon to Woodland is a controlled-access freeway; the remainder is a standard road of two to four lanes. The freeway section spanning from the I-80 interchange in Davis to Woodland is called the Vic Fazio Highway, after the former U.S. House representative of the Davis area, who is credited with obtaining the funding for the freeway upgrade of that section.
State Route 12 is a state highway in the U.S. state of California that travels in an east–west direction from State Route 116 in Sebastopol in Sonoma County to State Route 49 just north of San Andreas in Calaveras County. The route connects the Sonoma and Napa valleys with the Sacramento–San Joaquin River Delta and the Sierra Foothills. It is constructed to freeway standards from the Fulton Road/South Wright Road stoplight in Santa Rosa, to its partial interchange with Farmers Lane.
State Route 29 is a state highway in the U.S. state of California that travels from Interstate 80 in Vallejo north to State Route 20 in Upper Lake. It serves as the primary road through the Napa Valley, providing access to the Lake County region to the north and the rest of the San Francisco Bay Area to the south.
State Route 165 is a rural north–south state highway in the U.S. state of California. It runs in the San Joaquin Valley from Interstate 5 south of Los Banos to State Route 99 in Turlock.
State Route 89 is a state highway in the U.S. state of California that travels in the north–south direction, serving as a major thoroughfare for many mountain communities in the Sierra Nevada and the Cascade Range. It starts from U.S. Route 395 near Topaz Lake, winding its way up to the 8,314-foot (2,534 m) Monitor Pass, down to the Carson River, and up again over the 7,740-foot (2,359 m) Luther Pass. From that point on, the route generally loses elevation on its way past Lake Tahoe, through Tahoe and Plumas National Forests until Lake Almanor. For roughly nine miles the route is then a part of State Route 36. The route then ascends to the 5,753-foot (1,754 m) Morgan Summit. After it enters Lassen Volcanic National Park it continues to gain elevation until it reaches its highest point in an unnamed pass in the middle of Lassen Peak and Bumpass Mountain. The road then descends and heads northwest, finally terminating at Interstate 5 at the foot of Mount Shasta at around 3,600 feet (1,100 m).
State Route 96 is a state highway in the U.S. state of California that follows the Trinity and Klamath Rivers between State Route 299 in Willow Creek and Interstate 5 near Yreka in Northern California. For most of the route it goes through the Karuk Tribal Reservation, the Yurok Tribal Reservation, and the Hoopa Tribal Reservation. Over half of the length is the Bigfoot Scenic Byway, passing through "the region boasting the most sightings of Bigfoot of anywhere in the country" according to the National Forest Scenic Byway Program.
State Route 193 is a state highway in the U.S. state of California that runs through Placer and El Dorado counties. It begins as an east–west arterial road running from Lincoln to Newcastle, just west of Auburn. Then after concurrencies with Interstate 80 and State Route 49 through Auburn, SR 193 resumes heading eastward from Cool to Georgetown, then turning south to rejoin SR 49 just north of Placerville.
State Route 28 is a state highway in the U.S. state of California that travels along the northern shore of Lake Tahoe, starting at Route 89 in Tahoe City and ending at the Nevada state border, whereupon it becomes Nevada State Route 28.
State Route 32 is an east–west state highway in the U.S. State of California which is routed from Interstate 5 in Orland, across the Sacramento Valley and through Chico, through the northern Sierra Nevada, and ending at SR 36 and SR 89 in eastern Tehama County.
State Route 132 is a state highway in the U.S. state of California that connects the Central Valley with the Sierra Nevada foothills and the California Gold Country. Its western segment also connects the city of Modesto with the San Francisco Bay Area via I-580, although this route is discouraged due to it being a two-lane road between Modesto and Interstate 5. East of Modesto, the road climbs the foothills and eventually ends at SR 49 at Coulterville.
State Route 166 is a state highway in the U.S. state of California. It connects the Central Coast to the southern San Joaquin Valley, running from State Route 1 in Guadalupe and through Santa Maria in Santa Barbara County to State Route 99 in Mettler in Kern County.
State Route 45 is a state highway in the U.S. State of California that travels in a north–south direction in the Sacramento Valley from Route 113 in Knights Landing to Route 32 in Hamilton City.
State Route 127 is a state highway in the U.S. state of California that connects Interstate 15 in Baker to Nevada State Route 373 at the Nevada state line, passing near the eastern boundary of Death Valley National Park. The entire length of the highway closely follows the central portion of the former Tonopah and Tidewater Railroad and loosely follows the Amargosa River.
State Route 128 is a state highway in the U.S. state of California, connecting the Mendocino coast to the Sacramento Valley, through the state's Wine Country. It runs from State Route 1 near Albion to Interstate 505 in Winters.
State Route 182 is a state highway in the U.S. state of California in Mono County. The route connects U.S. Route 395 in Bridgeport to Nevada State Route 338 at the Nevada state line via the East Walker River valley.
State Route 263 is a state highway in the U.S. state of California in Siskiyou County, running parallel to Interstate 5 to the west. Route 263 connects State Route 3 near the north city limits of Yreka to State Route 96 eight miles (13 km) north. Although SR 263 was once part of U.S. Route 99, it is not signed as part Business Loop 5.
State Route 265 is a state highway in the U.S. state of California that is part of both Business Loop 5 and Weed Boulevard in the City of Weed in Siskiyou County. SR 265 runs from U.S. Route 97 to Interstate 5.
State Route 273 is a state highway in the U.S. state of California that serves as a business loop of Interstate 5 that travels directly through the downtown districts of Anderson and Redding in Shasta County.
U.S. Route 95 (US 95) is a United States Numbered Highway, stretching from the Mexican border in San Luis, Arizona to the Canadian border near Eastport, Idaho. The California portion of US 95 traverses through the far eastern edges of both Riverside and San Bernardino counties. US 95 serves Blythe and Needles and junctions with SR 62 at Vidal Junction.
I-80 / SR 89 in Truckee 
SR 28 at Kings Beach 
