Cephalosporin-C transaminase

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cephalosporin-C transaminase
Identifiers
EC no. 2.6.1.74
CAS no. 122096-91-7
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In enzymology, a cephalosporin-C transaminase (EC 2.6.1.74) is an enzyme that catalyzes the chemical reaction

(7R)-7-(5-carboxy-5-oxopentanoyl)aminocephalosporinate + D-glutamate cephalosporin C + 2-oxoglutarate

Thus, the two substrates of this enzyme are (7R)-7-(5-carboxy-5-oxopentanoyl)aminocephalosporinate and D-glutamate, whereas its two products are cephalosporin C and 2-oxoglutarate.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is cephalosporin-C:2-oxoglutarate aminotransferase. Other names in common use include cephalosporin C aminotransferase, and L-alanine:cephalosporin-C aminotransferase. This enzyme participates in penicillin and cephalosporin biosynthesis.

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References


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