Chad Mirkin | |
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Born | Phoenix, Arizona, U.S. | November 23, 1963
Alma mater | Dickinson College, Pennsylvania State University |
Awards | Lemelson-MIT Prize, 2009 Linus Pauling Award, 2013 Raymond and Beverly Sackler Prize in Convergence Research, 2015 Dan David Prize, 2016 Wilhelm Exner Medal, 2017 William H. Nichols Medal Award, 2017 Ira Remsen Award, 2018 Kabiller Prize, 2019 Perkin Medal, 2019 AAAS Philip Hauge Abelson Prize, 2020 King Faisal Prize, 2023 Kavli Prize, 2024 |
Scientific career | |
Fields | Chemistry, Materials science, and Nanotechnology |
Institutions | Northwestern University |
Notable students |
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External videos | |
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"Nanotechnology: Moving Beyond Small Thinking", Chad Mirkin, Air Force Office of Scientific Research (AFOSR) |
Chad Alexander Mirkin (born November 23, 1963) is an American chemist. He is the George B. Rathmann professor of chemistry, professor of medicine, professor of materials science and engineering, professor of biomedical engineering, and professor of chemical and biological engineering, and director of the International Institute for Nanotechnology and Center for Nanofabrication and Molecular Self-Assembly at Northwestern University. [2]
Mirkin is known for his development of nanoparticle-based biodetection schemes, the invention of dip-pen nanolithography (recognized by National Geographic as one of the top 100 scientific discoveries that changed the world), and contributions to supramolecular chemistry, nanoelectronics, and nanooptics. In 2010, he was listed as the most cited chemist in the world over the last decade in terms of total citations, the second highest most cited chemist [3] in terms of impact factor, [4] and the top most cited nanomedicine researcher. [5]
Mirkin was born November 23, 1963, in Phoenix, Arizona. [6] He received his B.S. degree from Dickinson College in 1986 and his PhD from Penn State University in 1989 under the direction of Professor Gregory L. Geoffroy. [2] [7] He was a NSF postdoctoral research fellow at Massachusetts Institute of Technology where he worked with Professor Mark S. Wrighton on microelectrode devices for electrocatalysis. [8] He became a professor at Northwestern University in 1991. [7]
The focus of Mirkin's research is on developing methods for controlling the architecture of molecules and materials on the 1 – 100 nm length scale and utilizing such structures in the development of analytical tools that can be used in the areas of chemical and biological sensing, lithography, catalysis, and optics. Mirkin has pioneered the use of DNA and nanoparticles as synthons in materials science and the development of nanoparticle-based biodiagnostics. [2] [7]
A common strategy used by Mirkin's group is the use of the unique properties of spherical nucleic acids (SNAs), spherical arrangements of nucleic acids with or without organic or inorganic nanoparticle cores, to enable the synthesis of novel materials and colloidal crystals, the development of high sensitivity probes for chemical and medical diagnostic purposes, and single-entity structures capable of intracellular gene regulation. His 1996 work with SNA-gold nanoparticle conjugates introduced the concept of a nanoparticle as an atom and nucleic acids as bonds, and it laid the ground work for the fields of colloidal crystal engineering with DNA and molecular diagnostics based upon well-defined nanoparticle and nanocrystal bioconjugates. SNAs are the cornerstone of Luminex's FDA-cleared Verigene system (now used in over half of the world's top hospitals), EMD Millipore's SmartFlare platform (licensed to AuraSense, Inc. and Holden Pharma), and seven drugs in human clinical trials. In addition, his inventions of DPN, Polymer Pen Lithography (PPL), and Beam Pen Lithography (BPL) are the basis for the TERA-fab M and E series commercial patterning tools, known as desktop fabs (TERA-print, LLC).
He has published over 900 manuscripts, with a Google Scholar H-index of 204, [9] and has over 1,200 patents and patent applications. [10]
Mirkin has been elected into all three branches of the National Academies of Sciences, Engineering, and Medicine, the 10th person so honored. [11] He has served on several editorial advisory boards, including ACS Nano, the Journal of the American Chemical Society and Angewandte Chemie. He is the founding editor of the nanotechnology journal Small, and he is an associate editor of the Journal of the American Chemical Society. [12] Mirkin is a co-founder of multiple companies, including NanoInk, [13] Nanosphere (acquired by Luminex for $83M in 2016 [14] ), Azul 3D, [15] TERA-print, [16] Exicure, [17] and Stoicheia. [18]
Information scientists at CAS, a division of the American Chemical Society, singled out Mirkin and his contributions to supramolecular chemistry and nanomaterials in an article about potential future winners of the Nobel Prize in Chemistry, saying that “Overall, Mirkin’s work set up the foundation of modern nanotechnology and development of related diagnostic, therapeutic, and material applications.” [19]
In addition to his academic and research work, Mirkin has been involved in shaping science policy decisions. From 2009 to 2017 Mirkin was appointed to President Barack Obama's President's Council of Advisors on Science and Technology (PCAST). [20] [21] He co-chaired the PCAST report titled, "Engage to Excel," focusing on teaching and engagement issues involving students who are in their first two years of undergraduate study at R-1, 2 and 4-year institutions, and community colleges. [22]
Armand Paul Alivisatos is a Greek-American etymologist, chemist and academic administrator who has served as the 14th president of the University of Chicago since September 2021. He is a pioneer in nanomaterials development and an authority on the fabrication of nanocrystals and their use in biomedical and renewable energy applications. He was ranked fifth among the world's top 100 chemists for the period 2000–2010 in the list released by Thomson Reuters.
Mostafa A. El-Sayed is an Egyptian-American physical chemist, nanoscience researcher, member of the National Academy of Sciences and US National Medal of Science laureate. He is known for the spectroscopy rule named after him, the El-Sayed rule.
George McClelland Whitesides is an American chemist and professor of chemistry at Harvard University. He is best known for his work in the areas of nuclear magnetic resonance spectroscopy, organometallic chemistry, molecular self-assembly, soft lithography, microfabrication, microfluidics, and nanotechnology. A prolific author and patent holder who has received many awards, he received the highest Hirsch index rating of all living chemists in 2011.
Thalappil Pradeep is an institute professor and professor of chemistry in the Department of Chemistry at the Indian Institute of Technology Madras. He is also the Deepak Parekh Chair Professor. In 2020 he received the Padma Shri award for his distinguished work in the field of Science and Technology. He has received the Nikkei Asia Prize (2020), The World Academy of Sciences (TWAS) prize (2018), and the Shanti Swarup Bhatnagar Prize for Science and Technology in 2008 by Council of Scientific and Industrial Research.
Amanda Susan Barnard is an Australian theoretical physicist working in predicting the real world behavior of nanoparticles using analytical models and supercomputer simulations and applied machine learning. Barnard is a pioneer in the thermodynamic cartography of nanomaterials, creating nanoscale phase diagrams relevant to different environmental conditions, and relating these to structure/property maps. Her current research involves developing and applying statistical methods and machine/deep learning in nanoscience and nanotechnology, and materials and molecular informatics. In 2014 she became the first person in the southern hemisphere, and the first woman, to win the Feynman Prize in Nanotechnology, which she won for her work on diamond nanoparticles.
Younan Xia is a Chinese-American chemist, materials scientist, and bioengineer. He is the Brock Family Chair and Georgia Research Alliance (GRA) Eminent Scholar in Nanomedicine in the Wallace H. Coulter Department of Biomedical Engineering, with joint appointments in the School of Chemistry & Biochemistry, the School of Chemical & Biomolecular Engineering, and Parker H. Petit Institute for Bioengineering & Bioscience at the Georgia Institute of Technology.
Taeghwan Hyeon is a South Korean chemist. He is SNU distinguished professor in the School of Chemical and Biological Engineering at Seoul National University, director of Center for Nanoparticle Research of Institute for Basic Science (IBS), and an associate editor of the Journal of the American Chemical Society.
Ayyappanpillai Ajayaghosh is a research scientist/academician in the domain of interdisciplinary chemistry, and the former Director of the National Institute for Interdisciplinary Science and Technology. He is known for his studies on supramolecular assemblies, organogels, photoresponsive materials, chemosensory and security materials systems and is an elected fellow of all the three major Indian science academies viz. the National Academy of Sciences, India, Indian National Science Academy and the Indian Academy of Sciences as well as The World Academy of Sciences. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards for his contributions to Chemical Sciences in 2007. He is the first chemist to receive the Infosys Science Prize for physical sciences, awarded by the Infosys Science Foundation. He received the TWAS Prize of The World Academy of Sciences in 2013 and the Goyal prize in 2019.
Nicholas A. Kotov is the Irving Langmuir Distinguished Professor of Chemical Sciences and Engineering at the University of Michigan in Ann Arbor, MI, USA. Prof. Nicholas Kotov demonstrated that the ability to self-organize into complex structures is the unifying property of all inorganic nanostructures. He has developed a family of bioinspired composite materials with a wide spectrum of properties that were previously unattainable in classical materials. These composite biomimetic materials are exemplified by his nacre-like ultrastrong yet transparent composites, enamel-like, stiff yet vibration-isolating composites, and cartilage-like membranes with both high strength and ion conductance.
Teri W. Odom is an American chemist and materials scientist. She is the chair of the chemistry department, the Joan Husting Madden and William H. Madden, Jr. Professor of Chemistry, and a professor of materials science and engineering at Northwestern University. She is affiliated with the university's International Institute for Nanotechnology, Chemistry of Life Processes Institute, Northwestern Initiative for Manufacturing Science and Innovation, Interdisciplinary Biological Sciences Graduate Program, and department of applied physics.
Paolo Samorì is an Italian physical chemist and Distinguished Professor (PRCE) at the Institut de Science et d'Ingénierie Supramoléculaires (ISIS) of the Université de Strasbourg (UNISTRA) & CNRS where he heads the Nanochemistry Laboratory and he has been institute director (2012-2023).
CatherineJ. Murphy is an American chemist and materials scientist, and is the Larry Faulkner Professor of Chemistry at the University of Illinois at Urbana-Champaign (UIUC). The first woman to serve as the head of the department of chemistry at UIUC, Murphy is known for her work on nanomaterials, specifically the seed-mediated synthesis of gold nanorods of controlled aspect ratio. She is a member of the American Association for the Advancement of Science, National Academy of Sciences, and the American Academy of Arts and Sciences in 2019.
The International Institute for Nanotechnology (IIN) was established by Northwestern University in 2000. It was the first institute of its kind in the United States and is one of the premier nanoscience research centers in the world. Today, the IIN represents and unites more than $1 billion in nanotechnology research, educational programs, and supporting infrastructure.
Eugenia Eduardovna Kumacheva is a University Professor and Distinguished Professor of Chemistry at the University of Toronto. Her research interests span across the fields of fundamental and applied polymers science, nanotechnology, microfluidics, and interface chemistry. She was awarded the L'Oréal-UNESCO Awards for Women in Science in 2008 "for the design and development of new materials with many applications including targeted drug delivery for cancer treatments and materials for high density optical data storage". In 2011, she published a book on the Microfluidic Reactors for Polymer Particles co-authored with Piotr Garstecki. She is Canadian Research Chair in Advanced Polymer Materials. She is Fellow of the Royal Society (FRS) and a Fellow of the Royal Society of Canada (FRSC).
Clifford P. Kubiak is an American inorganic chemist, currently a Distinguished Professor in Chemistry and Biochemistry and the Harold C. Urey Chair in Chemistry at the University of California, San Diego. Over the course of his career, Kubiak has published over 200 scientific articles. He has also received the American Chemical Society Award in Inorganic Chemistry, and is a Fellow of the American Academy of Arts and Sciences and American Chemical Society. In 2020 he was elected to the National Academy of Sciences.
Christy Lynn Haynes is a chemist at the University of Minnesota. She works at the interface of analytical, biological, and nanomaterials chemistry.
Jill Millstone is a professor of chemistry at the University of Pittsburgh. She works on metal-ligand chemistry in nanoparticle synthesis. She is the American Chemical Society Kavli Foundation Emerging Leader in Chemistry Lecturer for 2018.
Vicki H. Grassian is a distinguished professor in the department of chemistry and biochemistry at the University of California, San Diego. She also holds the distinguished chair in physical chemistry.
Nathan C. Gianneschi is the Jacob & Rosaline Cohn Professor of Chemistry, Materials Science & Engineering, and Biomedical Engineering at Northwestern University and the Associate Director for the International Institute for Nanotechnology. Gianneschi's lab takes an interdisciplinary approach to nanomaterials research, with a focus on multifunctional materials for biomedical applications, programmed interactions with biomolecules and cells, and basic research into nanoscale materials design, synthesis and characterization.
So-Jung Park 박소정(朴昭靜) is a professor of chemistry at Ewha Womans University, Republic of Korea. Her research considers the self-assembly of nanoparticles and functional molecules for biomedical and optoelectronic devices. She serves as Associate Editor of ACS Applied Materials & Interfaces and Nanoscale.
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