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Caenorhabditis elegans is a free-living transparent nematode about 1 mm in length that lives in temperate soil environments. It is the type species of its genus. The name is a blend of the Greek caeno- (recent), rhabditis (rod-like) and Latin elegans (elegant). In 1900, Maupas initially named it Rhabditides elegans. Osche placed it in the subgenus Caenorhabditis in 1952, and in 1955, Dougherty raised Caenorhabditis to the status of genus.
Sydney Brenner was a South African biologist. In 2002, he shared the Nobel Prize in Physiology or Medicine with H. Robert Horvitz and Sir John E. Sulston. Brenner made significant contributions to work on the genetic code, and other areas of molecular biology while working in the Medical Research Council (MRC) Laboratory of Molecular Biology in Cambridge, England. He established the roundworm Caenorhabditis elegans as a model organism for the investigation of developmental biology, and founded the Molecular Sciences Institute in Berkeley, California, United States.
Howard Robert Horvitz ForMemRS NAS AAA&S APS NAM is an American biologist best known for his research on the nematode worm Caenorhabditis elegans, for which he was awarded the 2002 Nobel Prize in Physiology or Medicine, together with Sydney Brenner and John E. Sulston, whose "seminal discoveries concerning the genetic regulation of organ development and programmed cell death" were "important for medical research and have shed new light on the pathogenesis of many diseases".
Sir John Edward Sulston was a British biologist and academic who won the Nobel Prize in Physiology or Medicine for his work on the cell lineage and genome of the worm Caenorhabditis elegans in 2002 with his colleagues Sydney Brenner and Robert Horvitz at the MRC Laboratory of Molecular Biology. He was a leader in human genome research and Chair of the Institute for Science, Ethics and Innovation at the University of Manchester. Sulston was in favour of science in the public interest, such as free public access of scientific information and against the patenting of genes and the privatisation of genetic technologies.
Caenorhabditis is a genus of nematodes which live in bacteria-rich environments like compost piles, decaying dead animals and rotting fruit. The name comes from Greek: caeno- ; rhabditis = rod-like. In 1900, Maupas initially named the species Rhabditis elegans, Osche placed it in the subgenus Caenorhabditis in 1952, and in 1955, Dougherty raised Caenorhabditis to the status of genus.
John Graham White is an Emeritus Professor of Anatomy and Molecular Biology at the University of Wisconsin–Madison. His research interests are in the biology of the model organism Caenorhabditis elegans and laser microscopy.
Most animal testing involves invertebrates, especially Drosophila melanogaster, a fruit fly, and Caenorhabditis elegans, a nematode. These animals offer scientists many advantages over vertebrates, including their short life cycle, simple anatomy and the ease with which large numbers of individuals may be studied. Invertebrates are often cost-effective, as thousands of flies or nematodes can be housed in a single room.
The nematodesroundworms or eelworms, constitute the phylum Nematoda. They are a diverse animal phylum inhabiting a broad range of environments. Most species are free-living, feeding on microorganisms, but there are many that are parasitic. The parasitic worms (helminths) are the cause of soil-transmitted helminthiases.
SmY ribonucleic acids are a family of small nuclear RNAs found in some species of nematode worms. They are thought to be involved in mRNA trans-splicing.
Chryseobacterium is a genus of Gram-negative bacteria. Chryseobacterium species are chemoorganotrophic, rod shape gram-negative bacteria. Chryseobacterium form typical yellow-orange color colonies due to flexirubin-type pigment. The genus contains more than 100 described species from diverse habitats, including freshwater sources, soil, marine fish, and human hosts.
Caenorhabditis remanei is a species of nematode found in North America and Europe, and likely lives throughout the temperate world. Several strains have been developed in the laboratory.
Jonathan Alan Hodgkin is a British biochemist, Professor of Genetics at the University of Oxford and an emeritus fellow of Keble College, Oxford.
Caenorhabditis japonica is a species of nematodes in the genus Caenorhabditis. Its genome was sequenced by the McDonnell Genome Institute at Washington University School of Medicine. This gonochoristic species is found in the 'Japonica' group, the sister clade to the 'Elegans' group, in the 'Elegans' supergroup.
Caenorhabditis elegans- microbe interactions are defined as any interaction that encompasses the association with microbes that temporarily or permanently live in or on the nematode C. elegans. The microbes can engage in a commensal, mutualistic or pathogenic interaction with the host. These include bacterial, viral, unicellular eukaryotic, and fungal interactions. In nature C. elegans harbours a diverse set of microbes. In contrast, C. elegans strains that are cultivated in laboratories for research purposes have lost the natural associated microbial communities and are commonly maintained on a single bacterial strain, Escherichia coli OP50. However, E. coli OP50 does not allow for reverse genetic screens because RNAi libraries have only been generated in strain HT115. This limits the ability to study bacterial effects on host phenotypes. The host microbe interactions of C. elegans are closely studied because of their orthologs in humans. Therefore, the better we understand the host interactions of C. elegans the better we can understand the host interactions within the human body.
Cooperia oncophora is one of the most common intestinal parasitic nematodes in cattle in temperate regions. Infections with C. oncophora may result in mild clinical symptoms, but can lead to weight loss and damage of the small intestine, especially when co-infections with other nematodes such as O. ostertagi occur. Infections are usually treated with broad-spectrum anthelmintics such as benzimidazole, but resistance to these drugs has developed in the last decades and is now very common. C. oncophora has a direct life cycle. Infective larvae are ingested by the host. The larvae grow to adults, which reproduce in the small intestines. Eggs are shed onto the pasture with the faeces, which leads to new infections. Co-infections with other gastro-intestinal nematodes such as O. ostertagi and H. contortus are common.
Cooperia is the scientific name of two genera of organisms and may refer to:
Caenorhabditis portoensis is a species of nematode in the genus Caenorhabditis. First wild isolate sample was found on a rotting apple in Portugal.
Cooperia is a genus of nematode from the Cooperiidae family that is one of the most common intestinal parasitic nematodes in cattle in temperate regions. Infections with Cooperia may result in mild clinical symptoms, but can lead to weight loss and damage of the small intestine, especially when co-infections with other nematodes such as Ostertagia ostertagi occur. Infections are usually treated with broad-spectrum anthelmintics such as benzimidazole, but resistance to these drugs has developed in the last decades and is now very common. Cooperia has a direct life cycle. Infective larvae are ingested by the host. The larvae grow to adults, which reproduce in the small intestines. Eggs are shed onto the pasture with the faeces, which leads to new infections. Co-infections with other gastro-intestinal nematodes such as O. ostertagi and Haemonchus contortus are common.
Paul W. Sternberg is an American biologist. He does research for WormBase on C. elegans, a model organism.
Cytochrome P450, family 13, also known as CYP13, is a nematoda cytochrome P450 monooxygenase family. The first gene identified in this family is the CYP13A1 from the Caenorhabditis elegans.
References
- 1 2 Page, Antony P.; Roberts, Mark; Félix, Marie-Anne; Pickard, Derek; Page, Andrew; Weir, William (28 February 2019). "The golden death bacillus Chryseobacterium nematophagum is a novel matrix digesting pathogen of nematodes". BMC Biology. 17 (10): 10. doi: 10.1186/s12915-019-0632-x . PMC 6394051 . PMID 30813925.
- ↑ Zhang, Sarah (28 February 2019). "The 'Golden Death' Bacterium Found in a Rotten Apple" . Retrieved 28 February 2019.