Gliding motility

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Gliding motility is a type of translocation used by microorganisms that is independent of propulsive structures such as flagella, pili, and fimbriae. [1] Gliding allows microorganisms to travel along the surface of low aqueous films. The mechanisms of this motility are only partially known.

Contents

Twitching motility also allows microorganisms to travel along a surface, but this type of movement is jerky and uses pili as its means of transport. Bacterial gliding is a type of gliding motility that can also use pili for propulsion.

The speed of gliding varies between organisms, and the reversal of direction is seemingly regulated by some sort of internal clock. [2] For example the apicomplexans are able to travel at fast rates between 1–10 μm/s. In contrast Myxococcus xanthus bacteria glide at a rate of 0.08 μm/s. [3] [4]

Types of gliding motility in bacteria:

a) type IV pili,  b) Specific motility membrane proteins,  c) Polysaccharide jet

see description below Gliding Motility.svg
Types of gliding motility in bacteria:

a)  type IV pili, b) Specific motility membrane proteins, c) Polysaccharide jet

Cell-invasion and gliding motility have TRAP (thrombospondin-related anonymous protein), a surface protein, as a common molecular basis that is both essential for infection and locomotion of the invasive apicomplexan parasite. [5] Micronemes are secretory organelles on the apical surface of the apicomplexans used for gliding motility.

In the diagram above, right:

a) type IV pili
A cell attaches its pili to a surface or object in the direction it is traveling. The proteins in the pili are then broken down to shrink the pili pulling the cell closer to the surface or object that was it was attached to. [6]
b)Specific motility membrane proteins
Transmembrane proteins are attached to the host surface. This adhesion complex can either be specific to a certain type of surface like a certain cell type or generic for any solid surface. Motor proteins attached to an inner membrane force the movement of the internal cell structures in relation to the transmembrane proteins creating net movement. [7] This is driven by the proton motive force. [8] The proteins involved differ between species. An example of a bacterium that uses this mechanism would be Flavobacterium. This mechanism is still being studied and is not well understood. [9]
c)Polysaccharide jet
The cell releases a 'jet' of polysaccharide material behind it propelling it forward. This polysaccharide material is left behind. [10]

Types of motility

Bacterial gliding is a process of motility whereby a bacterium can move under its own power. Generally, the process occurs whereby the bacterium moves along a surface in the general direction of its long axis. [11] Gliding may occur via distinctly different mechanisms, depending on the type of bacterium. This type of movement has been observed in phylogenetically diverse bacteria [12] such as cyanobacteria, myxobacteria, cytophaga, flavobacteria, and mycoplasma.

Bacteria move in response to varying climates, water content, presence of other organisms, and firmness of surfaces or media. Gliding has been observed in a wide variety of phyla, and though the mechanisms may vary between bacteria, it is currently understood that it takes place in environments with common characteristics, such as firmness and low-water, which enables the bacterium to still have motility in its surroundings. Such environments with low-water content include biofilms, soil or soil crumbs in tilth, and microbial mats. [11]

Purpose

Gliding, as a form of motility, appears to allow for interactions between bacteria, pathogenesis, and increased social behaviours. It may play an important role in biofilm formation, bacterial virulence, and chemosensing. [13]

Swarming motility

Swarming motility occurs on softer semi-solid and solid surfaces (which usually involves movement of a bacterial population in a coordinated fashion via quorum sensing, using flagella to propel them), or twitching motility [12] on solid surfaces (which involves extension and retraction of type IV pili to drag the bacterium forward). [14]

Proposed mechanisms

The mechanism of gliding might differ between species. Examples of such mechanisms include:

See also

Related Research Articles

<span class="mw-page-title-main">Pilus</span> A proteinaceous hair-like appendage on the surface of bacteria

A pilus is a hair-like appendage found on the surface of many bacteria and archaea. The terms pilus and fimbria can be used interchangeably, although some researchers reserve the term pilus for the appendage required for bacterial conjugation. All conjugative pili are primarily composed of pilin – fibrous proteins, which are oligomeric.

<span class="mw-page-title-main">Flagellum</span> Cellular appendage functioning as locomotive or sensory organelle

A flagellum is a hairlike appendage that protrudes from certain plant and animal sperm cells, from fungal spores (zoospores), and from a wide range of microorganisms to provide motility. Many protists with flagella are known as flagellates.

<i>Neisseria gonorrhoeae</i> Species of bacterium

Neisseria gonorrhoeae, also known as gonococcus (singular) or gonococci (plural), is a species of Gram-negative diplococci bacteria isolated by Albert Neisser in 1879. It causes the sexually transmitted genitourinary infection gonorrhea as well as other forms of gonococcal disease including disseminated gonococcemia, septic arthritis, and gonococcal ophthalmia neonatorum.

In biology, quorum sensing or quorum signaling (QS) is the process of cell-to-cell communication that allows bacteria to detect and respond to cell population density by gene regulation, typically as a means of acclimating to environmental disadvantages.

<span class="mw-page-title-main">Myxobacteria</span> Order of bacteria

The myxobacteria are a group of bacteria that predominantly live in the soil and feed on insoluble organic substances. The myxobacteria have very large genomes relative to other bacteria, e.g. 9–10 million nucleotides except for Anaeromyxobacter and Vulgatibacter. One species of myxobacteria, Minicystis rosea, has the largest known bacterial genome with over 16 million nucleotides. The second largest is another myxobacteria Sorangium cellulosum.

Adhesins are cell-surface components or appendages of bacteria that facilitate adhesion or adherence to other cells or to surfaces, usually in the host they are infecting or living in. Adhesins are a type of virulence factor.

Intracellular parasites are microparasites that are capable of growing and reproducing inside the cells of a host. They are also called intracellular pathogens.

<i>Myxococcus xanthus</i> Slime bacterium

Myxococcus xanthus is a gram-negative, bacillus species of myxobacteria that is typically found in the top-most layer of soil. These bacteria lack flagella; rather, they use pili for motility. M. xanthus is well-known for its predatory behavior on other microorganisms. These bacteria source carbon from lipids rather than sugars. They exhibit various forms of self-organizing behavior in response to environmental cues. Under normal conditions with abundant food, they exist as predatory, saprophytic single-species biofilm called a swarm, highlighting the importance of intercellular communication for these bacteria. Under starvation conditions, they undergo a multicellular development cycle.

<span class="mw-page-title-main">Bacteria</span> Domain of microorganisms

Bacteria are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among the first life forms to appear on Earth, and are present in most of its habitats. Bacteria inhabit soil, water, acidic hot springs, radioactive waste, and the deep biosphere of Earth's crust. Bacteria play a vital role in many stages of the nutrient cycle by recycling nutrients and the fixation of nitrogen from the atmosphere. The nutrient cycle includes the decomposition of dead bodies; bacteria are responsible for the putrefaction stage in this process. In the biological communities surrounding hydrothermal vents and cold seeps, extremophile bacteria provide the nutrients needed to sustain life by converting dissolved compounds, such as hydrogen sulphide and methane, to energy. Bacteria also live in mutualistic, commensal and parasitic relationships with plants and animals. Most bacteria have not been characterised and there are many species that cannot be grown in the laboratory. The study of bacteria is known as bacteriology, a branch of microbiology.

<span class="mw-page-title-main">Flavobacteriia</span> Class of bacteria

The class Flavobacteriia is composed of a single class of environmental bacteria. It contains the family Flavobacteriaceae, which is the largest family in the phylum Bacteroidota. This class is widely distributed in soil, fresh, and seawater habitats. The name is often spelt Flavobacteria, but was officially named Flavobacteriia in 2012.

<span class="mw-page-title-main">Bacterial motility</span> Ability of bacteria to move independently using metabolic energy

Bacterial motility is the ability of bacteria to move independently using metabolic energy. Most motility mechanisms that evolved among bacteria also evolved in parallel among the archaea. Most rod-shaped bacteria can move using their own power, which allows colonization of new environments and discovery of new resources for survival. Bacterial movement depends not only on the characteristics of the medium, but also on the use of different appendages to propel. Swarming and swimming movements are both powered by rotating flagella. Whereas swarming is a multicellular 2D movement over a surface and requires the presence of surfactants, swimming is movement of individual cells in liquid environments.

<i>Cytophaga</i> Genus of bacteria

Cytophaga is a genus of Gram-negative, gliding, rod-shaped bacteria. This bacterium is commonly found in soil, rapidly digests crystalline cellulose C. hutchinsonii is able to use its gliding motility to move quickly over surfaces. Although the mechanism for this is not known, there is a belief that the flagellum is not used

<i>Myxococcus</i> Genus of bacteria

Myxococcus is a genus of bacteria in the family Myxococcaceae. Myxococci are Gram-negative, spore-forming, chemoorganotrophic, obligate aerobes. They are elongated rods with rounded or tapered ends, and they are nonflagellated. The cells move by gliding and can predate other bacteria. The genus has been isolated from soil.

<span class="mw-page-title-main">Twitching motility</span> Form of crawling bacterial motility

Twitching motility is a form of crawling bacterial motility used to move over surfaces. Twitching is mediated by the activity of hair-like filaments called type IV pili which extend from the cell's exterior, bind to surrounding solid substrates, and retract, pulling the cell forwards in a manner similar to the action of a grappling hook. The name twitching motility is derived from the characteristic jerky and irregular motions of individual cells when viewed under the microscope. It has been observed in many bacterial species, but is most well studied in Pseudomonas aeruginosa, Neisseria gonorrhoeae and Myxococcus xanthus. Active movement mediated by the twitching system has been shown to be an important component of the pathogenic mechanisms of several species.

<span class="mw-page-title-main">Social motility</span>

Social motility describes the motile movement of groups of cells that communicate with each other to coordinate movement based on external stimuli. There are multiple varieties of each kingdom that express social motility that provides a unique evolutionary advantages that other species do not possess. This has made them lethal killers such as African trypanosomiasis, or Myxobacteria. These evolutionary advantages have proven to increase survival rate among socially motile bacteria whether it be the ability to evade predators or communication within a swarm to form spores for long term hibernation in times of low nutrients or toxic environments.

<span class="mw-page-title-main">Marine prokaryotes</span> Marine bacteria and marine archaea

Marine prokaryotes are marine bacteria and marine archaea. They are defined by their habitat as prokaryotes that live in marine environments, that is, in the saltwater of seas or oceans or the brackish water of coastal estuaries. All cellular life forms can be divided into prokaryotes and eukaryotes. Eukaryotes are organisms whose cells have a nucleus enclosed within membranes, whereas prokaryotes are the organisms that do not have a nucleus enclosed within a membrane. The three-domain system of classifying life adds another division: the prokaryotes are divided into two domains of life, the microscopic bacteria and the microscopic archaea, while everything else, the eukaryotes, become the third domain.

<span class="mw-page-title-main">Joshua Shaevitz</span> American biophysicist

Joshua Shaevitz is an American biophysicist and Professor of Physics at the Lewis-Sigler Institute at Princeton University in Princeton, NJ. He is known for his work in single-molecule biophysics, bacterial growth and motility, and animal behavior.

Cytophaga hutchinsonii is a bacterial species in the genus Cytophaga. C. hutchinsonii is an aerobic, gram-negative, soil, microorganism that exhibits gliding motility, enabling it to move quickly over surfaces and is capable of cellulose degradation.

<span class="mw-page-title-main">Cyanobacterial morphology</span> Form and structure of a phylum

Cyanobacterial morphology refers to the form or shape of cyanobacteria. Cyanobacteria are a large and diverse phylum of bacteria defined by their unique combination of pigments and their ability to perform oxygenic photosynthesis.

<span class="mw-page-title-main">Adventurous motility</span>

Adventurous motility is as a type of gliding motility; unlike most motility mechanisms, adventurous motility does not involve a flagellum. Gliding motility usually involves swarms of bacteria; however, adventurous motility is practiced by individual cells. This gliding is hypothesized to occur via assembly of a type IV secretion system and the extrusion of a polysaccharide slime, or by use of a series of adhesion complexes. The majority of research on adventurous motility has focused on the species, Myxococcus xanthus. The earliest of this research is attributed to Jonathan Hodgkin and Dale Kaiser.

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