Dalea humifusa

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Dalea humifusa
Scientific classification Red Pencil Icon.png
Kingdom: Plantae
Clade: Tracheophytes
Clade: Angiosperms
Clade: Eudicots
Clade: Rosids
Order: Fabales
Family: Fabaceae
Genus: Dalea
Species:
D. humifusa
Binomial name
Dalea humifusa

Dalea humifusa is a species of plant in the family Fabaceae. It is found only in Ecuador. Its natural habitat is subtropical or tropical dry shrubland.

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Pawhuskin A Chemical compound

Pawhuskin A is a naturally occurring prenylated stilbene isolated from Dalea purpurea which acts as a competitive silent antagonist of the κ-, μ-, and δ-opioid receptors. The compound was named after Pawhuska, Oklahoma, a place near where the samples of Dalea purpurea that led to its discovery were taken from. Other isolates of the plant with affinity for opioid receptors include Pawhuskin B and Pawhuskin C, though these compounds produce comparatively weak opioid receptor displacement relative to Pawhuskin A. Dalea purpurea was used in traditional Native American medicine to treat various ailments, and pawhuskin A and related isolates may be some of the constituents of the plant which underlay this use.

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References

  1. Neill, D.; Pitman, N. (2004). "Dalea humifosa". IUCN Red List of Threatened Species . 2004: e.T45221A10986647. doi: 10.2305/IUCN.UK.2004.RLTS.T45221A10986647.en . Retrieved 16 November 2021.