David Edwards (engineer)

Last updated
David A. Edwards
David Edwards.jpg
Born
David A. Edwards

(1961-04-06)April 6, 1961
Ann Arbor, Michigan, US
Alma mater Michigan Technological University, BS
Illinois Institute of Technology, PhD
Scientific career
Fields Biomedical engineering
Institutions Harvard University
Website davidideas.com

David A. Edwards (born April 6, 1961) is an American biomedical engineer, and the founder of Sensory Cloud. [1] [2] He was the Gordon McKay Professor of the Practice of Biomedical Engineering at Harvard University. [3] [4]

Contents

Edwards designs inhalable medicines, vaccines and victuals. [5] [6] [7]

In 2001, Edwards was elected a member of the National Academy of Engineering for transfer of scientific principles of engineering to industry, including invention and commercial development of a novel, generic aerosol drug-delivery system.

Education

Edwards studied chemical engineering, receiving a BS from Michigan Technological University in the field in 1983, and a PhD in 1987 from the Illinois Institute of Technology. [8] [9]

Career

Between 1987 and 1995, Edwards held a postdoctoral and lectureship at the Technion in Israel and the Massachusetts Institute of Technology. [10] [11] While at MIT, Robert Langer, a professor at MIT, encouraged Edwards to develop an efficient way for inhalers to deliver medicine to the lungs. [12] Edwards joined the Pennsylvania State University faculty as an Associate Professor of Chemical Engineering in 1995, where he continued to research ways to make medicine inhalable. [13] [14] In 1997, Science published his study on a new type of inhalable aerosol that efficiently delivered drugs to the lungs. [15] [16] Edwards left academia in 1998 when he and Langer founded Advanced Inhalation Research (AIR); the startup was purchased a year later by Alkermes for $114 million. [17] [18] He returned to academia in 2002, joining the Harvard faculty. [19]

Edwards' scientific work in biomedical engineering concerns the research and development of drug delivery platforms for treating infectious diseases in the developing world.[ citation needed ] He was a founder of Advanced Inhalation Research, now part of Alkermes, Inc.,[ citation needed ] of Pulmatrix,[ citation needed ] and of Medicine in Need, an international non-governmental organization aimed at developing new drugs and vaccines for diseases of poverty, such as tuberculosis. [20] [21]

In 2020, Edwards founded the company Sensory Cloud. Sensory Cloud released a nasal inhalable product intended to reduce infected air droplets from viruses like SARS-CoV-2, a strain of coronavirus known to cause COVID-19. [22] [23]

In a February 2021 study in the Proceedings of the National Academy of Sciences of the United States of America , Edwards and his colleagues posited that "exhaled aerosol increases with COVID-19 infection, age, and obesity". [24] [25]

Le Laboratoire

In 2007, Edwards opened "Le Lab" as a space for artists, designers, scientists, and the general public to meet for exhibitions, performances, and discussions in Paris, [26] [27] and then he moved it to 650 East Kendall Street in the Kendall Square area of Cambridge, Massachusetts in 2014. [28] [29] [30] Major exhibitions by artists such as Mark Dion [31] [32] and artist/engineer Chuck Hoberman [33] [34] were shown, as well as innovations developed by Edwards, his associates, and his students. Some of his food-related inventions were available for purchase at Cafe ArtScience, an innovative restaurant associated with Le Laboratoire Cambridge. [35] In December 2019, it was announced that Cafe ArtScience was closing after 5 years of operation, and would be replaced by a new restaurant, called "Senses". [36]

However, the COVID-19 pandemic disrupted these plans, and as of 2022, both the restaurant and Le Laboratoire Cambridge appear to be inactive or closed, either temporarily or permanently.

Personal life

Edwards, his wife and three children have lived alternately in Boston and Paris. [37]

Publications

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References

  1. ↑ Osgood, Charles; Braver, Rita (27 September 2015). "Does a degree in chemical engineering guarantee that its holder will enjoy the sweet smell of success?". CBS Sunday Morning. Retrieved 23 September 2020.
  2. ↑ Pelekanos, Adelle C. (Spring 2008). "Creativity after Google" (PDF). New York Academy of Sciences Magazine. Retrieved 25 September 2020.
  3. ↑ Bradt, Steve (13 March 2008). "Inhaled TB vaccine more effective than traditional shot". The Harvard Gazette . Retrieved 23 September 2020.
  4. ↑ Etherington, Darrell (8 July 2020). "Harvard biomedical engineering professor to launch nasal spray that could reduce COVID-19 transmission risk". TechCrunch . Retrieved 23 September 2020.
  5. ↑ Lazar, Kay (10 April 2009). "Need a Puff of Chocolate? Inhaler Delivers Calorie-free Mist into Your Mouth". The Boston Globe . Retrieved 23 September 2020.
  6. ↑ Wilson, Mark (8 July 2020). "Harvard professor develops a $50 nasal spray to thwart the spread of COVID-19". Fast Company. Retrieved 23 September 2020.
  7. ↑ Edwards, David A.; Hanes, Justin; Caponetti, Giovanni; Hrkach, Jeffrey; Ben-Jebria, Abdelaziz; Eskew, Mary Lou; Mintzes, Jeffrey; Deaver, Daniel; Lotan, Noah; Langer, Robert (20 June 1997). "Large Porous Particles for Pulmonary Drug Delivery". Science. 276 (5320): 1868–1872. doi:10.1126/science.276.5320.1868. PMID   9188534.
  8. ↑ Osgood, Charles; Braver, Rita (27 September 2015). "Does a degree in chemical engineering guarantee that its holder will enjoy the sweet smell of success?". CBS Sunday Morning. Retrieved 23 September 2020.
  9. ↑ Schmadeke, Steve (10 April 2009). "A whiff of innovation--and chocolate". Chicago Tribune. Retrieved 24 September 2020.
  10. ↑ "The Alan S. Michaels Distinguished Lectureship in Medical and Biological Engineering – 2006". MIT. Retrieved 25 September 2020.
  11. ↑ Legg, Heidi (29 September 2015). "The Scent of a Cyborg". TheEditorial. Retrieved 25 September 2020.
  12. ↑ Aoki, Naomi (25 May 2003). "MIT Scientist Sees Science As Means to Change the World and He Has". The Boston Globe.
  13. ↑ Aoki, Naomi (25 May 2003). "MIT Scientist Sees Science As Means to Change the World and He Has". The Boston Globe.
  14. ↑ "The Alan S. Michaels Distinguished Lectureship in Medical and Biological Engineering – 2006". MIT. Retrieved 25 September 2020.
  15. ↑ Scripps News Service (20 June 1997). "New aerosol particle helps fight lung disorders". Deseret News . Retrieved 29 September 2020.
  16. ↑ Edwards, David; Hanes, J; Caponetti, G; Hrkach, J; Ben-Jebria, A; Eskew, M.L.; Mintzes, J; Deaver, D; Lotan, N; Langer, R (20 June 1997). "Large porous particles for pulmonary drug delivery". Science. 276 (5320): 1868–1871. doi:10.1126/science.276.5320.1868. PMID   9188534.
  17. ↑ Kirsner, Scott (3 March 2013). "Harvard dreamer looks for ways to link art, science, and commerce: Innovation Economy". The Boston Globe. Retrieved 23 September 2020.
  18. ↑ Aoki, Naomi (25 May 2003). "MIT Scientist Sees Science As Means to Change the World and He Has". The Boston Globe.
  19. ↑ "The Alan S. Michaels Distinguished Lectureship in Medical and Biological Engineering – 2006". MIT. Retrieved 25 September 2020.
  20. ↑ "Chutzpah Science", Forbes , May 25, 2005.
  21. ↑ "Nose Spray May Slow Spread of Germs", Fox News, November 30, 2004.
  22. ↑ Wilson, Mark (8 July 2020). "Harvard professor develops a $50 nasal spray to thwart the spread of COVID-19". Fast Company . Retrieved 23 September 2020.
  23. ↑ "The Best Inventions of 2020: 100 innovations changing how we live". Time . 19 November 2020. Retrieved 25 August 2021.
  24. ↑ Edwards, David (23 February 2021). "Exhaled aerosol increases with COVID-19 infection, age, and obesity". Proceedings of the National Academy of Sciences of the United States of America . 118 (8): e2021830118. Bibcode:2021PNAS..11821830E. doi: 10.1073/pnas.2021830118 . PMC   7923364 . PMID   33563754.
  25. ↑ Hussein, Tareq; Löndahl, Jakob; Thuresson, Sara; Alsved, Malin; Al-Hunaiti, Afnan; Saksela, Kalle; Aqel, Hazem; Junninen, Heikki; Mahura, Alexander; Kulmalla, Markku (12 March 2021). "Indoor Model Simulation for COVID-19 Transport and Exposure". Int. J. Environ. Res. Public Health. 18 (6): 2927. doi: 10.3390/ijerph18062927 . PMC   7999367 . PMID   33809366.
  26. ↑ Dessent, Blaire. "December 2007, Le Laboratoire". Whitehot Magazine of Contemporary Art. Retrieved 2022-12-31.
  27. ↑ Kirsner, Scott (April 1, 2013). "Accelerating art, science in Lab Cambridge". Boston Globe. Retrieved 2023-01-01.
  28. ↑ "Le Laboratoire Cambridge". C.E. Floyd. C.E. Floyd Company, PBC. Retrieved 2022-12-31.
  29. ↑ Zoia, Gabriella (5 November 2014). "Le Laboratoire creates interactive space for groundbreaking innovation in art, science". The Tufts Daily. Retrieved 2023-01-24.
  30. ↑ Lau, Cat (April 24, 2017). "SPACES – Le Laboratoire Cambridge". Polyfield Magazine. Retrieved 2023-01-24.
  31. ↑ Gayla, Marella A (November 5, 2015). "The Trouble with Jellyfish". The Harvard Crimson. Retrieved 2022-12-31.
  32. ↑ "'The Trouble with Jellyfish'". Harvard Gazette. Harvard University. 26 October 2015. Retrieved 2022-12-31.
  33. ↑ Phongsirivech, Pimploy (26 October 2016). "See Transformable Structures at Le Lab Cambridge". Boston Magazine. Retrieved 2023-01-01.
  34. ↑ "10° (Ten Degrees)". Hoberman Associates. Retrieved 2023-01-01.
  35. ↑ Jiang, Nancy (September 19, 2019). "Cambridge Café ArtScience explores the future of food". The Daily Free Press. Retrieved 2023-01-01.
  36. ↑ Blumenthal, Rachel Leah (20 December 2019). "Cafe Artscience Is Closing in Cambridge After Five Years". Eater Boston. Retrieved 2023-01-01.
  37. ↑ Kirsner, Scott (3 March 2013). "Harvard dreamer looks for ways to link art, science, and commerce: Innovation Economy". The Boston Globe. Retrieved 23 September 2020.
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