Diaporthe toxica | |
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Scientific classification | |
Kingdom: | Fungi |
Division: | Ascomycota |
Class: | Sordariomycetes |
Order: | Diaporthales |
Family: | Diaporthaceae |
Genus: | Diaporthe |
Species: | D. toxica |
Binomial name | |
Diaporthe toxica P.M. Williamson et al, Mycological Research 98(12): 1367 (1994) | |
Diaporthe toxica (anamorph Phomopsis sp. formerly P. leptostromiformis var. leptostromiformis) [1] is a lupin endophyte and occasionally a plant pathogen. The fungus produces secondary metabolites that result in toxicosis of animals such as lupinosis of sheep when infected lupins are ingested by animals. The fungus produces mycotoxins called phomopsins, which cause liver damage. Lupinosis has been incorrectly attributed to Diaporthe woodii but has now been shown to be a mycotoxicosis caused by the recently discovered (1994) teleomorphic fungus Diaporthe toxica. [2] The discovery and naming of this fungus concludes over a century of investigation into the cause of lupinosis since the first major outbreak in Germany in 1872. The infection process and life cycle in both resistant and susceptible lupins has been fully elucidated. [3] This is the first record of resistance in a latent infection. Following this research rapid molecular breeding techniques have been developed leading to the production of many resistant lupin varieties. Lupinosis is no longer considered a disease of major importance to livestock producers in Western Australia. [4] Lupins can now become part of the human diet.
Lupin or lupini beans are the yellow legume seeds of the genus Lupinus. They are traditionally eaten as a pickled snack food, primarily in the Mediterranean basin, Latin America and North Africa. The most ancient evidence of lupin is from ancient Egypt, dating back to the 22nd century BCE. The bitter variety of the beans are high in alkaloids and are extremely bitter unless rinsed methodically. Low alkaloid cultivars called sweet lupins have been bred, and are increasingly planted.
Lupinus albus, commonly known as the white lupin or field lupine, is a member of the genus Lupinus in the family Fabaceae. It is a traditional pulse cultivated in the Mediterranean region.
Basidiobolus ranarum is a filamentous fungus with worldwide distribution. The fungus was first isolated by Eidam in 1886. It can saprophytically live in the intestines of mainly cold-blooded vertebrates and on decaying fruits and soil. The fungus prefers glucose as a carbon source and grows rapidly at room temperature. Basidiobolus ranarum is also known as a cause of subcutaneous zygomycosis, usually causing granulomatous infections on a host's limbs. Infections are generally geographically limited to tropical and subtropical regions such as East and West Africa. Subcutaneous zygomycosis caused by B. ranarum is a rare disease and predominantly affects children and males. Common subcutaneous zygomycosis shows characteristic features and is relatively easy to be diagnosed; while, certain rare cases might show non-specific clinical features that might pose a difficulty on its identification. Although disease caused by this fungus is known to resolve spontaneously on its own although there are a number of treatments available.
Phomopsis cane and leaf spot occurs wherever grapes are grown. Phomopsis cane and leaf spot is more severe in grape-growing regions characterized by a humid temperate climate through the growing season. Crop losses up to 30% have been reported to be caused by Phomopsis cane and leaf spot.
Sporothrix schenckii, a fungus that can be found worldwide in the environment, is named for medical student Benjamin Schenck who in 1896 was the first to isolate it from a human specimen. The species is present in soil as well as in and on living and decomposing plant material such as peat moss. It can infect humans as well as animals and is the causative agent of sporotrichosis, commonly known as "rose handler's disease." The most common route of infection is the introduction of spores to the body through a cut or puncture wound in the skin. Infection commonly occurs in otherwise healthy individuals but is rarely life-threatening and can be treated with antifungals. In the environment it is found growing as filamentous hyphae. In host tissue it is found as a yeast. The transition between the hyphal and yeast forms is temperature dependent making S. schenckii a thermally dimorphic fungus.
Mycobacterium boenickei is a member of the Mycobacterium fortuitum third biovariant complex. They are rapidly growing ubiquitous environmental organisms that normally inhabit soil, dust and water. These organisms frequently are human pathogens that cause a wide spectrum of clinically significant disease. It is important for practitioners to be aware of these organisms as possible etiological agents, as they are resistant to most first-line anti-tuberculous agents.
Mycobacterium brisbanense is a member of the Mycobacterium fortuitum third biovariant complex. They are rapidly growing ubiquitous environmental organisms that normally inhabit soil, dust and water. These organisms frequently are human pathogens that cause a wide spectrum of clinically significant disease. It is important for practitioners to be aware of these organisms as possible etiological agents, as they are resistant to most first-line anti-tuberculous agents.
Diaporthe helianthi is a fungal pathogen that causes Phomopsis stem canker of sunflowers. In sunflowers, Phomopsis helianthi is the causative agent behind stem canker. Its primary symptom is the production of large canker lesions on the stems of sunflower plants. These lesions can eventually lead to lodging and plant death. This disease has been shown to be particularly devastating in southern and eastern regions of Europe, although it can also be found in the United States and Australia. While cultural control practices are the primary method of controlling for Stem Canker, there have been a few resistant cultivars developed in regions of Europe where the disease is most severe.
Ustilaginoidea virens, perfect sexual stage Villosiclava virens, is a plant pathogen which causes the disease "false smut" of rice which reduces both grain yield and grain quality. The disease occurs in more than 40 countries, especially in the rice producing countries of Asia. but also in the U.S. As the common name suggests, it is not a true smut (fungus), but an ascomycete. False smut does not replace all or part of the kernel with a mass of black spores, rather sori form erupting through the palea and lemma forming a ball of mycelia, the outermost layers are spore-producing. Infected rice kernels are always destroyed by the disease.
Diaporthales is an order of sac fungi.
Diaporthe is a genus of endophytic filamentous fungal plant pathogens.
Edwardsiella tarda is a member of the family Hafniaceae. The bacterium is a facultatively anaerobic, small, motile, gram negative, straight rod with flagella. Infection causes Edwardsiella septicemia in channel catfish, eels, and flounder. Edwardsiella tarda is also found in largemouth bass and freshwater species such as rainbow trout. It is a zoonosis and can infect a variety of animals including fish, amphibians, reptiles, and mammals. Edwardsiella tarda has also been the cause of periodic infections for various animals within zoos. E. tarda has a worldwide distribution and can be found in pond water, mud, and the intestine of fish and other marine animals. It is spread by carrier animal feces.
Phomopsis azadirachtae is a fungus, a species of the genus Phomopsis. It has been identified as the fungus responsible for dieback in Azadirachta indica (neem) in India. The species was first identified and described by Sateesh et al in 1997.
Staphylococcus schleiferi is a Gram-positive, cocci-shaped bacterium of the family Staphylococcaceae. It is facultatively anaerobic, coagulase-variable, and can be readily cultured on blood agar where the bacterium tends to form opaque, non-pigmented colonies and beta (β) hemolysis. There exists two subspecies under the species S. schleiferi: Staphylococcus schleiferi subsp. schleiferi and Staphylococcus schleiferi subsp. coagulans.
Staphylococcus pseudintermedius is a gram positive coccus bacteria of the genus Staphylococcus found worldwide. It is primarily a pathogen for domestic animals, but has been known to affect humans as well.S. pseudintermedius is an opportunistic pathogen that secretes immune modulating virulence factors, has many adhesion factors, and the potential to create biofilms, all of which help to determine the pathogenicity of the bacterium. Diagnoses of Staphylococcus pseudintermedius have traditionally been made using cytology, plating, and biochemical tests. More recently, molecular technologies like MALDI-TOF, DNA hybridization and PCR have become preferred over biochemical tests for their more rapid and accurate identifications. This includes the identification and diagnosis of antibiotic resistant strains.
Nannizziopsis vreisii is a keratinophilic microfungus in the Family Onygenaceae of the order Onygenales. Also included in this family are dematophytes and saprophytic species. While the ecology of N. vriessi is not well known, there has been several studies which identifies the Chrysosporium anamorph of N. vriesii as a causal agent of skin lesions in reptiles across several regions. This species is usually identified under a microscope by its white ascomata, and hyaline and globose ascopores. Like many other fungi, N. vreisii has a sexual and asexual state, the asexual states are classified as the genus Chryososporium, Malbranchea or Sporendonema.
Coniochaeta hoffmannii, also known as Lecythophora hoffmannii, is an ascomycete fungus that grows commonly in soil. It has also been categorized as a soft-rot fungus capable of bringing the surface layer of timber into a state of decay, even when safeguarded with preservatives. Additionally, it has pathogenic properties, although it causes serious infection only in rare cases. A plant pathogen lacking a known sexual state, C. hoffmannii has been classified as a "dematiaceous fungus" despite its contradictory lack of pigmentation; both in vivo and in vitro, there is no correlation between its appearance and its classification.
Phaeohyphomycosis is a diverse group of fungal infections, caused by dematiaceous fungi whose morphologic characteristics in tissue include hyphae, yeast-like cells, or a combination of these. It can be associated an array of melanistic filamentous fungi including Alternaria species,Exophiala jeanselmei, and Rhinocladiella mackenziei.
Rhinocladiella mackenziei is a deeply pigmented fungus that is a common cause of human cerebral phaeohyphomycosis. Rhinocladiella mackenziei was believed to be endemic solely to the Middle East, due to the first cases of infection being limited to the region. However, cases of R. mackenziei infection are increasingly reported from regions outside the Middle East. This pathogen is unique in that the majority of cases have been reported from immunologically normal people.
Pithomyces chartarum is a fungus predominantly found in subtropical countries and other localities with warmer climates. However, it occurs throughout the world including the United Kingdom, Europe and Netherlands. Pithomyces chartarum produces a mycotoxin called sporidesmin when it grows on plants, particularly grasses. Presence of the toxin in forage grasses causes facial eczema in sheep, and is especially problematic in areas such as New Zealand where sheep are intensively raised. Other health effect of P. chartarum are not well understood.