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The following page is a list of scientific research that is currently underway or has been previously studied on the International Space Station by the European Space Agency.
ESA's scientific programme for Life and Physical Sciences is defined by and originates from ELIPS: European Programme for Life and Physical Sciences
A description of the experiment and the performance status is given in ESA's Erasmus Experiment Archive (EEA) and in addition a condensed account of the experiment's aim and foundation has been provided in ESA's Human Spaceflight Science Newsletter no.1, 2010. The experiment needs 8-10 human test subjects for medical statistics reasons, for it to be completed. The experiment tests two hypotheses that are based on a more than two decades long research in understanding the reaction of the cardiovascular system to exposure to microgravity. The responses that can be observed in Space in the areas of adjustment of blood pressure, resistance in the circulation, tissue fluid filling and urine excretion, etc. do not fit completely with theories. Thus, the new theories for how the observable reactions could be explained.
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The term micro-g environment is more or less synonymous with the terms weightlessness and zero-g, but emphasising that g-forces are never exactly zero—just very small. The symbol for microgravity, μg, was used on the insignias of Space Shuttle flights STS-87 and STS-107, because these flights were devoted to microgravity research in low Earth orbit.
STS-78 was the fifth dedicated Life and Microgravity Spacelab mission for the Space Shuttle program, flown partly in preparation for the International Space Station project. The mission used the Space Shuttle Columbia, which lifted off successfully from Kennedy Space Center's Launch Pad 39B on June 20, 1996. This marked the 78th flight of the Space Shuttle and 20th mission for Columbia.
Artificial gravity is the creation of an inertial force that mimics the effects of a gravitational force, usually by rotation. Artificial gravity, or rotational gravity, is thus the appearance of a centrifugal force in a rotating frame of reference, as opposed to the force experienced in linear acceleration, which by the equivalence principle is indistinguishable from gravity. In a more general sense, "artificial gravity" may also refer to the effect of linear acceleration, e.g. by means of a rocket engine.
The European Physiology Module (EPM) is an International Standard Payload Rack for the Columbus Laboratory on board the International Space Station. The EPM rack was built by OHB-System in Bremen.
Venturing into the environment of space can have negative effects on the human body. Significant adverse effects of long-term weightlessness include muscle atrophy and deterioration of the skeleton. Other significant effects include a slowing of cardiovascular system functions, decreased production of red blood cells, balance disorders, eyesight disorders and changes in the immune system. Additional symptoms include fluid redistribution, loss of body mass, nasal congestion, sleep disturbance, and excess flatulence. Overall, NASA refers to the various deleterious effects of spaceflight on the human body by the acronym RIDGE.
Biolab is a single-rack multi-user science payload designed for use in the Columbus laboratory of the International Space Station. Biolab support biological research on small plants, small invertebrates, microorganisms, animal cells, and tissue cultures. It includes an incubator equipped with centrifuges in which the preceding experimental subjects can be subjected to controlled levels of accelerations.
Weightlessness is the complete or near-complete absence of the sensation of weight. It is also termed zero gravity, zero G-force, or zero-G.
The eye-tracking device (ETD) is a headmounted device, designed for measurement of 3D eye and head movements under experimental and natural conditions. The tracker permits comprehensive measurement of eye movement and optionally head movement. It represents a tool for the investigation of sensorimotor behaviour, particularly of the vestibular and oculomotor systems in both health and disease.
The Treadmill with Vibration Isolation Stabilization System, commonly abbreviated as TVIS, is a treadmill for use on board the International Space Station and is designed to allow astronauts to run without vibrating delicate microgravity science experiments in adjacent labs. International Space Station treadmills, not necessarily described here, have included the original treadmill, the original TVIS, the БД-2, the Combined Operational Load-Bearing External Resistance Treadmill (COLBERT), and the Treadmill 2. Some share a name, some a design, some a function, some use different (passive) vibration-suppression systems, some it is unclear how they differ.
The International Space Station is a platform for scientific research that requires one or more of the unusual conditions present in low Earth orbit. The primary fields of research include human research, space medicine, life sciences, physical sciences, astronomy and meteorology. The 2005 NASA Authorization Act designated the American segment of the International Space Station as a national laboratory with the goal of increasing the use of the ISS by other federal agencies and the private sector.
m ELIPS - European Programme for Life and Physical Sciences in Space and applications utilising the International Space Station started in 2001 and was intended to cover the activities for the following 5 years. This Microgravity Programme at the European Space Agency (ESA) is an optional programme, with currently 17 ESA member states participating. The ELIPS programme prepares and performs research on the International Space Station, and other uncrewed mission platforms like Sounding Rockets, in fundamental and applied life and physical sciences. ELIPS is the continuation of the earlier European microgravity programmes EMIR 1&2, and the Microgravity Facilities for Columbus, MFC.
Space neuroscience is the scientific study of the central nervous system (CNS) functions during spaceflight. Living systems can integrate the inputs from the senses to navigate in their environment and to coordinate posture, locomotion, and eye movements. Gravity has a fundamental role in controlling these functions. In weightlessness during spaceflight, integrating the sensory inputs and coordinating motor responses is harder to do because gravity is no longer sensed during free-fall. For example, the otolith organs of the vestibular system no longer signal head tilt relative to gravity when standing. However, they can still sense head translation during body motion. Ambiguities and changes in how the gravitational input is processed can lead to potential errors in perception, which affects spatial orientation and mental representation. Dysfunctions of the vestibular system are common during and immediately after spaceflight, such as space motion sickness in orbit and balance disorders after return to Earth.
Vladimir Pletser is Visiting Professor – Scientific Adviser at the Technology and Engineering Centre for Space Utilization (CSU) of the Chinese Academy of Sciences in Beijing, China, since April 2016. He supports the preparation of scientific experiments in microgravity for the future Chinese Space Station and for aircraft parabolic flights. He worked previously from 1985 till early 2016 as senior Physicist-Engineer at the European Space Research and Technology Centre (ESTEC) of ESA.
Astronaut training describes the complex process of preparing astronauts in regions around the world for their space missions before, during and after the flight, which includes medical tests, physical training, extra-vehicular activity (EVA) training, procedure training, rehabilitation process, as well as training on experiments they will accomplish during their stay in space.
Even before the very beginning of human space exploration, serious and reasonable concerns were expressed about exposure of humans to the microgravity of space due to the potential systemic effects on terrestrially-evolved life forms adapted to Earth gravity. Unloading of skeletal muscle, both on Earth via bed-rest experiments and during spaceflight, result in remodeling of muscle. As a result, decrements occur in skeletal muscle strength, fatigue resistance, motor performance, and connective tissue integrity. In addition, there are cardiopulmonary and vascular changes, including a significant decrease in red blood cell mass, that affect skeletal muscle function. This normal adaptive response to the microgravity environment may become a liability resulting in increased risk of an inability or decreased efficiency in crewmember performance of physically demanding tasks during extravehicular activity (EVA) or upon return to Earth.
The growth of plants in outer space has elicited much scientific interest. In the late 20th and early 21st century, plants were often taken into space in low Earth orbit to be grown in a weightless but pressurized controlled environment, sometimes called space gardens. In the context of human spaceflight, they can be consumed as food and/or provide a refreshing atmosphere. Plants can metabolize carbon dioxide in the air to produce valuable oxygen, and can help control cabin humidity. Growing plants in space may provide a psychological benefit to human spaceflight crews. Usually the plants were part of studies or technical development to further develop space gardens or conduct science experiments. To date plants taken into space have had mostly scientific interest, with only limited contributions to the functionality of the spacecraft, however the Apollo Moon tree project was more or less forestry inspired mission and the trees part of a country's bicentennial celebration.
Expedition 52 was the 52nd expedition to the International Space Station. It officially began on June 2, 2017 10:47 UTC, with the undocking of Soyuz MS-03. Transfer of Command from Expedition 51 was done on June 1, 2017.
Locomotion in space includes all actions or methods used to move one's body in microgravity conditions through the outer space environment. Locomotion in these conditions is different from locomotion in a gravitational field. There are many factors that contribute to these differences, and they are crucial when researching long-term survival of humans in space.
SpaceX CRS-24, also known as SpX-24, was a Commercial Resupply Service mission to the International Space Station launched on 21 December 2021, at 10:07:08 UTC. The mission is contracted by NASA and is flown by SpaceX using a Cargo Dragon. This is the fourth flight for SpaceX under NASA's CRS Phase 2 contract awarded in January 2016.
SpaceX CRS-25, also known as SpX-25, was a Commercial Resupply Service mission (CRS) to the International Space Station (ISS) that was launched on 15 July 2022. The mission was contracted by NASA and was flown by SpaceX using their reusable spacecraft, the Cargo Dragon. The vehicle delivered supplies to the crew aboard the ISS along with multiple pieces of equipment that will be used to conduct multiple research investigations aboard the ISS.