Edifenphos

Edifenphos
Names
	Preferred IUPAC name O-Ethyl S,S-diphenyl phosphorodithioate
	Other names O-Ethyl-S,S-diphenyldithiophosphate; EDDP
Identifiers
CAS Number	17109-49-8 ;
3D model (JSmol)	Interactive image ;
ChEBI	CHEBI:34735 ;
ChEMBL	ChEMBL1671900 ;
ChemSpider	26320 ;
ECHA InfoCard	100.037.420
KEGG	C14436 ;
PubChem CID	28292 ;
UNII	770M9U0F8Q ;
CompTox Dashboard (EPA)	DTXSID7041910 ;
	InChI InChI=1S/C14H15O2PS2/c1-2-16-17(15,18-13-9-5-3-6-10-13)19-14-11-7-4-8-12-14/h3-12H,2H2,1H3 Key: AWZOLILCOUMRDG-UHFFFAOYSA-N;
	SMILES CCOP(=O)(Sc1ccccc1)Sc2ccccc2;
Properties
Chemical formula	C14H15O2PS2
Molar mass	310.37 g·mol−1
Density	1.23 g/cm3
Melting point	−25 °C (−13 °F; 248 K)
Solubility in water	56 mg/L (20 °C)
Hazards
	GHS labelling:
Pictograms
Signal word	Danger
Hazard statements	H301, H311, H317, H331, H410
Precautionary statements	P261, P273, P280, P301+P310, P311, P501
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Last updated August 26, 2025

Edifenphos (O-ethyl-S,S-diphenyldithiophosphate, EDDP) is a systemic fungicide that inhibits phosphatidylcholine biosynthesis.^[2]^[3] It was introduced in 1966 by Bayer to combat blast fungus and Pellicularia sasakii in rice cultivation.^[3] It was never authorized for use in the EU.^[4]

References

1 2 3 4 5 6 Recordof Edifenphos in the GESTIS Substance Database of the Institute for Occupational Safety and Health, accessed on 2016-02-01.
↑ Kodama, Osamu; Yamashita, Kenji; Akatsuka, Tadami (1980). "Edifenphos, Inhibitor of Phosphatidylcholine Biosynthesis in Pyricularia oryzae". Agricultural and Biological Chemistry. 44 (5): 1015–1021. doi: 10.1080/00021369.1980.10864095 .
1 2 Matolcsy, György; Nádasy, Miklós; Andriska, Viktor; Terényi, Sándor (1989). Pesticide Chemistry . Elsevier. p. 306. ISBN 978-0444989031.
↑ "Edifenphos: Not Approved". EU Pesticides Database Active Substances. Retrieved 2016-02-01.

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[GESTIS-1] 1 2 3 4 5 6 Recordof Edifenphos in the GESTIS Substance Database of the Institute for Occupational Safety and Health, accessed on 2016-02-01.

[Kodama-2] Kodama, Osamu; Yamashita, Kenji; Akatsuka, Tadami (1980). "Edifenphos, Inhibitor of Phosphatidylcholine Biosynthesis in Pyricularia oryzae". Agricultural and Biological Chemistry. 44 (5): 1015–1021. doi: 10.1080/00021369.1980.10864095 .

[Matolcsy-3] 1 2 Matolcsy, György; Nádasy, Miklós; Andriska, Viktor; Terényi, Sándor (1989). Pesticide Chemistry . Elsevier. p. 306. ISBN 978-0444989031.

[EUDatabase-4] "Edifenphos: Not Approved". EU Pesticides Database Active Substances. Retrieved 2016-02-01.

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Names

Preferred IUPAC name O-Ethyl S,S-diphenyl phosphorodithioate
Other names O-Ethyl-S,S-diphenyldithiophosphate; EDDP
Identifiers
CAS Number	17109-49-8
3D model (JSmol)	Interactive image
ChEBI	CHEBI:34735
ChEMBL	ChEMBL1671900
ChemSpider	26320
ECHA InfoCard	100.037.420
KEGG	C14436
PubChem CID	28292
UNII	770M9U0F8Q
CompTox Dashboard (EPA)	DTXSID7041910
InChI InChI=1S/C14H15O2PS2/c1-2-16-17(15,18-13-9-5-3-6-10-13)19-14-11-7-4-8-12-14/h3-12H,2H2,1H3 Key: AWZOLILCOUMRDG-UHFFFAOYSA-N
SMILES CCOP(=O)(Sc1ccccc1)Sc2ccccc2
Properties
Chemical formula	C₁₄H₁₅O₂PS₂
Molar mass	310.37 g·mol⁻¹
Density	1.23 g/cm³^[1]
Melting point	−25 °C (−13 °F; 248 K)^[1]
Solubility in water	56 mg/L (20 °C)^[1]
Hazards
GHS labelling:
Pictograms	^[1]
Signal word	Danger
Hazard statements	H301, H311, H317, H331, H410^[1]
Precautionary statements	P261, P273, P280, P301+P310, P311, P501^[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references