| Ewingella americana | |
|---|---|
| Scientific classification | |
| Domain: | Bacteria |
| Kingdom: | Pseudomonadati |
| Phylum: | Pseudomonadota |
| Class: | Gammaproteobacteria |
| Order: | Enterobacterales |
| Family: | Yersiniaceae |
| Genus: | Ewingella |
| Species: | E. americana |
| Binomial name | |
| Ewingella americana Grimont et al. 1984 [1] | |
Ewingella americana is a Gram-negative rod, and the only species in the genus Ewingella. It was first identified and characterized in 1983. Ewingella is in the family Yersiniaceae. The organism is rarely reported as a human pathogen, though it has been isolated from a variety of clinical specimens, including wounds, sputum, urine, stool, blood, synovial fluid, [2] conjunctiva, and peritoneal dialysate. [3] The bacterium is named in honor of William H. Ewing, an American biologist who contributed to modern taxonomy.
Respiratory-tract infections following retainment in intensive-care units has been observed in several instances. A case of E. americana causing osteomyelitis and septic arthritis of the shoulder joint in a previous intravenous drug abuser has also been reported. [4] Vascular bypass surgery is a reported risk factor for colonization. [5] [6] Debate currently exists as to this organism's predilection for immunocompromised patients. [7]
E. americana is an organism with simple nutritional needs that can survive in water and citrate solution, and preferentially grows at 4°C. Domestic sources of water, including air conditioning units, ice baths, and wound irrigation systems, have been cited as sources of infection. [8]
In 2025, a study from the Japan Advanced Institute of Science and Technology showed that a single dose of Ewingella americana completely eliminated colorectal cancer tumors in mice. [9] [10]
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