Flavokavain C

Last updated
Flavokavain C
Flavokavain C.svg
Names
Preferred IUPAC name
2′-Hydroxy-4,4′,6′-trimethoxychalcone
Other names
Flavokawain C
Identifiers
3D model (JSmol)
2059845
ChEBI
ChEMBL
ChemSpider
PubChem CID
UNII
  • InChI=1S/C17H16O5/c1-21-13-9-15(20)17(16(10-13)22-2)14(19)8-5-11-3-6-12(18)7-4-11/h3-10,18,20H,1-2H3/b8-5+
    Key: UXUFMIJZNYXWDX-VMPITWQZSA-N
  • O=C(C2=C(O)C=C(OC)C=C2OC)/C=C/C1=CC=C(O)C=C1
Properties
C17H16O5
Molar mass 300.310 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Flavokavain C is a flavokavain found in the kava plant. [1]

See also

Related Research Articles

<span class="mw-page-title-main">Kava</span> Species of plant

Kava or kava kava is a plant in the pepper family, native to the Pacific Islands. The name kava is from Tongan and Marquesan, meaning 'bitter.’ Other names for kava include ʻawa (Hawaiʻi), ʻava (Samoa), yaqona or yagona (Fiji), sakau (Pohnpei), seka (Kosrae), and malok or malogu. Kava can refer to either the plant or a beverage made from its root. The beverage has sedative, anesthetic, psychoactive and euphoriant properties. It is consumed throughout the Pacific Ocean cultures of Polynesia, including Hawaii and Vanuatu, Melanesia, some parts of Micronesia, such as Pohnpei and Kosrae, and the Philippines.

<span class="mw-page-title-main">Kavalactone</span> Group of chemical compounds

Kavalactones are a class of lactone compounds found in kava roots and Alpinia zerumbet. and in several Gymnopilus, Phellinus and Inonotus fungi. Some kavalactones are bioactive.

<span class="mw-page-title-main">Piperaceae</span> Family of flowering plants in the order Piperales

The Piperaceae, also known as the pepper family, are a large family of flowering plants. The group contains roughly 3,600 currently accepted species in five genera. The vast majority of species can be found within the two main genera: Piper and Peperomia.

<span class="mw-page-title-main">Desmethoxyyangonin</span> Chemical compound

Desmethoxyyangonin or 5,6-dehydrokavain is one of the six main kavalactones found in the Piper methysticum (kava) plant.

<span class="mw-page-title-main">Kavain</span> Chemical compound

Kavain is the main kavalactone found mostly in the roots of the kava plant.

The molecular formula C14H12O3 (molar mass: 228.25 g/mol, exact mass: 228.078644 u) may refer to:

Kava may refer to:

<span class="mw-page-title-main">Pipermethystine</span> Chemical compound

Pipermethystine is a toxic alkaloid present in the aerial (aboveground) portions of the kava plant. It is not a kavalactone, containing no lactone structure. Correctly prepared kava root products will contain almost no pipermethystine.

<span class="mw-page-title-main">Flavokavain</span>

Flavokavains are a class of chalconoids found in the kava plant. Currently identified types include flavokavain A, flavokavain B, and flavokavain C.

<span class="mw-page-title-main">Dihydrokavain</span> Chemical compound

Dihydrokavain is one of the six major kavalactones found in the kava plant. It appears to contribute significantly to the anxiolytic effects of kava, based on a study in chicks.

<span class="mw-page-title-main">Yangonin</span> Chemical compound

Yangonin is one of the six major kavalactones found in the kava plant. It has been shown to possess binding affinity for the cannabinoid receptor CB1 (Ki = 0.72 μM), and selectivity vs. the CB2 receptor (Ki >10 μM) where it behaves as an agonist. The CB1 receptor affinity of yangonin suggests that the endocannabinoid system might contribute to the complex human psychopharmacology of the traditional kava drink and the anxiolytic preparations obtained from the kava plant.

<span class="mw-page-title-main">Dihydromethysticin</span> Chemical compound

Dihydromethysticin is one of the six major kavalactones found in the kava plant.

<span class="mw-page-title-main">Methysticin</span> Chemical compound

Methysticin is one of the six major kavalactones found in the kava plant. Research suggests that methysticin and the related compound dihydromethysticin have CYP1A1 inducing effects which may be responsible for their toxicity. Additionally, methysticin has been shown to potentiate GABAA receptor activity, contributing to the overall anxiolytic profile of the kava plant.

<span class="mw-page-title-main">Flavokavain A</span> Chemical compound

Flavokavain A is a flavokavain found in the kava plant. It induces apoptosis in bladder cancer cells via a Bax protein-dependent and mitochondria-dependent apoptotic pathway.

<span class="mw-page-title-main">Flavokavain B</span> Chemical compound

Flavokavain B is a flavokavain found in the kava plant. In 2010 a paper was published identifying it as a glutathione-depleting hepatotoxin.

The molecular formula C15H16O5 (molar mass: 276.28 g/mol, exact mass: 276.099774 u) may refer to:

The molecular formula C17H16O5 (molar mass: 300.30 g/mol, exact mass: 300.099773 u) may refer to:

The molecular formula C17H16O4 (exact mass : 284.104859, molar mass : 284.31 g/mol) may refer to :

The molecular formula C18H18O5 (molar mass: 314.33 g/mol, exact mass: 314.115424 u) may refer to:

The molecular formula C15H14O5 (molar mass : 274.26 g/mol, exact mass : 274.084123) may refer to:

References

  1. ↑ Dharmaratne, H. Ranjith W.; N. P. Dhammika Nanayakkara; Ikhlas A. Khan (February 2002). "Kavalactones from Piper methysticum, and their 13C NMR spectroscopic analyses". Phytochemistry. 59 (4): 429–33. doi:10.1016/S0031-9422(01)00443-5. PMID   11830162.


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