 | |
| Names | |
|---|---|
| Preferred IUPAC name 2′-Hydroxy-4,4′,6′-trimethoxychalcone | |
| Other names Flavokawain C | |
| Identifiers | |
3D model (JSmol) | |
| 2059845 | |
| ChEBI | |
PubChem CID | |
CompTox Dashboard (EPA) | |
| |
| Properties | |
| C17H16O5 | |
| Molar mass | 300.310 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
 verify (what is   ?) | |
| Infobox references | |
Flavokavain C is a flavokavain found in the kava plant. [1]
Kava or kava kava is a crop of the Pacific Islands. The name kava is from Tongan and Marquesan, meaning 'bitter'; other names for kava include ʻawa (Hawaiʻi), ʻava (Samoa), yaqona or yagona (Fiji), sakau (Pohnpei), seka (Kosrae), and malok or malogu. Kava is consumed for its sedating effects throughout the Pacific Ocean cultures of Polynesia, including Hawaii, Vanuatu, Melanesia, and some parts of Micronesia, such as Palau. To a lesser extent, it is consumed in nations where it is exported as a herbal medicine.
Kavalactones are a class of lactone compounds found in the kava shrub. Kavalactones are under research for potential to have various psychotropic effects, including anxiolytic and sedative/hypnotic activities.
A hepatotoxin is a toxic chemical substance that damages the liver.
2-Pyrone (α-pyrone or pyran-2-one) is an unsaturated cyclic chemical compound with the molecular formula C5H4O2. It is isomeric with 4-pyrone.
Desmethoxyyangonin or 5,6-dehydrokavain is one of the six main kavalactones found in the Piper methysticum (kava) plant.
Kavain is the main kavalactone found mostly in the roots of the kava plant.
The molecular formula C14H12O3 (molar mass: 228.25 g/mol, exact mass: 228.078644 u) may refer to:
Pipermethystine is a toxic alkaloid present in the aerial (aboveground) portions of the kava plant. It is not a kavalactone, containing no lactone structure. Correctly prepared kava root products will contain almost no pipermethystine.
Flavokavains are a class of chalconoids found in the kava plant. Currently identified types include flavokavain A, flavokavain B, and flavokavain C.
Dihydrokavain is one of the six major kavalactones found in the kava plant. It appears to contribute significantly to the anxiolytic effects of kava, based on a study in chicks.
Yangonin is one of the six major kavalactones found in the kava plant. It has been shown to possess binding affinity for the cannabinoid receptor CB1 (Ki = 0.72 μM), and selectivity vs. the CB₂ receptor (K(i)>10 μM) where it behaves as an agonist. The CB₁ receptor affinity of yangonin suggests that the endocannabinoid system might contribute to the complex human psychopharmacology of the traditional kava drink and the anxiolytic preparations obtained from the kava plant.
Dihydromethysticin is one of the six major kavalactones found in the kava plant.
Methysticin is one of the six major kavalactones found in the kava plant. Research suggests that methysticin and the related compound dihydromethysticin have CYP1A1 inducing effects which may be responsible for their toxicity.
Flavokavain A is a flavokavain found in the kava plant. It induces apoptosis in bladder cancer cells via a Bax protein-dependent and mitochondria-dependent apoptotic pathway.
Flavokavain B is a flavokavain found in the kava plant. In 2010 a paper was published identifying it as a glutathione-depleting hepatotoxin.
The molecular formula C17H16O5 (molar mass: 300.30 g/mol, exact mass: 300.099773 u) may refer to:
The molecular formula C18H18O5 (molar mass: 314.33 g/mol, exact mass: 314.115424 u) may refer to:
The molecular formula C15H14O5 (molar mass : 274.26 g/mol, exact mass : 274.084123) may refer to:
The molecular formula C15H14O4 may refer to:
Lava Cola is a cola drink produced in Vanuatu by Vanuatu Beverage Ltd. It contains a kavalactone additive, kava consumption being traditionally important in western Pacific nations. Lava Cola has been described as an "anti-energy drink". Australian media have noted that it "produces the calming effect of kava without the muddy taste," adding that, while kava itself is an acquired taste, Lava Cola may well be suitable for export.
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