Haemophilus parainfluenzae | |
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Scientific classification ![]() | |
Domain: | Bacteria |
Kingdom: | Pseudomonadati |
Phylum: | Pseudomonadota |
Class: | Gammaproteobacteria |
Order: | Pasteurellales |
Family: | Pasteurellaceae |
Genus: | Haemophilus |
Species: | H. parainfluenzae |
Binomial name | |
Haemophilus parainfluenzae Rivers 1922 (Approved Lists 1980) [1] | |
Haemophilus parainfluenzae is a species of Haemophilus .
It is one of the HACEK organisms. [2] H. parainfluenzae is an opportunistic pathogen that has been associated with endocarditis, bronchitis, otitis, conjunctivitis, pneumonia, abscesses and genital tract infections.
H. parainfluenzae biotypes I and II are capable of natural genetic transformation. [3] Natural genetic transformation is a bacterial adaptation for DNA transfer. In order for a bacterium to bind, take up and recombine exogenous DNA into its genome it must enter a special physiological state termed natural competence. In H. parainfluenzae, competence is induced during the late stationary phase of growth. [3] Natural DNA transformation may play a major role in the exchange of genetic information among H. parainfluenzae isolates.
Acute H. parainfluenzae infections must be treated with antibiotics. Beta-lactam agents such as amoxicillin and ampicillin are antibiotics that are effective against H. parainfluenzae. The Duration of Antibiotic Therapy depends on the severity of the infection. In 40% of infective endocarditis cases caused by H. parainfluenzae, the best treatment is a valve replacement. [4]