Angioplasty, also known as balloon angioplasty and percutaneous transluminal angioplasty (PTA), is a minimally invasive endovascular procedure used to widen narrowed or obstructed arteries or veins, typically to treat arterial atherosclerosis.
A coronary catheterization is a minimally invasive procedure to access the coronary circulation and blood filled chambers of the heart using a catheter. It is performed for both diagnostic and interventional (treatment) purposes.
Restenosis is the recurrence of stenosis, a narrowing of a blood vessel, leading to restricted blood flow. Restenosis usually pertains to an artery or other large blood vessel that has become narrowed, received treatment to clear the blockage, and subsequently become re-narrowed. This is usually restenosis of an artery, or other blood vessel, or possibly a vessel within an organ.
Interventional cardiology is a branch of cardiology that deals specifically with the catheter based treatment of structural heart diseases. Andreas Gruentzig is considered the father of interventional cardiology after the development of angioplasty by interventional radiologist Charles Dotter.
Andreas Roland Grüntzig was a German radiologist and cardiologist, with foundational interest, training and research in epidemiology and angiology. He is known for being the first to develop successful balloon angioplasty for expanding lumens of narrowed arteries. He was born in Dresden.
Percutaneous coronary intervention (PCI) is a minimally invasive non-surgical procedure used to treat narrowing of the coronary arteries of the heart found in coronary artery disease. The procedure is used to place and deploy coronary stents, a permanent wire-meshed tube, to open narrowed coronary arteries. PCI is considered 'non-surgical' as it uses a small hole in a peripheral artery (leg/arm) to gain access to the arterial system, an equivalent surgical procedure would involve the opening of the chest wall to gain access to the heart area. The term 'coronary angioplasty with stent' is synonymous with PCI. The procedure visualises the blood vessels via fluoroscopic imaging and contrast dyes. PCI is performed by an interventional cardiologists in a catheterization laboratory setting.
Firozpur district, also known as Ferozepur district, is one of the twenty-three districts in the state of Punjab, India. Firozpur district comprises an area of 2,190 km2 (850 sq mi).
A drug-eluting stent (DES) is a tube made of a mesh-like material used to treat narrowed arteries in medical procedures both mechanically and pharmacologically. A DES is inserted into a narrowed artery using a delivery catheter usually inserted through a larger artery in the groin or wrist. The stent assembly has the DES mechanism attached towards the front of the stent, and usually is composed of the collapsed stent over a collapsed polymeric balloon mechanism, the balloon mechanism is inflated and used to expand the meshed stent once in position. The stent expands, embedding into the occluded artery wall, keeping the artery open, thereby improving blood flow. The mesh design allows for stent expansion and also for new healthy vessel endothelial cells to grow through and around it, securing it in place.
The history of invasive and interventional cardiology is complex, with multiple groups working independently on similar technologies. Invasive and interventional cardiology is currently closely associated with cardiologists, though the development and most of its early research and procedures were performed by diagnostic and interventional radiologists.
A coronary stent is a tube-shaped device placed in the coronary arteries that supply blood to the heart, to keep the arteries open in patients suffering from coronary heart disease. The vast majority of stents used in modern interventional cardiology are drug-eluting stents (DES). They are used in a medical procedure called percutaneous coronary intervention (PCI). Coronary stents are divided into two broad types: drug-eluting and bare metal stents. As of 2023, drug-eluting stents were used in more than 90% of all PCI procedures. Stents reduce angina and have been shown to improve survival and decrease adverse events after a patient has suffered a heart attack—medically termed an acute myocardial infarction.
Pulmonary artery stenosis (PAS) is a narrowing of the pulmonary artery. The pulmonary artery is a blood vessel moving blood from the right side of the heart to the lungs. This narrowing can be due to many causes, including infection during pregnancy, a congenital heart defect, a problem with blood clotting in childhood or early adulthood, or a genetic change.
Julio Palmaz is a doctor of vascular radiology at University of Texas Health Science Center at San Antonio. He studied at the National University of La Plata in Argentina, earning his medical degree in 1971. He then practiced vascular radiology at the San Martin University Hospital in La Plata before moving to the University of Texas Health and Science Center at San Antonio. He is known for inventing the balloon-expandable stent, for which he received a patent filed in 1985. It was recognized in Intellectual Property International Magazine as one of "Ten Patents that Changed the World" in the last century. His early stent research artifacts are now part of the medical collection of the Smithsonian Institution in Washington, DC. He continues to innovate on his initial designs, developing new endovascular devices.
Dr Purshotam Lal is an Indian Interventional cardiologist who has to his credit the pioneering of over 20 interventional cardiology procedures for the first time in India, some of which were the first time in the World. Trained in UK, US and Germany, and he has held various faculty positions including Professor, Advisor, etc.
Ulrich Sigwart is a German retired cardiologist known for his pioneering role in the conception and clinical use of stents to keep blood vessels open, and introducing a non-surgical intervention, alcohol septal ablation for the treatment of hypertrophic obstructive cardiomyopathy.
Mathew Samuel Kalarickal is an Indian cardiologist widely known as the father of angioplasty in India. He specializes in coronary angioplasty, carotid stenting, coronary stenting and rotablator atherectomy.
Ashok Seth is an Indian interventional cardiologist, credited with the performance of over 50,000 angiograms and 20,000 angioplasties, which has been included in the Limca Book of Records, a book for achievements and records from an Indian perspective. He is a Fellow of the Royal Colleges of Physicians of London, Edinburgh and Ireland and serves as the chief cardiologist, holding the chairs of the department of cardiovascular sciences and cardiology council at the Fortis Healthcare. Seth, a recipient of the Order of Isabella the Catholic, was honored by the Government of India with the fourth highest Indian civilian award of Padma Shri, in 2003, followed by Padma Bhushan, the third highest Indian civilian award, in 2015.
Nagarur Gopinath was an Indian surgeon and one of the pioneers of cardiothoracic surgery in India. He is credited with the first successful performance of open heart surgery in India which he performed in 1962. He served as the honorary surgeon to two Presidents of India and was a recipient of the fourth highest Indian civilian award of Padma Shri in 1974 and Dr. B. C. Roy Award, the highest Indian medical award in 1978 from the Government of India.
Daljeet Singh Gambhir is an Indian cardiologist, medical academic, researcher and inventor and the Group Director of Cardiology at Kailash Group of Hospitals and Heart Institute, Noida. He is the inventor of Infinnium Paclitaxel-Eluting Stent, a reportedly cheaper drug-eluting stent which he first presented at the EuroPCR meeting held in Paris in 2003. A fellow of the National Academy of Medical Sciences and an honorary fellow of the Indian College of Cardiology, he is reported to have performed over 10,000 coronary interventions. The Government of India awarded him the fourth highest civilian honour of the Padma Shri, in 2016, for his contributions to medicine.
Donald S. Baim was a researcher and clinician in the field of interventional cardiology. Baim's primary research focused on coronary blood flow, catheter intervention in heart disease, and congestive heart failure. His work helped to shift the use of catheters from a purely diagnostic tool to a therapeutic tool. After receiving a medical degree from Yale and initial medical training, residency and a fellowship at Stanford University Medical Center, Baim spent the bulk of his career at Beth Israel Hospital and at the Brigham and Women's Hospital in Boston. In 1993, Baim founded the Beth Israel Hospital's Cardiovascular Data Analysis Center (CDAC) -- later to be named Harvard Clinical Research Institute (HCRI). Baim died of cancer in November 2009. In October 2016, HCRI changed its name to the Baim Institute for Clinical Research.
Alfredo E. Rodríguez is an Argentine interventional cardiologist, clinical researcher, and author. He is the Chief of Interventional Cardiology Service at Otamendi Hospital and Director and Founder of the Cardiovascular Research Center (CECI) a non -profit Research Organization in Buenos Aires Argentina.
