Iotatorquevirus

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Iotatorquevirus
Virus classification Red Pencil Icon.png
(unranked): Virus
Realm: incertae sedis
Kingdom: incertae sedis
Phylum: incertae sedis
Class: incertae sedis
Order: incertae sedis
Family: Anelloviridae
Genus:Iotatorquevirus

Iotatorquevirus is a genus of viruses in the family Anelloviridae , in group II in the Baltimore classification. It includes one species: Torque teno sus virus 1a. [1]

Contents

Virology

The virons are small and non-enveloped.

The viruses are usually acquired soon after birth and may invade virtually any tissue in the body. [2]

They are widespread in the pig population. [3] [4]

Genome

Iotatorqueviruses have a circular, single-stranded DNA genome. The genome is negative-sense.

Clinical

Postweaning multisystemic wasting syndrome has been causally associated with porcine circovirus type 2. [5] The Iotatorquevirus have also been linked with this syndrome but a causative role—if one exists—has yet to be established. [6]

Related Research Articles

<i>Parvoviridae</i> Family of viruses

Parvoviruses are a family of animal viruses that constitute the family Parvoviridae. They have linear, single-stranded DNA (ssDNA) genomes that typically contain two genes encoding for a replication initiator protein, called NS1, and the protein the viral capsid is made of. The coding portion of the genome is flanked by telomeres at each end that form into hairpin loops that are important during replication. Parvovirus virions are small compared to most viruses, at 23–28 nanometers in diameter, and contain the genome enclosed in an icosahedral capsid that has a rugged surface.

Circoviridae is a family of DNA viruses. Birds and mammals serve as natural hosts. There are 101 species in this family, assigned to 2 genera. Diseases associated with this family include: PCV-2: postweaning multisystemic wasting syndrome; CAV: chicken infectious anemia.

<i>Coronaviridae</i> Family of viruses in the order Nidovirales

Coronaviridae is a family of enveloped, positive-strand RNA viruses which infect amphibians, birds, and mammals. The group includes the subfamilies Letovirinae and Orthocoronavirinae; the members of the latter are known as coronaviruses.

<i>Orthohepevirus</i> Genus of viruses

Orthohepevirus is a genus of viruses assigned to the family Hepeviridae. Orthohepevirus is a fairly isolated viral genus in which the virions are characterized by round, non-enveloped and isometric capsids with a diameter of 27–34 nm. The hepatitis E virus belongs this genus as the species Orthohepevirus A

Porcine circoviral disease (PCVD) and porcine circovirus associated disease (PCVAD), is a disease seen in domestic pigs. This disease causes illness in piglets, with clinical signs including progressive loss of body condition, visibly enlarged lymph nodes, difficulty in breathing, and sometimes diarrhea, pale skin, and jaundice. PCVD is very damaging to the pig-producing industry and has been reported worldwide. PCVD is caused by Porcine circovirus 2 (PCV-2).

Betaarterivirus suid 1, formerly Porcine reproductive and respiratory syndrome virus (PRRSV), is a virus that causes a disease of pigs, called porcine reproductive and respiratory syndrome (PRRS), also known as blue-ear pig disease. This economically important, panzootic disease causes reproductive failure in breeding stock and respiratory tract illness in young pigs.

<span class="mw-page-title-main">Canine coronavirus</span> Species of virus

Canine coronavirus (CCoV) is an enveloped, positive-sense, single-stranded RNA virus which is a member of the species Alphacoronavirus 1. It causes a highly contagious intestinal disease worldwide in dogs. The infecting virus enters its host cell by binding to the APN receptor. It was discovered in 1971 in Germany during an outbreak in sentry dogs. The virus is a member of the genus Alphacoronavirus and subgenus Tegacovirus.

<span class="mw-page-title-main">Porcine circovirus</span> Species of virus

Porcine circovirus (PCV) is a group of four single-stranded DNA viruses that are non-enveloped with an unsegmented circular genome. They are members of the genus Circovirus that can infect pigs. The viral capsid is icosahedral and approximately 17 nm in diameter.

Porcine parvovirus (PPV), a virus in the species Ungulate protoparvovirus 1 of genus Protoparvovirus in the virus family Parvoviridae, causes reproductive failure of swine characterized by embryonic and fetal infection and death, usually in the absence of outward maternal clinical signs. The disease develops mainly when seronegative dams are exposed oronasally to the virus anytime during about the first half of gestation, and conceptuses are subsequently infected transplacentally before they become immunocompetent. There is no definitive evidence that infection of swine other than during gestation is of any clinical or economic significance. The virus is ubiquitous among swine throughout the world and is enzootic in most herds that have been tested. Diagnostic surveys have indicated that PPV is the major infectious cause of embryonic and fetal death. In addition to its direct causal role in reproductive failure, PPV can potentiate the effects of porcine circovirus type II (PCV2) infection in the clinical course of postweaning multisystemic wasting syndrome (PMWS). Approximately 38 peoples have died of the virus.

<i>Gammaherpesvirinae</i> Subfamily of viruses

Gammaherpesvirinae is a subfamily of viruses in the order Herpesvirales and in the family Herpesviridae. Viruses in Gammaherpesvirinae are distinguished by reproducing at a more variable rate than other subfamilies of Herpesviridae. Mammals serve as natural hosts. There are 43 species in this subfamily, divided among 7 genera with three species unassigned to a genus. Diseases associated with this subfamily include: HHV-4: infectious mononucleosis. HHV-8: Kaposi's sarcoma.

Erbovirus is a genus of viruses in the order Picornavirales, in the family Picornaviridae. Horses serve as natural hosts. There is only one species in this genus: Erbovirus A. Diseases associated with this genus include: upper respiratory tract disease with viremia and fecal shedding. Viruses belonging to the genus Erbovirus have been isolated in horses with acute upper febrile respiratory disease. The structure of the Erbovirus virion is icosahedral, having a diameter of 27–30 nm.

Anelloviridae is a family of viruses. They are classified as vertebrate viruses and have a non-enveloped capsid, which is round with isometric, icosahedral symmetry and has a triangulation number of 3.

<i>Corticovirus</i> Genus of viruses

Corticovirus is a genus of viruses in the family Corticoviridae. Corticoviruses are bacteriophages; that is, their natural hosts are bacteria. The genus contains two species. The name is derived from Latin cortex, corticis. However, prophages closely related to PM2 are abundant in the genomes of aquatic bacteria, suggesting that the ecological importance of corticoviruses might be underestimated. Bacteriophage PM2 was first described in 1968 after isolation from seawater sampled from the coast of Chile.

Alphatorquevirus is a genus of viruses in the family Anelloviridae, in group II in the Baltimore classification. It encompasses many species of the virus formerly known as TTV, transfusion transmitted virus, or torque teno virus, SENV, SANBAN, and others. The genus contains 26 species.

Betatorquevirus is a genus of viruses in the family Anelloviridae, in group II in the Baltimore classification. The genus Betatorquevirus includes all "torque teno mini viruses" (TTMV), numbered from 1 to 38 as 38 species.

Gammatorquevirus is a genus of viruses in the family Anelloviridae, in group II in the Baltimore classification. It contains 15 species. The fifteen species are all named "torque teno midi virus" (TTMDV), number 1–15.

<i>Circovirus</i> Genus of viruses

Circovirus is a genus of viruses, in the family Circoviridae. Birds and pigs serve as natural hosts, though dogs have been shown to be infected as well. It is a single stranded DNA virus (ssDNA). There are 49 species in this genus. Some members of this genus cause disease: PCV-1 is non pathogenic, while PCV-2 causes postweaning multisystemic wasting syndrome (PMWS).

Kappatorquevirus is a genus of viruses, in the family Anelloviridae. Pigs serve as natural hosts. There are two species in this genus. Diseases associated with this genus include: possibly post-weaning multisystemic wasting syndrome (PMWS).

Lambdatorquevirus is a genus of viruses, in the family Anelloviridae. Sea lions serve as natural hosts. There are six species in this genus.

Torque teno virus, belonging to the family Anelloviridae, is a group of virus strains that are non-enveloped, with a single-stranded circular DNA genome ranging from 2.6 to 2.8 kb in size. These swine infecting anelloviruses are divided into two genera: Iotatorquevirus and Kappatorquevirus. Torque teno sus virus has been found in pigs worldwide. TTSuVs are mainly transmitted by fecal-oral route. The prevalence of these viruses is relatively high. For now, there is not known disease caused exclusively by TTSuV. There is the possibility that TTSuV may worsen the progression of other diseases and therefore increase the economic losses for pig industry.

References

  1. "Virus Taxonomy: 2020 Release". International Committee on Taxonomy of Viruses (ICTV). March 2021. Retrieved 23 May 2021.
  2. Aramouni M, Segalés J, Cortey M, Kekarainen T (2010). "Age-related tissue distribution of swine Torque teno sus virus 1 and 2". Vet. Microbiol. 146 (3–4): 350–3. doi:10.1016/j.vetmic.2010.05.036. PMID   20646878.
  3. Brink M, Ståhl K, Masembe C, Okurut AR, Berg M, Blomström AL (2012). "First time molecular detection and phylogenetic relationships of torque teno sus virus 1 and 2 in domestic pigs in Uganda: further evidence for a global distribution". Virol. J. 9: 39. doi:10.1186/1743-422X-9-39. PMC   3298808 . PMID   22336096.
  4. Kekarainen T, Segalés J (2012). "Torque teno sus virus in pigs: an emerging pathogen?". Transbound Emerg Dis. 59 (Suppl 1): 103–8. doi: 10.1111/j.1865-1682.2011.01289.x . PMID   22252126.
  5. Wallgren P, Belák K, Ehlorsson CJ, Bergström G, Lindberg M, Fossum C, Allan GM, Robertsson JA (2007). "Postweaning multisystemic wasting syndrome (PMWS) in Sweden from an exotic to an endemic disease". Vet Q. 29 (4): 122–37. doi:10.1080/01652176.2007.9695238. PMID   18265702.
  6. Nieto D, Aramouni M, Grau-Roma L, Segalés J, Kekarainen T (2011). "Dynamics of Torque teno sus virus 1 (TTSuV1) and 2 (TTSuV2) DNA loads in serum of healthy and postweaning multisystemic wasting syndrome (PMWS) affected pigs" (PDF). Vet. Microbiol. 152 (3–4): 284–90. doi:10.1016/j.vetmic.2011.05.020. PMID   21680113.