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Endocytosis is a cellular process in which substances are brought into the cell. The material to be internalized is surrounded by an area of cell membrane, which then buds off inside the cell to form a vesicle containing the ingested materials. Endocytosis includes pinocytosis and phagocytosis. It is a form of active transport.
Endosomes are a collection of intracellular sorting organelles in eukaryotic cells. They are parts of the endocytic membrane transport pathway originating from the trans Golgi network. Molecules or ligands internalized from the plasma membrane can follow this pathway all the way to lysosomes for degradation or can be recycled back to the cell membrane in the endocytic cycle. Molecules are also transported to endosomes from the trans Golgi network and either continue to lysosomes or recycle back to the Golgi apparatus.
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References
- ↑ Wells, W. A. (2007). "Ira Mellman: From endosomes to industry". The Journal of Cell Biology. 177 (4): 570–571. doi:10.1083/jcb.1774pi. PMC 2064202 . PMID 17517958.
- 1 2 3 Nair, P. (2012). "Profile of Ira Mellman". Proceedings of the National Academy of Sciences . 109 (23): 8790–2. Bibcode:2012PNAS..109.8790N. doi: 10.1073/pnas.1207791109 . PMC 3384157 . PMID 22645337.
- ↑ Miller, D. H. (1 November 1974). "The chemical composition of the cell wall of Chlamydomonas gymnogama and the concept of a plant cell wall protein". The Journal of Cell Biology. 63 (2): 420–429. doi:10.1083/jcb.63.2.420. PMC 2110943 . PMID 4607708.
- ↑ "FirstWord". firstwordpharma.com. Retrieved 2024-08-17.
- ↑ "Genentech dissolves cancer immunology group, and research executive Ira Mellman will leave company". Endpoints News. Retrieved 2024-08-17.
- ↑ "Margaret Moench, Art Student, Married to Ira Seth Mellman, Doctoral Candidate". The New York Times. 20 September 1976.
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