Judy Armitage | |
---|---|
Born | Judith Patricia Armitage 21 February 1951 Shelley, West Riding of Yorkshire, England. |
Alma mater | University College London |
Known for | Study of chemotactic mechanisms to control bacterial motion |
Spouse | John Jefferys |
Children | 2 |
Scientific career | |
Fields | Molecular and cellular biochemistry |
Institutions | University of Oxford University College London Merton College, Oxford |
Thesis | Comparative biochemistry and physiology of the short and long forms of Proteus mirabilis (1976) |
Judith Patricia ArmitageFRS (born 1951) is a British molecular and cellular biochemist at the University of Oxford.
Armitage was born on 21 February 1951 in Shelley, Yorkshire, England. [1] She attended Selby Girls' High School, an all-female grammar school, then located in the West Riding of Yorkshire. In her sixth form, the school became the co-educational Selby Grammar School.
Armitage earned a BSc in microbiology at University College London in 1972, and was awarded a PhD in 1976 for research on the bacterium Proteus mirabilis . [2] She remained at UCL in the laboratory of Micheal Evans for her postdoctoral work. [3]
Armitage's research is largely based on the motion of bacteria by flagellar rotation and the chemotactic mechanisms used to control that motion. [4] Armitage was appointed Lecturer in Biochemistiry at Oxford in 1985 and was awarded the Title of Distinction of Professor of Biochemistry in 1996. Armitage is a fellow of Merton College, Oxford [5] and has served as Director of the Oxford University Centre for Integrative Systems Biology since 2006. [6] [7] [8] [9] [10]
Armitage was elected President of the Microbiology Society for 2019. [11]
Armitage was awarded a Lister Institute Research Fellowship in 1982. [12]
In 2010 Armitage was elected a member of the European Molecular Biology Organisation [13] and in 2011 was elected a Fellow of the American Academy of Microbiology and a Fellow of the Royal Society of Biology. [6]
Armitage was elected a Fellow of the Royal Society (FRS) in 2013. Her nomination reads: [14]
Judith Armitage is distinguished for pioneering contributions to the understanding of spatio-temporal complexity and cellular organisation in bacteria. Combining biophysics and in vivo light microscopy with molecular genetics she discovered a new protein partitioning system that exerts spatial control over sensory signalling pathways. Co-crystal structural studies of a sensory kinase and its cognate response regulator directly revealed single amino acid changes involved in pathway discrimination. The first direct measurements of the dynamics of rotor and stator proteins in rotating flagellar motors revealed exchange with free protein pools, an observation which fundamentally changed our understanding of bacterial motility and behaviour.
In January 2019 she was elected president of the Microbiology Society for a term of three years. [15]
Angela Vincent is a British neuroscientist who is emeritus professor at the University of Oxford and a Fellow of Somerville College, Oxford.
Sir John Ernest Walker is a British chemist who won the Nobel Prize in Chemistry in 1997. As of 2015 Walker is Emeritus Director and Professor at the MRC Mitochondrial Biology Unit in Cambridge, and a Fellow of Sidney Sussex College, Cambridge.
Julius Adler was an American biochemist. He had been an Emeritus Professor of biochemistry and genetics at the University of Wisconsin–Madison since 1997.
The Department of Biochemistry of Oxford University is located in the Science Area in Oxford, England. It is one of the largest biochemistry departments in Europe. The Biochemistry Department is part of the University of Oxford's Medical Sciences Division, the largest of the university's four academic divisions, which has been ranked first in the world for biomedicine.
Patricia Hannah Clarke FRS was a British biochemist.
Reginald John Ellis is a British scientist.
Sir Christopher Martin Dobson was a British chemist, who was the John Humphrey Plummer Professor of Chemical and Structural Biology in the Department of Chemistry at the University of Cambridge, and Master of St John's College, Cambridge.
Professor Keith Gull is a Wellcome Trust Principal Research Fellow and Professor of Molecular microbiology at the Sir William Dunn School of Pathology, University of Oxford. He was the principal of St Edmund Hall, Oxford from 1 October 2009 to 30 September 2018, succeeding Michael Mingos.
Sheena Elizabeth Radford is a British biophysicist, and Astbury Professor of Biophysics and a Royal Society Research Professor in the Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology at the University of Leeds. Radford is the Associate Editor of the Journal of Molecular Biology.
James Henderson Naismith is a Scot, Professor of Structural Biology and since autumn of 2023 the Head of the Mathematical, Physical, and Life Science Division (MPLS) Division at the University of Oxford. He was the inaugural Director of the Rosalind Franklin Institute and Director of the Research Complex at Harwell. He previously served as Bishop Wardlaw Professor of Chemical Biology at the University of St Andrews. He was a member of Council of the Royal Society (2021-2022). He is also currently the Vice-Chair of Council of the European X-ray Free Electron Laser and Vice-President (non-clinical) of The Academy of Medical Sciences.
Jane Clarke is a British biochemist and academic. Since October 2017, she has served as President of Wolfson College, Cambridge. She is also Professor of Molecular Biophysics, a Wellcome Trust Senior Research Fellow in the Department of Chemistry at the University of Cambridge. She was previously a Fellow of Trinity Hall, Cambridge. In 2023, she was elected to the National Academy of Sciences.
Benjamin Guy Davis is a British chemist who is Professor of Chemical biology in the Department of Pharmacology and a member of the Faculty in the Department of Chemistry at the University of Oxford and a Fellow of Pembroke College, Oxford. He holds the role of Science Director for Next Generation Chemistry (2019-2024) and Deputy Director (2020-) at the Rosalind Franklin Institute.
Edith Yvonne Jones is a British molecular biologist who is director of the Cancer Research UK Receptor Structure Research Group at the University of Oxford and a Fellow of Jesus College, Oxford. She is widely known for her research on the molecular biology of cell surface receptors and signalling complexes.
Jan Löwe is a German molecular and structural biologist and the Director of the Medical Research Council (MRC) Laboratory of Molecular Biology (LMB) in Cambridge, UK. He became Director of the MRC-LMB in April 2018, succeeding Sir Hugh Pelham. Löwe is known for his contributions to the current understanding of bacterial cytoskeletons.
Judy Hirst is a British scientist specialising in mitochondrial biology. She is Director of the MRC Mitochondrial Biology Unit at the University of Cambridge.
Tracy Palmer is a British microbiologist who is a professor of microbiology in the Biosciences Institute at Newcastle University in Tyne & Wear, England. She is known for her work on the twin-arginine translocation (Tat) pathway.
Renee Elizabeth Sockett is a professor and microbiologist in the School of Life Sciences at the University of Nottingham. She is a world-leading expert on Bdellovibrio bacteriovorus, a species of predatory bacteria.
Karine Gibbs is a Jamaican American microbiologist and immunologist and an associate professor in the Department of Plant and Microbial Biology at the University of California, Berkeley. Gibbs’ research merges the fields of sociomicrobiology and bacterial cell biology to explore how the bacterial pathogen Proteus mirabilis, a common gut bacterium which can become pathogenic and cause urinary tract infections, identifies self versus non-self. In 2013, Gibbs and her team were the first to sequence the genome of P. mirabilis BB2000, the model organism for studying self-recognition. In graduate school at Stanford University, Gibbs helped to pioneer the design of a novel tool that allowed for visualization of the movement of bacterial membrane proteins in real time. In 2020, Gibbs was recognized by Cell Press as one of the top 100 Inspiring Black Scientists in America.
Harry Lee Thompson Mobley, Ph.D, is the Frederick G. Novy Distinguished University Professor of Microbiology and Immunology at the University of Michigan Medical School. His research focused on elucidating the mechanisms by which Gram-negative bacilli that include E. coli, Proteus mirabilis, Klebsiella pneumoniae, Citrobacter freundii, Serratia marcescens, Acinetobacter baumannii, and Helicobacter pylori colonize initial sites of infections that include the urinary tract, the lungs, and the gastrointestinal tract, in some cases, disseminating systemically and entering the bloodstream and the blood-filtering organs including the spleen and liver. For decades, the lab studied urinary tract infection including both “uncomplicated” UTI in otherwise healthy women and “complicated” UTI such as catheter-associated UTI. Bacterial infections of the bladder can ascend to the kidneys and enter renal capillaries to gain access to the bloodstream and infect blood-filtering organs. His research focused on the mechanism by which Gram-negative bacilli colonize the human host, elude the innate immune response, and disseminate from primary sites of infection including the urinary tract into the bloodstream.
Susan Mary Lea is a British biologist who serves as chief of the center for structural biology at the National Cancer Institute. Her research investigates host-pathogen interactions and biomolecular pathways. She was elected a Fellow of the Royal Society in 2022.