John Savill

Last updated

Sir John Savill
Born
John Stewart Savill

(1957-04-25) 25 April 1957 (age 66) [1]
Alma mater University of Oxford (BA) [1]
University of Sheffield (MB ChB)
Royal Postgraduate Medical School (PhD)
Awards
Scientific career
FieldsMedicine
Immunology
Apoptosis
Institutions Hammersmith Hospital
University of Edinburgh
Medical Research Council
University of Oxford
University of Sheffield
Thesis Macrophage recognition of senescent neutrophils  (1989)
Website mrc.ac.uk/about/chief-executive-management-board/

Sir John Stewart Savill, FRS, [2] FMedSci (born 25 April 1957) [1] is the Chief Executive of the Medical Research Council (MRC) in the UK and the Head of the College of Medicine and Veterinary Medicine and a Vice Principal of the University of Edinburgh. [3]

Contents

Education

Savill was educated at St Catherine's College, Oxford and the University of Sheffield [1] where he gained his Bachelor of Medicine, Bachelor of Surgery in 1981 Savill was awarded a PhD for his work on macrophages from the Royal Postgraduate Medical School in 1989. [4]

Research and career

Savill is widely known for his research is on apoptosis and immunology. [5] [6] [7] [8] As of 2016 Savill is active in acute general medicine and is an Honorary Consultant Physician and Nephrologist with the Lothian University Hospitals Division. He is a member of the Lothian Health Board and chairs its Service Redesign Committee.

Savill has extensive experience in peer review and has a particular interest in research and development, and the career structures necessary for this, having chaired the Academy of Medical Sciences Working Party on Clinical Academic Careers.

John Savill's research interests revolve around the role of cell death and macrophages in resolution and repair of inflammation, especially inflammatory disorders of the kidney glomerulus (glomerulonephritis) and interstitium (tubulointerstitial nephritis).

Present [ when? ] roles

Previous roles

Awards and honours

He was appointed Knight Bachelor in the 2008 New Year Honours. [11] He was also elected a Fellow of the Royal Society (FRS) in 2013, [2] awarded Fellowship of the Royal College of Physicians (FRCP),[ when? ] elected a Fellow of the Academy of Medical Sciences (FMedSci) [ when? ] and a Fellow of the Royal Society of Edinburgh (FRSE).[ when? ] He is an honorary member of the British Society for Immunology. [12] In 1999 he was elected a member of the Harveian Society of Edinburgh and in 2009 he served as President of the Society. [13] He was elected a Fellow of the Australian Academy of Health and Medical Sciences in 2021. [14]

Related Research Articles

Anthony Segal FRS FMedSci is a British physician/scientist.

<span class="mw-page-title-main">Kay Davies</span> British geneticist and anatomist; educator

Dame Kay Elizabeth Davies is a British geneticist. She is Dr Lee's Professor of Anatomy at the University of Oxford and a Fellow of Hertford College, Oxford. She is director of the Medical Research Council (MRC) functional genetics unit, a governor of the Wellcome Trust, a director of the Oxford Centre for Gene Function, and a patron and Senior Member of Oxford University Scientific Society. Her research group has an international reputation for work on Duchenne muscular dystrophy (DMD). In the 1980s, she developed a test which allowed for the screening of foetuses whose mothers have a high risk of carrying DMD.

Sir David Keith Peters is a retired Welsh physician and academic. He was Regius Professor of Physic at the University of Cambridge from 1987 to 2005, where he was also head of the School of Clinical Medicine.

Veronica van Heyningen is an English geneticist who specialises in the etiology of anophthalmia as an honorary professor at University College London (UCL). She previously served as head of medical genetics at the MRC Human Genetics Unit in Edinburgh and the president of The Genetics Society. In 2014 she became president of the Galton Institute. As of 2019 she chairs the diversity committee of the Royal Society, previously chaired by Uta Frith.

<span class="mw-page-title-main">Brigitte Askonas</span> British immunologist (1923–2013)

Brigitte Alice Askonas was a British immunologist and a visiting professor at Imperial College London from 1995.

John Andrew Todd FMedSci FRS is Professor of Precision Medicine at the University of Oxford, director of the Wellcome Center for Human Genetics and the JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, in addition to Jeffrey Cheah Fellow in Medicine at Brasenose College. He works in collaboration with David Clayton and Linda Wicker to examine the molecular basis of type 1 diabetes.

<span class="mw-page-title-main">Mark Walport</span> English medical scientist and immunologist

Sir Mark Jeremy Walport is an English medical scientist and was the Government Chief Scientific Adviser in the United Kingdom from 2013 to 2017 and Chief Executive of UK Research and Innovation (UKRI) from 2017 to 2020. In 2023 he became the Foreign Secretary of The Royal Society.

Doreen Ann CantrellCBE, FRS, FRSE, FMedSci is an English scientist and Professor of Cellular Immunology at the School of Life Sciences, University of Dundee. She researches the development and activation T lymphocytes, which are key to the understanding the immune response.

Elizabeth Simpson OBE FRS FMedSci is a British biologist. She is the Emeritus Professor of Transplantation Biology at Imperial College London. Simpson is particularly known for her elucidation of the nature of male-associated minor transplantation antigens, and their roles in the generation of immunological tolerance, graft versus host disease, and transplant rejection.

<span class="mw-page-title-main">Ketan J. Patel</span>

Ketan Jayakrishna Patel is a British-Kenyan scientist who is Director of the MRC Weatherall Institute of Molecular Medicine and the MRC Molecular Haematology Unit at the University of Oxford. Until 2020 he was a tenured principal investigator at the Medical Research Council (MRC) Laboratory of Molecular Biology (LMB).

<span class="mw-page-title-main">Stephen D. M. Brown</span>

Steve David Macleod Brown is director of the Medical Research Council (MRC) Mammalian Genetics Unit, MRC Harwell at Harwell Science and Innovation Campus, Oxfordshire, a research centre on mouse genetics. In addition, he leads the Genetics and Pathobiology of Deafness research group.

Andrew Oliver Mungo Wilkie is a clinical geneticist who has been the Nuffield professor of Pathology at the University of Oxford since 2003.

<span class="mw-page-title-main">Lalita Ramakrishnan</span> Indian-American microbiologist

Lalita Ramakrishnan is an Indian-born American microbiologist who is known for her contributions to the understanding of the biological mechanism of tuberculosis. As of 2019 she serves as a professor of Immunology and Infectious Diseases at the University of Cambridge, where she is also a Wellcome Trust Principal Research Fellow and a practicing physician. Her research is conducted at the MRC Laboratory of Molecular Biology, where she serves as the Head of the Molecular Immunity Unit of the Department of Medicine embedded at the MRC LMB. Working with Stanley Falkow at Stanford, she developed the strategy of using Mycobacterium marinum infection as a model for tuberculosis. Her work has appeared in a number of journals, including Science, Nature, and Cell. In 2018 and 2019 Ramakrishnan coauthored two influential papers in the British Medical Journal (BMJ) arguing that the widely accepted estimates of the prevalence of latent tuberculosis—estimates used as a basis for allocation of research funds—are far too high. She is married to Mark Troll, a physical chemist.

<span class="mw-page-title-main">Neil Gow (scientist)</span> British microbiologist (born 1957)

Neil Andrew Robert Gow is a professor of Microbiology and deputy Vice Chancellor at the University of Exeter. Previously he served at the University of Aberdeen for 38 years and retains an honorary chair there.

<span class="mw-page-title-main">E. Yvonne Jones</span> Director of the Cancer Research UK Receptor Structure Research Group

(Edith) Yvonne JonesFLSW is director of the Cancer Research UK Receptor Structure Research Group at the University of Oxford and a Fellow of Jesus College, Oxford. She is widely known for her research on the molecular biology of cell surface receptors and signalling complexes.

<span class="mw-page-title-main">Andrew N. J. McKenzie</span>

Andrew Neil James McKenzie is a molecular biologist and group leader in the Medical Research Council (MRC) Laboratory of Molecular Biology (LMB).

Charles Bangham holds the Chair in Immunology at Imperial College London.

Caetano Maria Pacheco Pais dos Reis e Sousa is a senior group leader at the Francis Crick Institute and a professor of Immunology at Imperial College London.

<span class="mw-page-title-main">Janet Mary Lord</span> British biologist and academic

Janet Mary Lord is a British biologist who is a Professor of Immune Cell Biology at the University of Birmingham. Her research considers immunity in old age, with a focus on the decline of neutrophil function. She was made a Commander of the British Empire in the 2023 New Year Honours List.

Judith Elizabeth Allen is a British scientist who is Professor of Immunobiology at the University of Manchester. She is an expert on macrophages activated during helminthiasis and was elected Fellow of the Royal Society (FRS) in 2023. She has also done extensive work into type 2 immunity and was awarded Honorary Professor at the University of Edinburgh in 2016.

References

  1. 1 2 3 4 "SAVILL, Sir John Stewart" . Who's Who . Vol. 2013 (online Oxford University Press  ed.). Oxford: A & C Black.(Subscription or UK public library membership required.)
  2. 1 2 3 Anon (2013). "Sir John Savill FMedSci FRS". London: royalsociety.org. Archived from the original on 17 November 2015. One or more of the preceding sentences incorporates text from the royalsociety.org website where:
    "All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License." -- "Royal Society Terms, conditions and policies". Archived from the original on 25 September 2015. Retrieved 9 March 2016.{{cite web}}: CS1 maint: bot: original URL status unknown (link)
  3. John Savill publications indexed by Microsoft Academic
  4. Savill, John (1989). Macrophage recognition of senescent neutrophils (PhD thesis). Royal Postgraduate Medical School. OCLC   940323102.(subscription required)
  5. Savill, J.; Fadok, V.; Henson, P.; Haslett, C. (1993). "Phagocyte recognition of cells undergoing apoptosis". Immunology Today. 14 (3): 131–136. doi:10.1016/0167-5699(93)90215-7. PMID   8385467.
  6. Savill, J.; Dransfield, I.; Gregory, C.; Haslett, C. (2002). "A blast from the past: Clearance of apoptotic cells regulates immune responses". Nature Reviews Immunology. 2 (12): 965–975. doi:10.1038/nri957. PMID   12461569.
  7. Savill, J.; Fadok, V. (2000). "Corpse clearance defines the meaning of cell death". Nature. 407 (6805): 784–788. Bibcode:2000Natur.407..784S. doi:10.1038/35037722. PMID   11048729. S2CID   4410310.
  8. Savill, J. S.; Wyllie, A. H.; Henson, J. E.; Walport, M. J.; Henson, P. M.; Haslett, C. (1989). "Macrophage phagocytosis of aging neutrophils in inflammation. Programmed cell death in the neutrophil leads to its recognition by macrophages". Journal of Clinical Investigation. 83 (3): 865–875. doi:10.1172/JCI113970. PMC   303760 . PMID   2921324.
  9. "New MRC Chief Executive announced". Archived from the original on 4 January 2013. Retrieved 30 November 2012.
  10. "Senior officials 'high earners' salaries as at 30 September 2015 – GOV.UK". gov.uk. 17 December 2015. Retrieved 9 March 2016.
  11. "Dolly creator heads Scots honours". BBC News. 29 December 2007. Retrieved 25 August 2010.
  12. "Honorary members | British Society for Immunology".
  13. Minute Books of the Harveian Society. Library of the Royal College of Physicians of Edinburgh.
  14. "29 new Fellows elected". AAHMS – Australian Academy of Health and Medical Sciences. 26 October 2021. Retrieved 29 October 2021.
Government offices
Preceded by CEO of the Medical Research Council Incumbent