Mark Walport

Last updated

Sir

Mark Walport

FRS FRCP FRCPath FMedSci FRSE
Sir Mark Walport (8656569975) cropped.jpg
Mark Walport
Born
Mark Jeremy Walport

(1953-01-25) 25 January 1953 (age 70) [1]
London, England
Education St Paul's School, London
Alma mater University of Cambridge (PhD) [1]
Known for
Spouse
Julia Elizabeth Neild
​
​
(m. 1986)​
[1]
Childrenone son, three daughters [1]
Awards
Scientific career
Fields Immunology
Rheumatology
Institutions
Thesis The biology of complement receptors  (1986)
Doctoral advisor Peter Lachmann [5]
Website gov.uk/government/people/mark-walport

Sir Mark Jeremy Walport FRS FRCP FRCPath FMedSci FRSE (born 25 January 1953 [1] ) is an English medical scientist and was the Government Chief Scientific Adviser in the United Kingdom from 2013 to 2017 [3] [6] [7] [8] [9] [10] [11] [12] and Chief Executive of UK Research and Innovation (UKRI) from 2017 [13] to 2020. [14] In 2023 he became the Foreign Secretary of The Royal Society (jointly with Alison Noble). [15]

Contents

Education

Walport is the son of a general practitioner and was born in London. He was educated at St Paul's School, London, [1] studied medicine at Clare College, Cambridge, and completed his clinical training at Hammersmith, Guy's and Brompton Hospitals in London. [16] [17] He was awarded a PhD for research into complement receptors under the supervision of Peter Lachmann in 1986 at the University of Cambridge. [18]

Career and research

Previously Walport was Director of the Wellcome Trust from 2003 to 2013. [2] Before this, he was Professor of Medicine (from 1991) and Head of the Division of Medicine (from 1997) at Imperial College London, [16] where he led a research team that focused on the immunology and genetics of rheumatic diseases. [19] [20] [21] [22] [23] [24] [25] [26]

Walport was the eleventh Government Chief Scientific Adviser from 2013 to 2017, succeeding Sir John Beddington.

It was announced in February 2017 that Mark Walport is now Chief Executive of UK Research and Innovation (UKRI). [13]

Honours and awards

Walport was knighted in the 2009 New Year Honours list for services to medical research. He was elected an Honorary Fellow of the Royal Society of Edinburgh (FRSE) in 2017 [27] and a Fellow of the Royal Society (FRS) in 2011. [4] [16] His nomination for the Royal Society reads:

Mark Walport has an overwhelming case for election both for his earlier scientific work on the immunology of systemic LE and the role of complement and of defective apoptosis in its pathogenesis; and, as a general candidate, for his achievements as head of medicine at the Hammersmith Campus of Imperial College and since 2003 as Director of the Wellcome Trust. In the latter role he has provided national and international leadership at the highest level on biomedical research and policy issues and is widely recognised as a world leader in the promotion of biomedical science. [4]

Related Research Articles

<span class="mw-page-title-main">Antonio Damasio</span> Portuguese-American neuroscientist

Antonio Damasio is a Portuguese-American neuroscientist. He is currently the David Dornsife Chair in Neuroscience, as well as Professor of Psychology, Philosophy, and Neurology, at the University of Southern California, and, additionally, an adjunct professor at the Salk Institute. He was previously the chair of neurology at the University of Iowa for 20 years. Damasio heads the Brain and Creativity Institute, and has authored several books: his work, Self Comes to Mind: Constructing the Conscious Brain (2010), explores the relationship between the brain and consciousness. Damasio's research in neuroscience has shown that emotions play a central role in social cognition and decision-making.

<span class="mw-page-title-main">John Gurdon</span> English developmental biologist (born 1933)

Sir John Bertrand Gurdon is a British developmental biologist, best known for his pioneering research in nuclear transplantation and cloning.

Sir Mark Edward Welland, is a British physicist who is a professor of nanotechnology at the University of Cambridge and head of the Nanoscience Centre. He has been a fellow of St John's College, Cambridge, since 1986 and started his career in nanotechnology at IBM Research, where he was part of the team that developed one of the first scanning tunnelling microscopes. He was elected as the master of St Catharine's College, Cambridge and took up office on 1 October 2016.

<span class="mw-page-title-main">Walter Bodmer</span> German-born British human geneticist

Sir Walter Fred Bodmer is a German-born British human geneticist.

<span class="mw-page-title-main">Wellcome Sanger Institute</span> British genomics research institute

The Wellcome Sanger Institute, previously known as The Sanger Centre and Wellcome Trust Sanger Institute, is a non-profit British genomics and genetics research institute, primarily funded by the Wellcome Trust.

<span class="mw-page-title-main">Salvador Moncada</span> Honduran-British pharmacologist and professor

Sir Salvador Enrique Moncada Seidner, FRS, FRCP, FMedSci is a Honduran-British pharmacologist and professor. He is currently Research Domain Director for Cancer at the University of Manchester.

Sir Roy Malcolm Anderson is a leading international authority on the epidemiology and control of infectious diseases. He is the author, with Robert May, of the most highly cited book in this field, entitled Infectious Diseases of Humans: Dynamics and Control. His early work was on the population ecology of infectious agents before focusing on the epidemiology and control of human infections. His published research includes studies of the major viral, bacterial and parasitic infections of humans, wildlife and livestock. This has included major studies on HIV, SARS, foot and mouth disease, bovine tuberculosis, bovine spongiform encephalopathy (BSE), influenza A, antibiotic resistant bacteria, the neglected tropical diseases and most recently COVID-19. Anderson is the author of over 650 peer-reviewed scientific articles with an h-index of 125.

<span class="mw-page-title-main">John Beddington</span> British biologist

Sir John Rex BeddingtonHonFREng is a British population biologist and Senior Adviser at the Oxford Martin School, and was previously Professor of Applied Population Biology at Imperial College London, and the UK Government Chief Scientific Adviser from 2008 until 2013.

Tobias Bonhoeffer is a German-American neurobiologist. He is director of the department Synapses – Circuits – Plasticity and current managing director at the Max Planck Institute for Biological Intelligence. His father, the neurobiologist Friedrich Bonhoeffer, was director at the Max Planck Institute for Developmental Biology in Tübingen.

<span class="mw-page-title-main">Fiona Watt</span> British scientist

Fiona Watt, is a British scientist who is internationally known for her contributions to the field of stem cell biology. In the 1980s, when the field was in its infancy, she highlighted key characteristics of stem cells and their environment that laid the foundation for much present day research. She is currently director of the Centre for Stem Cells & Regenerative Medicine at King's College London, and Executive Chair of the Medical Research Council (MRC), the first woman to lead the MRC since its foundation in 1913. On 13 July 2021 she was appointed as the new Director of the European Molecular Biology Organization (EMBO).

Sir Michael Rudolf Stratton, is a British clinical scientist and the third director of the Wellcome Trust Sanger Institute. He currently heads the Cancer Genome Project and is a leader of the International Cancer Genome Consortium.

<span class="mw-page-title-main">Stephen O'Rahilly</span> Irish-British physician and scientist

Sir Stephen Patrick O'Rahilly is an Irish-British physician and scientist known for his research into the molecular pathogenesis of human obesity, insulin resistance and related metabolic and endocrine disorders.

<span class="mw-page-title-main">Eleanor Maguire</span> Irish neuroscientist (born 1970)

Eleanor Anne Maguire is an Irish neuroscientist. Since 2007, she has been Professor of Cognitive Neuroscience at University College London where she is also a Wellcome Trust Principal Research Fellow.

<span class="mw-page-title-main">Ian L. Boyd</span> British zoologist (born 1957)

Sir Ian Lamont Boyd, is a Scottish zoologist, environmental and polar scientist, former Chief Scientific Adviser at the Department for Environment, Food and Rural Affairs (DEFRA) and is a professor of biology at the University of St Andrews. He is Chair of the UK Research Integrity Office and President of the Royal Society of Biology.

<span class="mw-page-title-main">Gordon Dougan</span>

Gordon Dougan is a Professor in the Department of Medicine at the University of Cambridge and head of pathogen research and a member of the board of management at the Wellcome Sanger Institute in Cambridge, United Kingdom. He is also a Fellow of Wolfson College, Cambridge. During his career, Dougan has pioneered work on enteric diseases and been heavily involved in the movement to improve vaccine usage in developing countries. In this regard he was recently voted as one of the top ten most influential people in the vaccine world by people working in the area.

<span class="mw-page-title-main">Alan Soper</span>

Alan Kenneth Soper FRS is an STFC Senior Fellow at the ISIS neutron source based at the Rutherford Appleton Laboratory in Oxfordshire.

<span class="mw-page-title-main">G. Marius Clore</span> Molecular biophysicist, structural biologist

G. Marius Clore MAE, FRSC, FRS is a British-born, Anglo-American molecular biophysicist and structural biologist. He was born in London, U.K. and is a dual U.S./U.K. Citizen. He is a Member of the National Academy of Sciences, a Fellow of the Royal Society, a NIH Distinguished Investigator, and the Chief of the Molecular and Structural Biophysics Section in the Laboratory of Chemical Physics of the National Institute of Diabetes and Digestive and Kidney Diseases at the U.S. National Institutes of Health. He is known for his foundational work in three-dimensional protein and nucleic acid structure determination by biomolecular NMR spectroscopy, for advancing experimental approaches to the study of large macromolecules and their complexes by NMR, and for developing NMR-based methods to study rare conformational states in protein-nucleic acid and protein-protein recognition. Clore's discovery of previously undetectable, functionally significant, rare transient states of macromolecules has yielded fundamental new insights into the mechanisms of important biological processes, and in particular the significance of weak interactions and the mechanisms whereby the opposing constraints of speed and specificity are optimized. Further, Clore's work opens up a new era of pharmacology and drug design as it is now possible to target structures and conformations that have been heretofore unseen.

Sir Douglass Matthew Turnbull is Professor of Neurology at Newcastle University, an Honorary Consultant Neurologist at Newcastle upon Tyne Hospitals NHS Foundation Trust and a director of the Wellcome Trust Centre for Mitochondrial Research.

<span class="mw-page-title-main">Robin Allshire</span>

Robin Campbell Allshire is Professor of Chromosome Biology at University of Edinburgh and a Wellcome Trust Principal Research Fellow. His research group at the Wellcome Trust Centre for Cell Biology focuses on the epigenetic mechanisms governing the assembly of specialised domains of chromatin and their transmission through cell division.

<span class="mw-page-title-main">Patrick Vallance</span> British medical doctor

Sir Patrick John Thompson Vallance is a British physician, scientist, and clinical pharmacologist who has worked in both academia and industry. He served as the Chief Scientific Adviser to the Government of the United Kingdom from 2018 to 2023.

References

  1. 1 2 3 4 5 6 Anon (2015). "Walport, Sir Mark (Jeremy)" . Who's Who (online Oxford University Press  ed.). A & C Black. doi:10.1093/ww/9780199540884.013.U38753.(Subscription or UK public library membership required.)
  2. 1 2 Vogel, Gretchen (2003). "United Kingdom: Mark Walport to Take Reins at Wellcome Trust". Science. 299 (5608): 803a–. doi:10.1126/science.299.5608.803a. PMID   12574591. S2CID   70581694.
  3. 1 2 Callaway, Ewen (2012). "Britain names next chief science adviser: Immunologist Mark Walport, head of one of the world's largest biomedical charities, will take on role in 2013". Nature. 487 (7405): 20. doi: 10.1038/487020a . PMID   22763530.
  4. 1 2 3 Anon (2011). "Sir Mark Walport". Royal Society . Retrieved 5 July 2012. One or more of the preceding sentences incorporates text from the royalsociety.org website where:
    “All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License.” --Royal Society Terms, conditions and policies at the Wayback Machine (archived 2016-11-11)
  5. ↑ Reed, Tanya (11 July 2003). "Wellcome to a new beginning". Reporter: The newspaper of Imperial College London. No. 131.
  6. ↑ Mayor, S. (2012). "Mark Walport will be next UK government chief scientific adviser, cabinet office announces". BMJ. 345: e4621. doi:10.1136/bmj.e4621. PMID   22767620. S2CID   11529948.
  7. ↑ Kain, K. H. (2010). "Funding scientific discovery: An interview with Sir Mark Walport". Disease Models & Mechanisms. 3 (5–6): 265–267. doi: 10.1242/dmm.005710 . PMID   20427555.
  8. ↑ Anon (2012). "Good advice: The UK government's latest appointment offers hope for British science". Nature. 487 (7405): 5–6. doi: 10.1038/487005b . PMID   22763508.
  9. ↑ Gibney, Elizabeth (29 June 2012). "New chief scientific adviser announced". Times Higher Education .
  10. ↑ Mark Walport's publications indexed by the Scopus bibliographic database. (subscription required)
  11. ↑ Sir Mark Walport in conversation with David Cleevely, Centre for Science and Policy (CSaP) University of Cambridge on YouTube
  12. ↑ Boulton, G.; Rawlins, M.; Vallance, P.; Walport, M. (2011). "Science as a public enterprise: The case for open data". The Lancet. 377 (9778): 1633–1635. doi:10.1016/S0140-6736(11)60647-8. PMID   21571134. S2CID   3048048.
  13. 1 2 "Sir Mark Walport will lead UK Research and Innovation". www.gov.uk (Press release). 2 February 2017. Retrieved 4 July 2017.
  14. ↑ "Dominic Cummings' science obsession: based on fact or fiction?". Times Higher Education (THE). 16 October 2019. Retrieved 25 November 2019.
  15. ↑ "Council". The Royal Society. Retrieved 4 July 2023.
  16. 1 2 3 "Dr Sir Mark Walport". Debrett's . Retrieved 14 February 2012.
  17. ↑ Morris, K. (2003). "Mark Walport". The Lancet . 362 (9382): 498–499. doi:10.1016/S0140-6736(03)14090-1. PMID   12927451. S2CID   10861093.
  18. ↑ Walport, Mark Jeremy (1986). The biology of complement receptors (PhD thesis). University of Cambridge. OCLC   59761908. EThOS   uk.bl.ethos.383309.
  19. ↑ "Mark Walport, PhD, MB. BChir., Member, Scientific Board". Grand Challenges in Global Health. Archived from the original on 27 September 2013. Retrieved 14 February 2012.
  20. ↑ Walport, M.; Foulkes, I.; Weissberg, P.; Morgan, D.; Nebhrajani, S. (2012). "Medical research: No catch to UK charity funding". Nature. 482 (7385): 308. Bibcode:2012Natur.482..308W. doi: 10.1038/482308a . PMID   22337042.
  21. ↑ Collins, P. Y.; Patel, V.; Joestl, S. S.; March, D.; Insel, T. R.; Daar, A. S.; Scientific Advisory Board the Executive Committee of the Grand Challenges on Global Mental Health; Bordin, I. A.; Anderson, E. J.; Dhansay, M.; Phillips, C.; Shurin, R. I.; Walport, W.; Ewart, Y.; Savill, S. E.; Bordin, K.; Costello, S.; Durkin, S.; Fairburn, A.; Glass, A.; Hall, A.; Huang, M. M.; Hyman, V.; Jamison, B. J.; Kaaya, S.; Kapur, P. A.; Kleinman, D. J.; Ogunniyi, W.; Otero-Ojeda, M. A.; Poo, W.; Ravindranath, A. (2011). "Grand challenges in global mental health". Nature. 475 (7354): 27–30. doi:10.1038/475027a. PMC   3173804 . PMID   21734685.
  22. ↑ Yamada, T.; Dautry, A.; Walport, M. (2008). "Ready for avian flu?". Nature. 454 (7201): 162. Bibcode:2008Natur.454..162Y. doi: 10.1038/454162a . PMID   18615064. S2CID   205039550.
  23. ↑ Pickering, M. C.; Warren, J.; Rose, K. L.; Carlucci, F.; Wang, Y.; Walport, M. J.; Cook, H. T.; Botto, M. (2006). "Prevention of C5 activation ameliorates spontaneous and experimental glomerulonephritis in factor H-deficient mice". Proceedings of the National Academy of Sciences. 103 (25): 9649–9654. Bibcode:2006PNAS..103.9649P. doi: 10.1073/pnas.0601094103 . PMC   1476693 . PMID   16769899.
  24. ↑ Brown, J. S.; Hussell, T.; Gilliland, S. M.; Holden, D. W.; Paton, J. C.; Ehrenstein, M. R.; Walport, M. J.; Botto, M. (2002). "The classical pathway is the dominant complement pathway required for innate immunity to Streptococcus pneumoniae infection in mice". Proceedings of the National Academy of Sciences. 99 (26): 16969–16974. Bibcode:2002PNAS...9916969B. doi: 10.1073/pnas.012669199 . PMC   139253 . PMID   12477926.
  25. ↑ Botto, M.; Fong, K. Y.; So, A. K.; Barlow, R.; Routier, R.; Morley, B. J.; Walport, M. J. (1992). "Homozygous hereditary C3 deficiency due to a partial gene deletion". Proceedings of the National Academy of Sciences of the United States of America. 89 (11): 4957–4961. Bibcode:1992PNAS...89.4957B. doi: 10.1073/pnas.89.11.4957 . PMC   49207 . PMID   1350678.
  26. ↑ Taylor, P. R.; Carugati, A.; Fadok, V. A.; Cook, H. T.; Andrews, M.; Carroll, M. C.; Savill, J. S.; Henson, P. M.; Botto, M.; Walport, M. J. (2000). "A Hierarchical Role for Classical Pathway Complement Proteins in the Clearance of Apoptotic Cells in Vivo". Journal of Experimental Medicine. 192 (3): 359–366. doi:10.1084/jem.192.3.359. PMC   2193213 . PMID   10934224.
  27. ↑ "RSE Welcomes 60 New Fellows" (Press release). Royal Society of Edinburgh. 15 February 2017. Retrieved 28 March 2017.
Government offices
Preceded by Government Chief Scientific Adviser
2013−2017		Succeeded by
Chris Whitty
Acting
Cultural offices
Preceded by Director of Wellcome Trust
2003–2013		Succeeded by
This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.