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Established | 1995 |
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Director | Karl Kadler [1] |
Location | |
Affiliations | |
Website | www |
The Wellcome Trust Centre for Cell-Matrix Research at the University of Manchester pursues research into extracellular matrix (ECM) biology and its contribution to human diseases. The Centre was established in 1995 by Mike Grant and is funded by the Wellcome Trust. [2]
The Centre set out with the long-term aims of elucidating the structure and function of extracellular matrices and cell-matrix adhesions, defining the contributions of cell-matrix interactions to human diseases, and developing approaches for preventing and treating these diseases.
The Centre focuses on cellular matrix microenvironment, matrix immunobiology, and mechanobiology of the matrix. [3]
As of 2016 [update] principal investigators in the centre include Judi Allen, Clair Baldock, Christoph Ballestrem, Ray Boot-Handford, Pat Caswell, Tony Day, Andrew Gilmore, Richard Grencis, Tim Hardingham, Martin Humphries, Karl Kadler, Rachel Lennon, Qing-Jun Meng, Chris Miller, Martin Schwartz, Charles Streuli, Joe Swift, Dave Thornton, Mark Travis, Sarah Woolner, Ceri Harrop, Thomas Jowitt, David Knight, Toby Starborg and Egor Zindy. [1]
Sir Walter Fred Bodmer is a German-born British human geneticist.
The Wellcome Sanger Institute, previously known as The Sanger Centre and Wellcome Trust Sanger Institute, is a non-profit British genomics and genetics research institute, primarily funded by the Wellcome Trust.
Osteonectin (ON) also known as secreted protein acidic and rich in cysteine (SPARC) or basement-membrane protein 40 (BM-40) is a protein that in humans is encoded by the SPARC gene.
Dame Kay Elizabeth Davies is a British geneticist. She is Dr Lee's Professor of Anatomy at the University of Oxford and a Fellow of Hertford College, Oxford. She is director of the Medical Research Council (MRC) functional genetics unit, a governor of the Wellcome Trust, a director of the Oxford Centre for Gene Function, and a patron and Senior Member of Oxford University Scientific Society. Her research group has an international reputation for work on Duchenne muscular dystrophy (DMD). In the 1980s, she developed a test which allowed for the screening of foetuses whose mothers have a high risk of carrying DMD.
The Cambridge Biomedical Campus is the largest centre of medical research and health science in Europe. The site is located at the southern end of Hills Road in Cambridge, England. Over 20,000 people work at the site and is home to a number of organisations including: Cambridge University Hospitals NHS Foundation Trust, Royal Papworth Hospital NHS Foundation Trust, AstraZeneca's headquarters, Abcam, the Wellcome Trust, Cancer Research UK, the university's medical school, the UK government's Medical Research Council and has National Institute for Health and Care Research Biomedical Research Centre status. It is an accredited UK academic health science centre.
The School of Biological Sciences is a School within the Faculty Biology, Medicine and Health at The University of Manchester. Biology at University of Manchester and its precursor institutions has gone through a number of reorganizations, the latest of which was the change from a Faculty of Life Sciences to the current School.
The Wellcome – MRC Cambridge Stem Cell Institute at the University of Cambridge is a research centre for the nature and potential medical uses of stem cells. It is located on the Cambridge Biomedical Campus in Cambridge, England.
The School of Biological Sciences is a research-led academic community at the University of East Anglia. It works with partners in industry on a range of activities, including translating research discoveries into products, making knowledge and research expertise available through consultancies, contract research and provision of analytical services, as well as partnering industry in training both undergraduate and postgraduate students.
The Centre for Gene Regulation and Expression, located within the School of Life Sciences, University of Dundee, is a research facility working in the field of gene expression and chromosome biology. Previously part of the Dundee Biocentre and receiving significant Wellcome Trust funding from 1995 onwards, it was awarded Wellcome Trust Centre status in 2008. Professor Tom Owen-Hughes is the Centre’s Director.
(Thomas) Michael Dexter FRS is a British haematologist and director of the Wellcome Trust, from 1998 to 2003.
Richard Olding Hynes FRS is a British biologist, a Howard Hughes Medical Institute Investigator, and the Daniel K. Ludwig Professor for Cancer Research at the Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology. His research focuses on cell adhesion and the interactions between cells and the extracellular matrix, with a particular interest in understanding molecular mechanisms of cancer metastasis. He is well known as a co-discoverer of fibronectin molecules, a discovery that has been listed by Thomson Reuters ScienceWatch as a Nobel Prize candidate.
Sir James Cuthbert Smith is Director of Science at the Wellcome Trust and Senior Group Leader at the Francis Crick Institute.
Sarah Amalia Teichmann is a German scientist who is head of cellular genetics at the Wellcome Sanger Institute and a visiting research group leader at the European Bioinformatics Institute (EMBL-EBI). She serves as director of research in the Cavendish Laboratory, at the University of Cambridge and a senior research fellow at Churchill College, Cambridge.
David Chaim Rubinsztein FRS FMedSci is the Deputy Director of the Cambridge Institute of Medical Research (CIMR), Professor of Molecular Neurogenetics at the University of Cambridge and a UK Dementia Research Institute Professor.
Sir Douglass Matthew Turnbull is Professor of Neurology at Newcastle University, an Honorary Consultant Neurologist at Newcastle upon Tyne Hospitals NHS Foundation Trust and a director of the Wellcome Trust Centre for Mitochondrial Research.
Sir David Ian Stuart is a Medical Research Council Professor of Structural Biology at the Wellcome Trust Centre for Human Genetics at the University of Oxford where he is also a Fellow of Hertford College, Oxford. He is best known for his contributions to the X-ray crystallography of viruses, in particular for determining the structures of foot-and-mouth disease virus, bluetongue virus and the membrane-containing phages PRD1 and PM2. He is also director of Instruct and Life Sciences Director at Diamond Light Source.
Duncan Odom is a research group leader at the German Cancer Research Center (DKFZ) in Heidelberg, and the Cancer Research UK Cambridge Institute at the University of Cambridge. Previously he was as an associate faculty member at the Wellcome Trust Sanger Institute from 2011 to 2018.
Anurag Agrawal is an Indian pulmonologist, medical researcher and the director of the Institute of Genomics and Integrative Biology, a CSIR institution. Known for his studies on lung diseases, Agrawal is a senior fellow of the DBT-Wellcome Trust. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards for his contributions to Medical Sciences in 2014. He is also a recipient of the National Bioscience Award for Career Development of the Department of Biotechnology which he received in 2015.
The Department of Genetics is a department of the University of Cambridge that conducts research and teaching in genetics.
Amit Singh is an Indian microbiologist and an associate professor at the department of microbiology and cell biology of the Indian Institute of Science. A Wellcome-DBT Senior Fellow, Singh is known for his studies on the pathogenesis of Mycobacterium tuberculosis. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development for 2017/18. He was awarded with the prestigious CSIR- Shanti Swarup Bhatnagar award on 2021 for his phenomenal contributions in bio-scientific research. He received the 2021 Shanti Swarup Bhatnagar Prize for Science and Technology in Biological Science.