The Manchester Institute of Biotechnology, formerly the Manchester Interdisciplinary Biocentre (MIB) is a research institute of the University of Manchester, England. The centre has been designed to enable academic communities to explore specific areas of interdisciplinary quantitative bioscience, largely through the efforts of multidisciplinary research teams. Research at MIB follows three broadly defined, interdisciplinary and complementary themes: Biological Mechanism and Catalysis, Molecular Bioengineering, Systems biology.
A research institute or research center is an establishment founded for doing research. Research institutes may specialize in basic research or may be oriented to applied research. Although the term often implies natural science research, there are also many research institutes in the social science as well, especially for sociological and historical research purposes.
The University of Manchester is a public research university in Manchester, England, formed in 2004 by the merger of the University of Manchester Institute of Science and Technology and the Victoria University of Manchester. The University of Manchester is a red brick university, a product of the civic university movement of the late 19th century.
Biology is the natural science that studies life and living organisms, including their physical structure, chemical processes, molecular interactions, physiological mechanisms, development and evolution. Despite the complexity of the science, there are certain unifying concepts that consolidate it into a single, coherent field. Biology recognizes the cell as the basic unit of life, genes as the basic unit of heredity, and evolution as the engine that propels the creation and extinction of species. Living organisms are open systems that survive by transforming energy and decreasing their local entropy to maintain a stable and vital condition defined as homeostasis.
Planning for the institute began late in 1998 and culminated with the official opening on 25 October 2006 of the John Garside Building. The building won "Building of the Year" from Manchester Chamber's Building and Development Committee in 2006 along with Beetham Tower, Manchester.
Professor John Garside is a British chemical engineer who was the last Vice-Chancellor of UMIST.
Beetham Tower is a landmark 47-storey mixed use skyscraper in Manchester, England. Completed in 2006, it is named after its developers, the Beetham Organisation, and was designed by SimpsonHaugh and Partners. The development occupies a sliver of land at the top of Deansgate, hence its elongated plan, and was proposed in July 2003, with construction starting a year later.
The building has featured in several television commercials, notably Injury Lawyers 4u.
The institute was renamed the Manchester Institute of Biotechnology on 1 June 2012, retaining the acronym MIB.
Modelling biological systems is a significant task of systems biology and mathematical biology. Computational systems biology aims to develop and use efficient algorithms, data structures, visualization and communication tools with the goal of computer modelling of biological systems. It involves the use of computer simulations of biological systems, including cellular subsystems, to both analyze and visualize the complex connections of these cellular processes.
Rudolf Aebersold is a Swiss biologist, regarded as a pioneer in the fields of proteomics and systems biology. He has primarily researched techniques for measuring proteins in complex samples, in many cases via mass spectrometry. Ruedi Aebersold is a professor of Systems biology at the Institute of Molecular Systems Biology (IMSB) in ETH Zurich. He was one of the founders of the Institute for Systems Biology in Seattle, Washington, where he previously had a research group.
The DGCR8 microprocessor complex subunit (DiGeorge syndrome chromosomal [or critical] region 8) is a protein that in humans is encoded by the DGCR8 gene. In other animals, particularly the common model organisms Drosophila melanogaster and Caenorhabditis elegans, the protein is known as Pasha. It is a required component of the RNA interference pathway.
James J. Collins is an American bioengineer, and the Termeer Professor of Medical Engineering & Science and Professor of Biological Engineering at MIT. He is one of the founders of the emerging field of synthetic biology, and has made multiple synthetic biology breakthroughs in biotechnology and biomedicine, including paper-based diagnostics for Zika & Ebola and programmable cells that serve as living diagnostics and living therapeutics to detect-and-treat infections, rare genetic metabolic disorders, and inflammatory bowel disease. Collins is also a pioneering researcher in systems biology, having made fundamental discoveries regarding the actions of antibiotics and the emergence of antibiotic resistance.
Dame Janet Maureen Thornton,HonFRSC is a senior scientist at the European Bioinformatics Institute (EBI), part of the European Molecular Biology Laboratory (EMBL). She is one of the world's leading researchers in structural bioinformatics, using computational methods to understand protein structure and function. She was formerly director of the EBI from October 2001 to June 2015, and played a key role in ELIXIR.
Joachim Wilhelm "Jo" Messing was a German-American biologist who was a professor of molecular biology and the fourth director of the Waksman Institute of Microbiology at Rutgers University.
Douglas Bruce Kell is a British biochemist and Professor of Bioanalytical Sciences in the School of Chemistry at the University of Manchester, based in the Manchester Institute of Biotechnology (MIB). He served as Chief Executive Officer (CEO) of the Biotechnology and Biological Sciences Research Council (BBSRC) from 2008-2013.
Aviv Regev is a computational biologist at the Broad Institute of MIT and Harvard, Professor at the Department of Biology at Massachusetts Institute of Technology and Investigator at the Howard Hughes Medical Institute.
Simon N. Powell is a British cancer researcher and radiation oncologist residing in New York City.
Nigel Shaun Scrutton FRSB FRSC is a British biochemist and biotechnology innovator known for his work on enzyme catalysis, biophysics and synthetic biology. He is Director of the Manchester Institute of Biotechnology (MIB), a post he has held since 2010, and Professor of Enzymology and Biophysical Chemistry in the School of Chemistry at the University of Manchester. He is Director of the UK Future Biomanufacturing Research Hub, Director of the Fine and Speciality Chemicals Synthetic Biology Research Centre (SYNBIOCHEM), and Co-founder and Director of the 'fuels-from-biology' company C3 Biotechnologies Ltd.
Balasubramanian Gopal is an Indian structural biologist, molecular biophysicist and a professor at the Molecular Biophysics Unit of the Indian Institute of Science. He is known for his studies on cell wall synthesis in Staphylococcus aureus and is an elected fellow of the National Academy of Sciences, India, Indian National Science Academy and the Indian Academy of Sciences. He received the National Bioscience Award for Career Development of the Department of Biotechnology in 2010. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 2015, for his contributions to biological sciences.
Kanakaraj Sekar is an Indian bioinformatician and a professor at the Department of Computational and Data Sciences of the Indian Institute of Science (IISc). Known for his studies in the field of bioinformatics, Sekar heads the Laboratory for Structural Biology and Bio-computing at IISc. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences in 2004.
Kumaravel Somasundaram is an Indian cancer biologist and a professor at the Department of Microbiology and Cell Biology of the Indian Institute of Science. Known for his studies on the therapeutics of Glioblastoma, Somasunderam is an elected fellow of all the three major Indian science academies namely, the National Academy of Sciences, India, the Indian Academy of Sciences and the Indian National Science Academy. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences in 2006.
Sagar Sengupta is an Indian immunologist, cancer biologist and a scientist at the National Institute of Immunology, India. Known for his studies on tumor suppressor gene and oncogenes, Sengupta is an elected fellow of all the three major Indian science academies namely the National Academy of Sciences, India, the Indian National Science Academy and the Indian Academy of Sciences. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences, in 2011.
Alok Krishna Sinha is an Indian molecular biologist, biochemist, plant physiologist and a staff scientist Grade VII at the National Institute of Plant Genome Research (NIPGR). Known for his research on Mitogen-activated protein kinase (MAPK) cascade in plants, he is a three-time Alexander von Humboldt Fellow and an elected fellow of the National Academy of Sciences, India. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences, in 2013.
The School of Life Sciences at the University of Dundee conducts research into the molecular and cellular mechanisms underlying human health and disease.
Manoj Majee is an Indian plant molecular biologist, biochemist, inventor and a senior scientist at the National Institute of Plant Genome Research (NIPGR), New Delhi. He is known for his studies on the molecular and biochemical basis of seed vigor, longevity and seedling establishment.
Ashwani Kumar is an Indian bacteriologist, biotechnologist and the principal scientist at the Institute of Microbial Technology (ImTech). He is known for his studies on Mycobacterium tuberculosis. The Department of Science and Technology has awarded him Swarnajayanti Fellowship for year 2016-2017. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences, in 2017–18.
Eriko Takano is a professor of synthetic biology and a director of the Synthetic Biology Research Centre for Fine and Speciality Chemicals (SYNBIOCHEM) at the University of Manchester. She develops antibiotics and other high-value chemicals using microbial synthetic biology tools.
Sabine Flitsch is a German organic chemist and chemical biologist who holds a personal chair in Chemical Biology at the University of Manchester School of Chemistry, where she runs an active research glycobiology research group based in the Manchester Interdisciplinary Biocentre.
OpenWetWare is a wiki whose mission is "to support open research, education, publication, and discussion in biological sciences and engineering."
A geographic coordinate system is a coordinate system that enables every location on Earth to be specified by a set of numbers, letters or symbols. The coordinates are often chosen such that one of the numbers represents a vertical position and two or three of the numbers represent a horizontal position; alternatively, a geographic position may be expressed in a combined three-dimensional Cartesian vector. A common choice of coordinates is latitude, longitude and elevation. To specify a location on a plane requires a map projection.
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