LSM7 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | LSM7 , YNL147W, LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 607287 MGI: 1913344 HomoloGene: 6781 GeneCards: LSM7 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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U6 snRNA-associated Sm-like protein LSm7 is a protein that in humans is encoded by the LSM7 gene. [5] [6] [7]
Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM] [7]
LSM7 has been shown to interact with TACC1 [8] [9] and LSM2. [10] [11]
Aurora kinase A also known as serine/threonine-protein kinase 6 is an enzyme that in humans is encoded by the AURKA gene.
Small nuclear ribonucleoprotein-associated proteins B and B' is a protein that in humans is encoded by the SNRPB gene.
SCRIB, also known as Scribble, SCRIBL, or Scribbled homolog (Drosophila), is a scaffold protein which in humans is encoded by the SCRIB gene. It was originally isolated in Drosophila melanogaster in a pathway (also known as the Scribble complex) with DLGAP5 (Discs large) and LLGL1 (Lethal giant larvae) as a tumor suppressor. In humans, SCRIB is found as a membrane protein and is involved in cell migration, cell polarity, and cell proliferation in epithelial cells. There is also strong evidence that SCRIB may play a role in cancer progression because of its strong homology to the Drosophila protein.
Small nuclear ribonucleoprotein G is a protein that in humans is encoded by the SNRPG gene.
U6 snRNA-associated Sm-like protein LSm6 is a protein that in humans is encoded by the LSM6 gene.
U6 snRNA-associated Sm-like protein LSm5 is a protein that in humans is encoded by the LSM5 gene.
U6 snRNA-associated Sm-like protein LSm4 is a protein that in humans is encoded by the LSM4 gene.
U6 snRNA-associated Sm-like protein LSm1 is a protein that in humans is encoded by the LSM1 gene.
U6 snRNA-associated Sm-like protein LSm3 is a protein that in humans is encoded by the LSM3 gene.
Transforming acidic coiled-coil-containing protein 1 is a protein that in humans is encoded by the TACC1 gene.
U6 snRNA-associated Sm-like protein LSm2 is a protein that in humans is encoded by the LSM2 gene.
U6 snRNA-associated Sm-like protein LSm8 is a protein that in humans is encoded by the LSM8 gene.
Cytoskeleton-associated protein 5 is a microtubule-associated protein that in humans is encoded by the CKAP5 gene. It is the homolog of the Xenopus protein XMAP215 and is also known as ch-Tog.
Integrator complex subunit 6 is a protein that in humans is encoded by the INTS6 gene.
Programmed cell death protein 2 is a protein that in humans is encoded by the PDCD2 gene.
U7 snRNA-associated Sm-like protein LSm10 is a protein that in humans is encoded by the LSM10 gene.
Peptidyl-prolyl cis-trans isomerase H is an enzyme that in humans is encoded by the PPIH gene.
Serine/threonine-protein kinase PCTAIRE-2 is an enzyme that in humans is encoded by the PCTK2 gene.
Fms-related tyrosine kinase 4, also known as FLT4, is a protein which in humans is encoded by the FLT4 gene.
Tudor domain-containing protein 7 is a protein that in humans is encoded by the TDRD7 gene.