| Lists of religious leaders by century: |
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This is a list of the top-level leaders for religious groups with at least 50,000 adherents, and that led anytime from January 1, 1501, to December 31, 1600. It should likewise only name leaders listed on other articles and lists.
The Patriarch of Antioch is a traditional title held by the bishop of Antioch. As the traditional "overseer" of the first gentile Christian community, the position has been of prime importance in Pauline Christianity from its earliest period. This diocese is one of the few for which the names of its bishops from the apostolic beginnings have been preserved. Today five churches use the title of patriarch of Antioch: one Eastern Orthodox ; one Oriental Orthodox ; and three Eastern Catholic.
The title His Holiness is an official title or style referring to leaders in a number of religious traditions. It is used to refer to the Pope in Roman Catholicism; this use can be traced back several hundred years. It is also an official title for Oriental Orthodox patriarchs, and used to refer to religious leaders in Islam, Buddhism, and Bon. Buddhist leaders referred to this way include the Dalai Lama, the Menri Trizin, among others; the Da'i al-Mutlaq of the Dawoodi Bohras is one example of a Muslim leader styled this way.
Musta'li Isma'ilism is a branch of Isma'ilism named for their acceptance of al-Musta'li as the legitimate ninth Fatimid caliph and legitimate successor to his father, al-Mustansir Billah. In contrast, the Nizari—the other living branch of Ismailism, presently led by Aga Khan IV—believe the ninth caliph was al-Musta'li's elder brother, Nizar.
Da'i al-Mutlaq is the most senior spiritual rank and office in Tayyibi Isma'ilism. The Da'i al-Mutlaq has headed the Tayyibi community since the seclusion of the 21st Tayyibi Imam, at-Tayyib Abu'l-Qasim, traditionally placed in 528 AH/1134 AD.
Tayyibi Isma'ilism is the only surviving sect of the Musta'li branch of Isma'ilism, the other being the extinct Hafizi branch. Followers of Tayyibi Isma'ilism are found in various Bohra communities: Dawoodi, Sulaymani, and Alavi.
