| Name | Developer | Publisher | Genre(s) | Operating system(s) | Date released |
|---|
| EA Sports FC 24 | EA Vancouver, EA Romania | EA Sports] | Sports | Microsoft Windows | September 29, 2023 |
| EA Sports FC 25 | EA Vancouver, EA Romania | EA Sports | Sports | Microsoft Windows | September 27, 2023 |
| EA Sports PGA Tour | EA Tiburon | EA Sports | Sports | Microsoft Windows | April 7, 2023 |
| EA Sports WRC | Codemasters | EA Sports | Racing | Microsoft Windows | November 3, 2023 |
| Emperor: Battle for Dune | Intelligent Games, Westwood Studios | EA Games | Real-time strategy | Microsoft Windows | June 12, 2001 |
| The Elder Scrolls: Arena | Bethesda Softworks | Bethesda Softworks | Action role-playing | MS-DOS | March 25, 1994 |
| The Elder Scrolls Adventures: Redguard | Bethesda Softworks | Bethesda Softworks | Action role-playing | MS-DOS | November 14, 1998 |
| The Elder Scrolls II: Daggerfall | Bethesda Softworks | Bethesda Softworks | Action role-playing | MS-DOS | August 31, 1996 |
| The Elder Scrolls III: Morrowind | Bethesda Game Studios | Bethesda Softworks | Action role-playing | Microsoft Windows | May 1, 2002 |
| The Elder Scrolls IV: Oblivion | Bethesda Game Studios, 4J Games, Superscape | Bethesda Softworks | Action role-playing | Microsoft Windows | March 20, 2006 |
| The Elder Scrolls V: Skyrim | Bethesda Game Studios | Bethesda Softworks | Action role-playing | Microsoft Windows | November 11, 2011 |
| The Elder Scrolls VI | Bethesda Game Studios | Bethesda Softworks | Action role-playing | Microsoft Windows | TBA |
| The Elder Scrolls Online | ZeniMax Online Studios | Bethesda Softworks | MMORPG | Microsoft Windows, Mac OS X | April 4, 2014 |
| An Elder Scrolls Legend: Battlespire | Bethesda Softworks | Bethesda Softworks | Action role-playing | MS-DOS | November 30, 1997 |
| Elder Sign: Omens | Fantasy Flight Games | Fantasy Flight Games | Adventure, board game | Microsoft Windows, macOS | October 31, 2011 |
| Emily Wants to Play | Shawn Hitchcock | SKH Apps | Survival horror | Microsoft Windows, macOS | December 10, 2015 |
| Empire: Total War | The Creative Assembly, Feral Interactive | Sega, Feral Interactive | RTS | Microsoft Windows, Linux, macOS | March 3, 2009 |
| Empire Earth | Stainless Steel Studios | Sierra Entertainment | RTS | Microsoft Windows | November 12, 2001 |
| Empire Earth II | Mad Doc Software | Vivendi Universal | RTS | Microsoft Windows | April 26, 2005 |
| Empire Earth III | Mad Doc Software | Sierra Entertainment | RTS | Microsoft Windows | November 6, 2007 |
| Empires Apart | Destiny Bit | Slitherine | RTS | Microsoft Windows | March 29, 2018 |
| Enclave | Starbreeze Studios | Vivendi Universal, TopWare Interactive | Action | Microsoft Windows, Xbox | March 10, 2003 |
| Endless Space | Amplitude Studios | Iceberg Interactive | 4X | Microsoft Windows, macOS | July 4, 2012 |
| Epic Battle Fantasy | Matt Roszak | Kupo Games | Role-playing | Microsoft Windows, Linux, macOS | March 1, 2009 |
| Epic Battle Fantasy 2 | Matt Roszak | Kupo Games | Role-playing | Microsoft Windows, Linux, macOS | August 20, 2009 |
| Epic Battle Fantasy 3 | Matt Roszak | Kupo Games | Role-playing | Microsoft Windows, Linux, macOS | September 12, 2010 |
| Epic Battle Fantasy 4 | Matt Roszak | Kupo Games | Role-playing | Microsoft Windows, Linux, macOS | September 12, 2013 |
| Euro Truck Simulator | SCS Software | SCS Software | Simulator | Microsoft Windows | August 29, 2008 |
| Euro Truck Simulator 2 | SCS Software | SCS Software | Simulator | Microsoft Windows, Linux, macOS | October 19, 2012 |
| Europa Universalis | Paradox Development Studio | Strategy First | Grand strategy | Microsoft Windows | March 14, 2000 |
| European Air War | MicroProse | MicroProse | Combat flight simulation | Microsoft Windows | November 3, 1998 |
| Europa Universalis II | Paradox Development Studio | Strategy First, MacPlay, Typhoon Games | Grand strategy | Microsoft Windows, macOS | November 12, 2001 |
| Europa Universalis III | Paradox Development Studio | Paradox Interactive | Grand strategy | Microsoft Windows | January 23, 2007 |
| Europa Universalis IV | Paradox Development Studio | Paradox Interactive | Grand strategy | Microsoft Windows, Linux, macOS | August 13, 2013 |
| Eve Online | CCP Games | CCP Games | Space flight simulator game, MMORPG | Microsoft Windows, macOS | May 6, 2003 |
| Event 0 | Ocelot Society | Ocelot Society | Adventure | Microsoft Windows, macOS | September 14, 2016 |
| Eye of the Beholder | Strategic Simulations, Inc. | TSR, Inc. | Fantasy, RPG | MS-DOS | April 16, 1990 |
| Eye of the Beholder II: The Legend of Darkmoon | Westwood Associates | Strategic Simulations, Inc. | Fantasy, RPG | MS-DOS | December 12, 1991 |
| Eye of the Beholder III: Assault on Myth Drannor | Strategic Simulations, Inc. | Strategic Simulations, Inc. | Fantasy, RPG | MS-DOS | August 3, 1992 |