MARVELD2

MARVELD2
Identifiers
Aliases	MARVELD2 , DFNB49, MARVD2, MRVLDC2, Tric, MARVEL domain containing 2
External IDs	OMIM: 610572; MGI: 2446166; HomoloGene: 27037; GeneCards: MARVELD2; OMA:MARVELD2 - orthologs
Gene location (Human) Chr. Chromosome 5 (human) [1] Band 5q13.2 Start 69,415,065 bp [1] End 69,444,330 bp [1]
Gene location (Mouse) Chr. Chromosome 13 (mouse) [2] Band 13|13 D1 Start 100,732,465 bp [2] End 100,753,479 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in islet of Langerhans gonad duodenum liver rectum mucosa of transverse colon testicle thyroid gland left lobe of thyroid gland right lobe of thyroid gland Top expressed in otic vesicle saccule otic placode Hindgut urothelium conjunctival fornix medullary collecting duct Paneth cell epithelium of small intestine transitional epithelium of urinary bladder More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding Cellular component cytoplasm integral component of membrane plasma membrane basolateral plasma membrane apical plasma membrane cytoplasmic vesicle membrane tricellular tight junction bicellular tight junction cell junction paranodal junction Schmidt-Lanterman incisure Biological process establishment of endothelial barrier cell-cell junction organization hearing bicellular tight junction assembly Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 153562 218518 Ensembl ENSG00000274671 ENSG00000152939 ENSMUSG00000021636 UniProt Q8N4S9 Q3UZP0 RefSeq (mRNA) NM_001038603 NM_001244734 NM_144724 NM_001038602 NM_178410 RefSeq (protein) NP_001033692 NP_001231663 NP_001033691 NP_848497 Location (UCSC) Chr 5: 69.42 – 69.44 Mb Chr 13: 100.73 – 100.75 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

MARVEL domain-containing protein 2 is a protein that in humans is encoded by the MARVELD2 gene. ^{[5] [6]}

References

1. ENSG00000152939 GRCh38: Ensembl release 89: ENSG00000274671, ENSG00000152939 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000021636 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Riazuddin S, Ahmed ZM, Fanning AS, Lagziel A, Kitajiri S, Ramzan K, Khan SN, Chattaraj P, Friedman PL, Anderson JM, Belyantseva IA, Forge A, Riazuddin S, Friedman TB (Dec 2006). "Tricellulin is a tight-junction protein necessary for hearing". Am J Hum Genet. 79 (6): 1040–51. doi:10.1086/510022. PMC   1698716 . PMID   17186462.
6. "Entrez Gene: MARVELD2 MARVEL domain containing 2".

Further reading

• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi: 10.1016/j.cell.2006.09.026 . PMID   17081983. S2CID   7827573.
• Ikenouchi J, Furuse M, Furuse K, et al. (2006). "Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells". J. Cell Biol. 171 (6): 939–45. doi:10.1083/jcb.200510043. PMC   2171318 . PMID   16365161.
• Zhang Y, Wolf-Yadlin A, Ross PL, et al. (2005). "Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules". Mol. Cell. Proteomics. 4 (9): 1240–50. doi: 10.1074/mcp.M500089-MCP200 . PMID   15951569.
• Ramzan K, Shaikh RS, Ahmad J, et al. (2005). "A new locus for nonsyndromic deafness DFNB49 maps to chromosome 5q12.3-q14.1". Hum. Genet. 116 (1–2): 17–22. doi:10.1007/s00439-004-1205-8. PMID   15538632. S2CID   39267757.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.