Moraxella osloensis

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Moraxella osloensis
Scientific classification OOjs UI icon edit-ltr.svg
Domain: Bacteria
Phylum: Pseudomonadota
Class: Gammaproteobacteria
Order: Pseudomonadales
Family: Moraxellaceae
Genus: Moraxella
Species:
M. osloensis
Binomial name
Moraxella osloensis
Bøvre and Henriksen 1967 (Approved Lists 1980)

Moraxella osloensis is a Gram-negative oxidase-positive, aerobic bacterium within the family Moraxellaceae in the gamma subdivision of the purple bacteria. [1]

Contents

Moraxella osloensis is a mutualistic symbiont of the slug-parasitic nematode Phasmarhabditis hermaphrodita . [1] In nature, Phasmarhabditis hermaphrodita vectors M. osloensis into the shell cavity of the slug host in which the bacteria multiply and kill the slug. [1]

Lifecycle

This bacterium has been identified as one of the natural symbionts of a bacteria-feeding nematode, Phasmarhabditis hermaphrodita (Rhabditida: Rhabditidae), which is an endoparasite of slugs, including the slug Deroceras reticulatum [1] (grey garden slug) which is one of the most serious agricultural and garden slug pests. [2]

In nature, bacteria colonize the gut of nematode-infective juveniles which represent a specialized stage of development adapted for survival in the unfavorable environment. [1] The infective juveniles seek out and enter the slug's shell cavity through the posterior mantle region. [1] Once inside the shell cavity, the bacteria are released, and the infective juveniles resume growth, feeding on the multiplying bacteria. [1] The infected slugs die in 4–10 days, and the nematodes colonize the entire carcass and produce next-generation infective juveniles, which leave the carcass to seek a new host. [1] The bacteria are responsible for killing the slugs; nematodes without bacteria do not cause death. [2]

Biochemistry

The lipopolysaccharide, that is an endotoxin, from M. osloensis is a molluscicide for Deroceras reticulatum when applied by injection. [3]

The lethality of these nematodes to slugs has been shown to correlate with the number of M. osloensis cells carried by infective juveniles. [1] Tan and Grewal (2001) [2] demonstrated that the 72-hour-old M. osloensis cultures inoculated into the shell cavity were highly pathogenic to the slug. [1] They further reported that M. osloensis produced an endotoxin which was identified to be a rough type lipopolysaccharide with a molecular weight of 5300 KD, and the purified lipopolysaccharide was toxic to the slug with an estimated 50% lethal dose of 48 μg when injected into the shell cavity. [1]

Infections of humans

Although M. osloensis rarely infects humans, it can sometimes be found in a variety of tissues, where it sometimes causes disease. [4] [5] Antibiotics [ which? ] are usually effective against such infections. [5]

Odor

Moraxella osloensis has been found to be responsible for locker-room smell or shower-curtain odor. [6]

Classification

The species M. osloensis was proposed in 1967; the bacteria which are now considered to be M. osloensis would previously have been considered to be Moraxella nonliquefaciens or Mima polymorpha (var.) oxidans. [5]

See also

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References

This article incorporates CC-BY-2.0 text from the reference. [1]

  1. 1 2 3 4 5 6 7 8 9 10 11 12 An, Ruisheng; Sreevatsan, Srinand; Grewal, Parwinder S (2008). "Moraxella osloensis Gene Expression in the Slug Host Deroceras reticulatum". BMC Microbiology. 8: 19. doi: 10.1186/1471-2180-8-19 . PMC   2266756 . PMID   18226222.
  2. 1 2 3 Tan, L.; Grewal, P. S. (2001). "Pathogenicity of Moraxella osloensis, a Bacterium Associated with the Nematode Phasmarhabditis hermaphrodita, to the Slug Deroceras reticulatum". Applied and Environmental Microbiology. 67 (11): 5010–6. doi:10.1128/AEM.67.11.5010-5016.2001. PMC   93264 . PMID   11679319.
  3. Tan L, Grewal PS (2003). "Characterization of the first molluscicidal lipopolysaccharide from Moraxella osloensis". Applied and Environmental Microbiology. 69 (6): 3646–9. doi:10.1128/aem.69.6.3646-3649.2003. PMC   161526 . PMID   12788774.
  4. Han, Xiang Y.; Tarrand, Jeffrey J. (2004). "Moraxella osloensis Blood and Catheter Infections During Anticancer Chemotherapy: Clinical and Microbiologic Studies of 10 Cases". American Journal of Clinical Pathology. 121 (4): 581–7. doi: 10.1309/QBB3-AVCM-GWA3-K1XK . PMID   15080311.
  5. 1 2 3 Sugarman B, Clarridge J (1982). "Osteomyelitis caused by Moraxella osloensis". Journal of Clinical Microbiology. 15 (6): 1148–9. doi:10.1128/jcm.15.6.1148-1149.1982. PMC   272268 . PMID   7107844.
  6. Kubota, H.; Mitani, A.; Niwano, Y.; Takeuchi, K.; Tanaka, A.; Yamaguchi, N.; Kawamura, Y.; Hitomi, J. (2012). "Moraxella Species Are Primarily Responsible for Generating Malodor in Laundry". Applied and Environmental Microbiology. 78 (9): 3317–24. doi:10.1128/AEM.07816-11. PMC   3346475 . PMID   22367080.

Further reading