Morgan Sheng

PhD Morgan Sheng
Born	(1958-02-23)February 23, 1958 Taipei, Taiwan [ citation needed ]
Education	PhD in molecular genetics
Alma mater	Harvard University
Scientific career
Fields	Synaptic plasticity, neurodegeneration, therapeutics, psychiatric disorders
Institutions	Stanley Center for Psychiatric Research at Broad Institute, McGovern Institute for Brain Research, Massachusetts General Hospital, Harvard Medical School, Genentech, Howard Hughes Medical Institute
Doctoral advisor	Michael E. Greenberg
Notable students	Casper Hoogenraad
Website	Sheng Lab

Morgan Hwa-Tze Sheng is a professor of neurobiology and a Core Institute Member at the Broad Institute, where he is a co-director of the Stanley Center for Psychiatric Research at Broad Institute. ^[1] He is a professor of neuroscience in the Department of Brain and Cognitive Sciences as well as the Menicon Professor of Neuroscience at Massachusetts Institute of Technology. ^[2] He is also an associate member at both The Picower Institute for Learning and McGovern Institute for Brain Research. ^[3] He has served on the editorial boards of Current Opinions in Neurobiology, Neuron , and The Journal of Neuroscience . ^[4]

Education

Sheng received a PhD in molecular genetics from Harvard University.

Career

His postdoc was performed at the University of California, San Francisco. ^[5] Following that, Sheng was an assistant professor and associate professor at the Massachusetts General Hospital and Harvard Medical School, an investigator at the Howard Hughes Medical Institute, ^[6] professor of neuroscience at Massachusetts Institute of Technology, and vice president of neuroscience at Genentech. ^{[7] [8] [9]} His research has focused on pathogenic mechanisms of neurodegenerative diseases and molecular cellular biology of synapses and synaptic plasticity. ^[10]

Honors and awards

Morgan Sheng (left) and Eunjoon Kim (right) speaking together at the IBS Conference on Neuronal and Glial Functions.

• 2023: Member, National Academy of Medicine ^{[11] [12]}
• 2020: Julius Axelrod Prize, Society for Neuroscience ^{[13] [14]}
• 2010: Honorary fellow, University of Oxford Corpus Christi College
• 2009: Fellow, Academy of Medical Sciences ^[15]
• 2007: Fellow, Royal Society ^[16]
• 2006: Neuronal Plasticity Prize, Fondation IPSEN
• 2005: Outstanding Achievement Award, Neuroscience Division, Society of Chinese Bioscientists in America
• 2004: Fellow, American Association for the Advancement of Science
• 1999: Young Investigator Award, Society for Neuroscience
• 1995: Member, Society for Neuroscience

Selected publications

• Sheng, Morgan; Greenberg, Michael E. (1 April 1990). "The regulation and function of c-fos and other immediate early genes in the nervous system" . Neuron . 4 (4). Cell Press: 477–485. doi:10.1016/0896-6273(90)90106-P. PMID   1969743 . Retrieved 1 November 2023.
• Kim, Eunjoon; Sheng, Morgan (1 October 2004). "PDZ domain proteins of synapses" . Nature Reviews Neuroscience . 5 (10): 771–781. doi:10.1038/nrn1517. PMID   15378037 . Retrieved 1 November 2023.
• Sheng, Morgan; Thompson, Margaret A.; Greenberg, Michael E. (7 June 1991). "CREB: a Ca2+-Regulated Transcription Factor Phosphorylated by Calmodulin-Dependent Kinases" . Science . 252 (5011): 1427–1430. doi:10.1126/science.1646483. PMID   1646483 . Retrieved 1 November 2023.
• Morgan, Sheng; Cummings, Jennifer; Roldan, Leslie Ann; Jan, Yuh Nung; Jan, Lily Yeh (10 March 1994). "Changing subunit composition of heteromeric NMDA receptors during development of rat cortex" . Nature . 368 (6467). Nature Publishing Group UK: 144–147. doi:10.1038/368144a0. PMID   8139656 . Retrieved 1 November 2023.
• Li, Zheng; Okamoto, Ken-Ichi; Hayashi, Yasunori; Sheng, Morgan (17 December 2004). "The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses". Cell . 119 (6). Elsevier: 873–887. doi: 10.1016/j.cell.2004.11.003 . PMID   15607982.

See also

• Paul Blainey
• Feng Zhang
• Eunjoon Kim
• Steven Hyman

References

1. "Morgan Sheng, M.D., Ph.D." Broad Institute. 2 May 2019. Retrieved 1 November 2023.
2. "Morgan Sheng". Nature Reviews Drug Discovery . 8 (10): 766. 2009. doi:10.1038/nrd3014. PMID   19794439 . Retrieved 1 November 2023.
3. "About". Broad Institute . Retrieved 1 November 2023.
4. "Strategic & Scientific Advisors". Cure Shark. Retrieved 1 November 2023.
5. "Co-Director of the Stanley Center for Psychiatric Research at the Broad Institute of MIT and Harvard". Vanqua Bio. Retrieved 1 November 2023.
6. "Morgan Sheng" (PDF). Cell . 27 June 2018. Retrieved 1 November 2023.
7. "Morgan Sheng" . Nature Reviews Drug Discovery . 17 (2): 88–89. 19 January 2018. doi:10.1038/nrd.2017.271. PMID   29348680 . Retrieved 1 November 2023.
8. "Morgan Sheng, Ph.D." Simons Foundation. 21 July 2017. Retrieved 1 November 2023.
9. "Morgan Sheng Appointed VP Neuroscience Research at Genentech". BioPharm. 8 October 2008. Retrieved 1 November 2023.
10. "Morgan Sheng". Picower Institute for Learning and Memory. Massachusetts Institute of Technology . Retrieved 1 November 2023.
11. "Twelve with MIT ties elected to the National Academy of Medicine for 2023". MIT News. Massachusetts Institute of Technology. 10 October 2023. Retrieved 1 November 2023.
12. "National Academy of Medicine Elects 100 New Members". National Academy of Sciences . 9 October 2023. Retrieved 1 November 2023.
13. Tristan Davies (27 October 2020). "Morgan Sheng wins Julius Axelrod Prize for distinguished achievements in neuropharmacology". Department of Brain and Cognitive Sciences. Massachusetts Institute of Technology . Retrieved 1 November 2023.
14. "Society for Neuroscience Presents Julius Axelrod Prize to Morgan Sheng". Society for Neuroscience . 26 October 2020. Retrieved 1 November 2023.
15. "Fellow: Professor Morgan Sheng FRS FMedSci". Academy of Medical Sciences . 2009. Retrieved 1 November 2023.
16. "Fellowship of the Royal Society 1660–2015". London: Royal Society. Archived from the original on 2015-10-15.

External links

• A Mind for the Brain, Genentech
• UC Davis/NIH NeuroMab Facility Advisory Board