This article has multiple issues. Please help improve it or discuss these issues on the talk page . (Learn how and when to remove these messages)
|
Nial J. Wheate | |
---|---|
Born | 1976 Werribee, Victoria, Australia |
Nationality | Australian |
Alma mater | University of New South Wales |
Scientific career | |
Fields | Chemistry |
Institutions | University of Sydney University of Strathclyde University of Western Sydney |
Doctoral advisor | J. Grant Collins |
Nial J. Wheate (born 1976) is an Australian pharmaceutical chemist and author at the University of Sydney.
After completing high school at Copland College in Canberra, Australia, Wheate was appointed as an officer in the Royal Australian Navy. He attended the Australian Defence Force Academy, [1] where he studied for a Bachelor of Science degree, double majoring in chemistry, and graduated in 1997 with Honours Class I. After a short appointment as a Visiting Military Scholar, Wheate undertook a PhD under the supervision of Associate Professor J. Grant Collins within the School of Physical, Environmental and Mathematical Sciences, at University College, University of New South Wales, with a thesis "Platinum Anticancer Drugs" in 2001. [2]
Over the next three years Wheate was posted to the School of Air Navigation (now the School of Air Combat), RAAF Base East Sale, the Air Coordination and Policy Agency, the Joint Health Support Agency, and the Sea Power Centre – Australia. [3] He left the navy in 2005. He was then appointed a Senior Fellow in the School of Biomedical and Health Sciences at the University of Western Sydney before his appointment as a lecturer in medicinal chemistry at the Strathclyde Institute of Pharmacy and Biomedical Sciences at the University of Strathclyde in Glasgow, Scotland. He is an Associate Professor in the Faculty of Medicine and Health at the University of Sydney. In 2013 he was appointed the Head of Cancer Research within the Faculty of Pharmacy. [4] In March 2019, Wheate was appointed to the board of Canngea Pty Ltd, an Australian medicinal cannabis manufacturer, as Science Director.
Wheate's research interests lie in the field of metal-based drugs. His research group's work includes drug design and synthesis, encapsulation of drugs in macrocycles, attachment of drugs to nanoparticles, drug solid-state stability and polymorphism (materials science), drug mechanisms of action, improving drug solubility through the formation of cocrystals, drug metabolism, drug pre-formulation and formulation, and drug-excipient interactions in various dosage forms. Recent highlighted work has included the development of magnetically directed drug delivery for platinum drugs. [5]
Wheate's work has focused on multinuclear platinum-based drugs [6] and the potential applications of cucurbiturils for drug delivery. [7]
In 2013 Wheate was elected Fellow of the Royal Australian Chemical Institute in recognition of his achievements in cancer research [8] and is also a Fellow of the Higher Education Academy.
Wheate was previously an associate editor of the Australian Journal of Chemistry and is a current editor of the Source Journal of Pharmaceutical Science.
Wheate has also published in a variety of other areas including military justice, [9] naval history, [10] [11] weapons of mass destruction [12] and he has written a novel titled Whikatak Island. [13]
Platinum is a chemical element; it has symbol Pt and atomic number 78. It is a dense, malleable, ductile, highly unreactive, precious, silverish-white transition metal. Its name originates from Spanish platina, a diminutive of plata "little silver".
The Royal Australian Navy (RAN) is the naval branch of the Australian Defence Force (ADF). The professional head of the RAN is Chief of Navy (CN) Vice Admiral Mark Hammond AM, RAN. The Chief of Navy is also jointly responsible to the Minister for Defence (MINDEF) and the Chief of the Defence Force (CDF). The Department of Defence, which is a part of the Australian Public Service, administers the ADF, and ergo, the Royal Australian Navy. In 2023, the Surface Fleet Review was introduced to outline the future of the Navy.
Pharmacy is the science and practice of discovering, producing, preparing, dispensing, reviewing and monitoring medications, aiming to ensure the safe, effective, and affordable use of medicines. It is a miscellaneous science as it links health sciences with pharmaceutical sciences and natural sciences. The professional practice is becoming more clinically oriented as most of the drugs are now manufactured by pharmaceutical industries. Based on the setting, pharmacy practice is either classified as community or institutional pharmacy. Providing direct patient care in the community of institutional pharmacies is considered clinical pharmacy.
The UCL School of Pharmacy is the pharmacy school of University College London (UCL). The School forms part of UCL's Faculty of Life Sciences and is located in London, United Kingdom.
Cisplatin is a chemical compound with formula cis-[Pt(NH3)2Cl2]. It is a coordination complex of platinum that is used as a chemotherapy medication used to treat a number of cancers. These include testicular cancer, ovarian cancer, cervical cancer, bladder cancer, head and neck cancer, esophageal cancer, lung cancer, mesothelioma, brain tumors and neuroblastoma. It is given by injection into a vein.
The Royal Australian Chemical Institute (RACI) is both the qualifying body in Australia for professional chemists and a learned society promoting the science and practice of chemistry in all its branches. The RACI hosts conferences, seminars and workshops. It is the professional body for chemistry in Australia, with the ability to award the status of Chartered Chemist (CChem) to suitably qualified candidates.
Monash University, Parkville campus is a campus of Monash University, located in Parkville, Victoria, Australia. It is home to the Faculty of Pharmacy and Pharmaceutical Sciences. Founded in 1881 and previously known as the Victorian College of Pharmacy, the faculty is the oldest school of pharmacy in Australia. A major centre of research and teaching, it is internationally regarded for its research in drug target biology and discovery, medicinal chemistry, drug development, formulation science, and medicine use and safety, including the discovery and development of the world's first successful anti-influenza drug, Relenza. In international rankings, it is ranked as the number one school of pharmacy and pharmacology in Australia and number two worldwide.
The Australian Patrol Boat Group is a Force Element Group (FEG) of the Royal Australian Navy. It manages the Navy's patrol boats.
Australia was a member of the international coalition which contributed military forces to the 1991 Gulf War, also known as Operation Desert Storm. More than 1,800 Australian Defence Force (ADF) personnel were deployed to the Persian Gulf from August 1990 to September 1991, while contingents from the Royal Australian Navy circulated through the region in support of the sanctions against Iraq until November 2001. In August 1990, two frigates HMAS Adelaide and HMAS Darwin and the replenishment ship HMAS Success left for the Persian Gulf. HMAS Success had no air defences, so the Army 16th Air Defence Regiment was embarked. On 3 December 1990, HMAS Brisbane and HMAS Sydney (IV) relieved HMAS Adelaide and HMAS Darwin. On 26 January 1991, HMAS Westralia replaced HMAS Success. A Navy clearance diving team was also deployed for explosive ordnance disposal and demolition tasks. Australian ships were in danger of sea mines and possible air attacks. In a number of recorded incidents, HMAS Brisbane encountered free floating mines, on one occasion narrowly avoiding a collision. Both HMA Ships Brisbane and Sydney encountered significant air threat warnings from Iran and Iraq throughout the initial period of the commencement of the Desert Storm Campaign. The detection of land based Silkworm anti-ship missiles from Iran throughout the campaign also added to the challenges for both crews as well as the multi-national Naval Forces.
The Australian Defence Organisation (ADO) is composed of the armed forces of the Commonwealth of Australia, the Australian Defence Force (ADF), and the Australian Public Service government department, the Department of Defence which is composed of a range of civilian support organisations.
Rear Admiral Nigel Stephen Coates, was a senior officer in the Royal Australian Navy.
Captain Trevor Jackson is an Australian technical diver, shipwreck researcher, author and inventor. In 2002 he staged what became known as the "Centaur Dive", which subsequently led to the gazetted position of the sunken Hospital Ship AHS Centaur being questioned. Jackson is the inventor of the 'Sea Tiger' lost diver location system, and an author on the subject of wreck diving.
Picoplatin is a platinum-based antineoplastic agent in clinical development by Poniard Pharmaceuticals for the treatment of patients with solid tumors.
Rosetta Martiniello-Wilks is an Australian cancer researcher. She is a former senior lecturer at the University of Technology Sydney (UTS) in Ultimo, Sydney, Australia. Martiniello-Wilks was a core member of the Centre for Health Technologies at UTS and head of the Translational Cancer Research Group in the School of Medical and Molecular Biosciences, Faculty of Science, UTS.
Aliasger K. Salem is the Associate Vice President for Research at the University of Iowa and Bighley Chair and Professor of Pharmaceutical Sciences at the University of Iowa College of Pharmacy. Salem's academic appointment at the University of Iowa is based in the College of Pharmacy, with additional secondary appointments in the College of Dentistry, Department of Chemical and Biochemical Engineering, Department of Biomedical Engineering, Department of Chemistry, and the Holden Comprehensive Cancer Center. Prior to joining the University of Iowa in 2004, he was a postdoctoral fellow at the Johns Hopkins School of Medicine and completed his PhD at the School of Pharmacy and Pharmaceutical Sciences at the University of Nottingham in the UK.
Tamara Minko is a distinguished professor and chair of the department of pharmaceutics at Rutgers University, Ernest Mario School of Pharmacy. She has an H-index of 43 since 2016 and over 17,800 citations of her work.
The Navy Headquarters is the command responsible for training, personnel, resources, engineering and capability development of the Royal Australian Navy. As such Navy Headquarters works with the Capability Acquisition and Sustainment Group, the Defence Science and Technology Group, and the Joint Capabilities Group to ensure the personal, materiel and logistical capabilities of the Royal Australian Navy.
The Joint Health Command (JHC) is responsible for the delivery of military medicine and joint healthcare services to Australian Defence Force (ADF) personnel, including military psychiatry and rehabilitation services. The JHC is also responsible for providing strategic health policy, the development of the health preparedness of ADF personnel for operations, and the coordination of health units for deployment in support of operations. JHC is led by the dual-hatted Commander Joint Health and Surgeon General of the ADF.
The 2018 Australia Day Honours are appointments to various orders and honours to recognise and reward good works by Australian citizens. The list was announced on 26 January 2018 by the Governor General of Australia, Sir Peter Cosgrove.
{{cite web}}
: CS1 maint: multiple names: authors list (link){{cite web}}
: CS1 maint: archived copy as title (link){{cite web}}
: CS1 maint: archived copy as title (link) The chemical, biological, radiological and nuclear threat, Papers in Australian Maritime Affairs, 2006, 19, 71-76.