Nial J. Wheate

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Nial J. Wheate
Nial J. Wheate.jpg
Wheate in 2022
Born1976 (age 48–49)
Werribee, Victoria, Australia
NationalityAustralian
Alma mater University of New South Wales
Scientific career
Fields Chemistry
Institutions University of Sydney
University of Strathclyde
University of Western Sydney
Doctoral advisor J. Grant Collins

Nial J. Wheate (born 1976) is an Australian pharmaceutical chemist and author who works at the University of Sydney in Australia. [1]

Contents

Career

After graduating from Copland College in Canberra, Wheate was commissioned as an officer in the Royal Australian Navy. [2] He received a Bachelor of Science degree with a double major in chemistry from the Australian Defence Force Academy, graduating in 1997 with First Class Honours. Following a brief appointment as a Visiting Military Scholar, he completed a PhD in 2001 under the supervision of Associate Professor J. Grant Collins at the University of New South Wales' School of Physical, Environmental, and Mathematical Sciences. His thesis was titled Platinum Anticancer Drugs. [3]

He was later assigned to the School of Air Combat at RAAF Base East Sale. He was accepted into the Air Coordination and Policy Agency, the Joint Health Support Agency, and the Sea Power Centre – Australia. He left the Navy in 2005 and was appointed a Senior Fellow in the School of Biomedical and Health Sciences at the University of Western Sydney. He later became a lecturer in medicinal chemistry at the Strathclyde Institute of Pharmacy and Biomedical Sciences at the University of Strathclyde in Glasgow, Scotland. He is an Associate Professor in the Faculty of Medicine and Health at the University of Sydney. In 2013, he was appointed Head of Cancer Research within the Faculty of Pharmacy. In March 2019, he joined the board of Canngea Pty Ltd, an Australian medicinal cannabis manufacturer, as Science Director.[ citation needed ]

Research Interests

Wheate's research focuses on metal-based drugs. His research group's work includes drug design and synthesis, encapsulation of drugs in macrocycles, attachment of drugs to nanoparticles, drug solid-state stability and polymorphism (materials science), drug mechanisms of action, improving drug solubility through the formation of cocrystals, drug metabolism, drug pre-formulation and formulation, and drug-excipient interactions in various dosage forms. His work has included the development of magnetically directed drug delivery for platinum drugs. [4]

Wheate's work has focused on multinuclear platinum-based drugs [5] and the potential applications of cucurbiturils for drug delivery. [6]

In 2013, Wheate was elected a Fellow of the Royal Australian Chemical Institute in recognition of his work in cancer research [7] and is also a senior fellow of the Higher Education Academy. [8]

Wheate was previously an associate editor of the Australian Journal of Chemistry .[ citation needed ]

Other contributions

Wheate has also published in a variety of other areas, including military justice, [9] naval history, [10] [11] weapons of mass destruction, [12] and he has written a novel titled Whikatak Island. [13]

References

  1. ↑ "Nial Wheate". The Conversation. 21 June 2013. Retrieved 13 April 2025.
  2. ↑ "Nial Wheate". Macquarie University. Retrieved 23 March 2025.
  3. ↑ Wheate, Nial J.; Walker, Shonagh; Craig, Gemma E.; Oun, Rabbab (25 August 2010). "The status of platinum anticancer drugs in the clinic and in clinical trials" . Dalton Transactions. 39 (35): 8113–8127. doi:10.1039/C0DT00292E. hdl:2123/9269. ISSN   1477-9234. PMID   20593091.
  4. ↑ Browne, Rachel (16 June 2012). "Magnets that mark cancer". The Sydney Morning Herald. Archived from the original on 18 June 2012. Retrieved 26 September 2024.
  5. ↑ Wheate, N. (2003). "Multi-nuclear platinum complexes as anti-cancer drugs". Coordination Chemistry Reviews. 241 (1–2): 133–145. doi:10.1016/S0010-8545(03)00050-X.
  6. ↑ Walker, Shonagh; Oun, Rabbab; McInnes, Fiona J.; Wheate, Nial J. (2011). "The Potential of Cucurbit[n]urils in Drug Delivery". Israel Journal of Chemistry. 51 (5–6): 616–624. doi:10.1002/ijch.201100033.
  7. ↑ "Archived copy" (PDF). Archived from the original (PDF) on 4 March 2015. Retrieved 18 January 2015.{{cite web}}: CS1 maint: archived copy as title (link)
  8. ↑ "A/Prof Nial Wheate". Healthed. Retrieved 14 October 2024.
  9. ↑ "Lawful Dissent and the Modern Australian Defence Force" (PDF). Australian Defence Force Journal. 160: 20–30. 2003. Archived from the original (PDF) on 9 October 2011. Retrieved 30 August 2011.
  10. ↑ http://www.defence.gov.au/publications/dfj/ADFJ160.pdf Lawful Dissent and the Modern Australian Defence Force database of Royal Australian Navy Operations 1990-2005.
  11. ↑ http://www.navy.gov.au/Publication:Papers_in_Australian_Maritime_Affairs_No._16 Archived 8 August 2011 at the Wayback Machine Borneo 1945 – An amphibious success story, Paper in Australian Maritime Affairs, 2005, 16, p 139.
  12. ↑ "Archived copy" (PDF). Archived from the original (PDF) on 13 June 2011. Retrieved 12 May 2010.{{cite web}}: CS1 maint: archived copy as title (link) The chemical, biological, radiological and nuclear threat, Papers in Australian Maritime Affairs, 2006, 19, 71-76.
  13. ↑ Wheate, Nial (17 May 2018). "Whikatak Island". Writers Club Press – via National Library of Australia (new catalog).
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