Nocardia farcinica

Last updated

Nocardia farcinica
Scientific classification
Domain:
Phylum:
Class:
Order:
Family:
Genus:
Species:
N. farcinica
Binomial name
Nocardia farcinica
Trevisan 1889 [1]

Nocardia farcinica is a species of bacteria and a member of the genus Nocardia . This species is very similar in phenotype to Nocardia asteroides , to the degree that some isolates of N. asteroides were later found to be Nocardia farcinica. [2]

Contents

Pathogenicity

N. farcinica may be a causative agent of nocardiosis [3] or of secondary infections in immunocompromised patients. [4] Strains of this species have been isolated from human brain abscesses. [5]

Genome

N. farcinica contains a 6 million base pair genome with an average GC content of 70.8%. A sequenced strain, IFM 10152, is also known to contain two plasmids, pNF1 pNF2. The chromosome encodes 5,674 potential protein-coding open reading frames. This genome may have undergone numerous gene duplication events as a result of adapting to new environments. [6]

Related Research Articles

Brain abscess Medical condition

Brain abscess is an abscess caused by inflammation and collection of infected material, coming from local or remote infectious sources, within the brain tissue. The infection may also be introduced through a skull fracture following a head trauma or surgical procedures. Brain abscess is usually associated with congenital heart disease in young children. It may occur at any age but is most frequent in the third decade of life.

Mycoplasma hominis is a species of bacteria in the genus Mycoplasma. M. hominis has the ability to penetrate the interior of human cells. Along with ureaplasmas, mycoplasmas are the smallest free-living organisms known.

<i>Acinetobacter</i> Genus of bacteria

Acinetobacter is a genus of Gram-negative bacteria belonging to the wider class of Gammaproteobacteria. Acinetobacter species are oxidase-negative, exhibit twitching motility, and occur in pairs under magnification.

Nocardiosis is an infectious disease affecting either the lungs or the whole body. It is due to infection by a bacterium of the genus Nocardia, most commonly Nocardia asteroides or Nocardia brasiliensis.

<i>Actinomyces</i> Genus of bacteria

Actinomyces is a genus of the Actinobacteria class of bacteria. They all are Gram-positive. Actinomyces species are facultatively anaerobic, and they grow best under anaerobic conditions. Actinomyces species may form endospores, and while individual bacteria are rod-shaped, Actinomyces colonies form fungus-like branched networks of hyphae. The aspect of these colonies initially led to the incorrect assumption that the organism was a fungus and to the name Actinomyces, "ray fungus".

<i>Nocardia</i> Genus of bacteria

Nocardia is a genus of weakly staining Gram-positive, catalase-positive, rod-shaped bacteria. It forms partially acid-fast beaded branching filaments. It contains a total of 85 species. Some species are nonpathogenic, while others are responsible for nocardiosis. Nocardia species are found worldwide in soil rich in organic matter. In addition, they are oral microflora found in healthy gingiva, as well as periodontal pockets. Most Nocardia infections are acquired by inhalation of the bacteria or through traumatic introduction.

<i>Chromobacterium violaceum</i> Species of bacterium

Chromobacterium violaceum is a Gram-negative, facultative anaerobic, non-sporing coccobacillus. It is motile with the help of a single flagellum which is located at the pole of the coccobacillus. Usually, there are one or two more lateral flagella as well. It is part of the normal flora of water and soil of tropical and sub-tropical regions of the world. It produces a natural antibiotic called violacein, which may be useful for the treatment of colon and other cancers. It grows readily on nutrient agar, producing distinctive smooth low convex colonies with a dark violet metallic sheen. Some strains of the bacteria which do not produce this pigment have also been reported. It has the ability to break down tarballs.

<i>Mycobacterium abscessus</i> Species of bacterium

Mycobacterium abscessus complex (MABSC) is a group of rapidly growing, multidrug-resistant, nontuberculous mycobacteria (NTM) species that are common soil and water contaminants. Although M. abscessus complex most commonly causes chronic lung infection and skin and soft tissue infection (SSTI), the complex can also cause infection in almost all human organs, mostly in patients with suppressed immune systems. Amongst NTM species responsible for disease, infection caused by M. abscessus complex are more difficult to treat due to antimicrobial drug resistance.

Capnocytophaga is a genus of Gram-negative bacteria. Normally found in the oropharyngeal tract of mammals, they are involved in the pathogenesis of some animal bite wounds and periodontal diseases.

<i>Nocardia asteroides</i> Species of bacterium

Nocardia asteroides is a species of Nocardia. It can cause nocardiosis, a severe pulmonary infection in immunocompromised hosts.

Streptococcus intermedius is an aerotolerant anaerobic commensal bacterium and a member of the Streptococcus anginosus group. The S. anginosus group, occasionally termed “Streptococcus milleri group” (SMG) display hemolytic and serologic diversity, yet share core physiological traits. Despite being commensal organisms, members of the S. anginosus group display wide pathogenic potential. S. intermedius has been isolated from patients with periodontitis and fatal purulent infections, especially brain and liver abscesses.

<i>Streptococcus anginosus</i> Species of bacterium

Streptococcus anginosus is a species of Streptococcus. This species, Streptococcus intermedius, and Streptococcus constellatus constitute the anginosus group, which is sometimes also referred to as the milleri group after the previously assumed but later refuted idea of a single species Streptococcus milleri. Phylogenetic relatedness of S. anginosus, S. constellatus, and S. intermedius has been confirmed by rRNA sequence analysis.

Rothia dentocariosa is a species of Gram-positive, round- to rod-shaped bacteria that is part of the normal community of microbes residing in the mouth and respiratory tract.

Lactococcus garvieae is a known fish pathogen affecting saltwater fish in the Far East, specifically in rainbow trout, Japanese yellowtail, and grey mullet. This bacteria causes lesions in the vascular endothelium, leading to hemorrhages and petechias at the surface of internal organs. As few as 10 bacterial cells per fish can cause an infection. L. garvieae is isolated in saltwater fish in the Far East and specifically in European Rainbow Trout.

<i>Achromobacter xylosoxidans</i> Species of bacterium

Achromobacter xylosoxidans is a Gram-negative, aerobic, oxidase and catalase-positive, motile bacterium with peritrichous flagella, from the genus Achromobacter. It is generally found in wet environments. Achromobacter xylosoxidans can cause infections such as bacteremia, especially in patients with cystic fibrosis. In 2013, the complete genome of an A. xylosoxidans strain from a patient with cystic fibrosis was sequenced.

Brucella intermedia is a bacterium from the genus of Brucella. It was first described by Velasco and others in 1998. It causes diseases in humans only rarely, with single case reports of cholangitis following liver transplantation, bacteremia in a patient with bladder cancer, a pelvic abscess after abdominal surgery, dyspepsia, endophalmitis in the presence of a foreign body, pneumonia, and endocarditis.

Anaerococcus is a genus of bacteria. Its type species is Anaerococcus prevotii. These bacteria are Gram-positive and strictly anaerobic. The genus Anaerococcus was proposed in 2001. Its genome was sequenced in August 2009. The genus Anaerococcus is one of six genera classified within the group GPAC. These six genera are found in the human body as part of the commensal human microbiota.

<i>Rhinocladiella mackenziei</i> Species of fungus

Rhinocladiella mackenziei is a deeply pigmented fungus that is a common cause of human cerebral phaeohyphomycosis. Rhinocladiella mackenziei was believed to be endemic solely to the Middle East, due to the first cases of infection being limited to the region. However, cases of R. mackenziei infection are increasingly reported from regions outside the Middle East. This pathogen is unique in that the majority of cases have been reported from immunologically normal people.

Trichosporon asteroides Fungus of the genus Trichosporon

Trichosporon asteroides is an asexual Basidiomycetous fungus first described from human skin but is now mainly isolated from blood and urine. T. asteroides is a hyphal fungus with a characteristically yeast-like appearance due to the presence of slimy arthroconidia. Infections by this species usually respond to treatment with azoles and amphotericin B.

<i>Corynebacterium striatum</i> Species of bacterium

Corynebacterium striatum is a bacterium that is a member of the Corynebacterium genus. It is classified as non-diphtheritic. The bacterium is a gram-positive prokaryote that assumes a 'club-like' morphology, more formally known as a corynebacteria structure. It is non-lipophilic and undergoes aerobic respiration and is also a facultative anaerobe it is catalase negative and oxidase positive glucose and sucrose fermenter.

References

  1. Parte, A.C. "Nocardia". LPSN .
  2. Wallace RJ Jr.; Tsukamura, M; Brown, BA; Brown, J; Steingrube, VA; Zhang, YS; Nash, DR (December 1990). "Cefotaxime-resistant Nocardia asteroides strains are isolates of the controversial species Nocardia farcinica". Journal of Clinical Microbiology. 28 (12): 2726–32. doi:10.1128/JCM.28.12.2726-2732.1990. PMC   268263 . PMID   2280003.
  3. Holm, P (July 1975). "Seven cases of human nocardiosis caused by Nocardia farcinica". Sabouraudia. 13 (2): 161–9. doi:10.1080/00362177585190301. PMID   1162538.
  4. Torres, O. H.; Domingo, P.; Pericas, R.; Boiron, P.; Montiel, J. A.; Vázquez, G. (3 April 2000). "Infection Caused by Nocardia farcinica : Case Report and Review". European Journal of Clinical Microbiology & Infectious Diseases. 19 (3): 205–212. doi:10.1007/s100960050460. PMID   10795594. S2CID   6487051.
  5. Malincarne, Lisa; Marroni, Massimo; Farina, Claudio; Camanni, Guido; Valente, Marina; Belfiori, Barbara; Fiorucci, Stefano; Floridi, Piero; Cardaccia, Angela; Stagni, Giuliano (1 May 2002). "Primary brain abscess with Nocardia farcinica in an immunocompetent patient". Clinical Neurology and Neurosurgery. 104 (2): 132–135. doi:10.1016/S0303-8467(01)00201-3. PMID   11932043. S2CID   35619104.
  6. Ishikawa, J; Yamashita, A; Mikami, Y; Hoshino, Y; Kurita, H; Hotta, K; Shiba, T; Hattori, M (Oct 12, 2004). "The complete genomic sequence of Nocardia farcinica IFM 10152". Proceedings of the National Academy of Sciences of the United States of America. 101 (41): 14925–30. doi: 10.1073/pnas.0406410101 . PMC   522048 . PMID   15466710.

Further reading