Onchocerca lupi | |
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Scientific classification | |
Domain: | Eukaryota |
Kingdom: | Animalia |
Phylum: | Nematoda |
Class: | Chromadorea |
Order: | Rhabditida |
Family: | Onchocercidae |
Genus: | Onchocerca |
Species: | O. lupi |
Binomial name | |
Onchocerca lupi Rodonaja, 1967 | |
Onchocerca lupi is a nematode that causes ocular onchocerciasis, an eye disease, in canines and felines. The parasite was first described in 1967 in a wolf from Georgia. [1] The other Onchocerca spp., O. volvulus , is a human parasite that causes ocular onchocerciasis in human and affects 37 million people globally. [2]
The male O. lupi worms are smaller in size than the females. Males are 43–50 mm in length and 120-200 μm in diameter. Females are 275-420 μm in diameter but the total length are unknown while the longest fragments recorded were 160–165 mm. They both are fragile and slender. [3]
Life cycle
The complete life cycle of O. lupi is still unknown. The black fly, Simulium tribulatum, is reported as a putative vector. [4]
Human Cases
The number of reported human zoonotic O. lupi infections is increasing. The first human case was reported in Turkey. The worm was removed from the subconjunctival region of the left eye of an 18-year-old girl who was experiencing pain and had the history of a fly-bite on her left upper eyelid. The morphology and molecular analysis of its partial cox1 and 12S ribosomal DNA sequences were studied to identify. [5] The additional cases have been documented in Turkey, Tunisia, Iran and the USA. [2] [6] [7] [8]
In the first reported case from USA, the infection site was unusual from all the previous cases and was found in a cervical spine of a 22-month-old girl. The magnetic resonance imaging (MRI) scan revealed that a soft tissue mass was running from C2 through C4. The left unilateral laminectomy was performed and a small biopsy of the mass was taken. The biopsy showed a mature female worm was present. It was suspected that the biopsy process might have killed the worm because the mass reduced in size. The 7 weeks follow-up revealed that the patient got better. [8]
Loa loa filariasis, (Loiasis) is a skin and eye disease caused by the nematode worm Loa loa. Humans contract this disease through the bite of a deer fly or mango fly, the vectors for Loa loa. The adult Loa loa filarial worm can reach from three to seven centimetres long and migrates throughout the subcutaneous tissues of humans, occasionally crossing into subconjunctival tissues of the eye where it can be easily observed. Loa loa does not normally affect vision but can be painful when moving about the eyeball or across the bridge of the nose. Loiasis can cause red itchy swellings below the skin called "Calabar swellings". The disease is treated with the drug diethylcarbamazine (DEC), and when appropriate, surgical methods may be employed to remove adult worms from the conjunctiva. Loiasis belongs to the group of neglected tropical diseases, and there is a call for it to be included in the high priority listing.
Loa loa is a filarial (arthropod-borne) nematode (roundworm) that causes Loa loa filariasis. Loa loa actually means "worm worm", but is commonly known as the "eye worm", as it localizes to the conjunctiva of the eye. Loa loa is commonly found in Africa. It mainly inhabits rain forests in West Africa and has native origins in Ethiopia. The disease caused by Loa loa is called loiasis and is one of the neglected tropical diseases.
Onchocerciasis, also known as river blindness, is a disease caused by infection with the parasitic worm Onchocerca volvulus. Symptoms include severe itching, bumps under the skin, and blindness. It is the second-most common cause of blindness due to infection, after trachoma.
Filariasis, is a filarial infection caused by parasitic nematodes (roundworms) spread by different vectors. They are included in the list of neglected tropical diseases.
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Lymphatic filariasis is a human disease caused by parasitic worms known as filarial worms. Usually acquired in childhood, it is a leading cause of permanent disability worldwide, impacting over a hundred million people and manifesting itself in a variety of severe clinical pathologies While most cases have no symptoms, some people develop a syndrome called elephantiasis, which is marked by severe swelling in the arms, legs, breasts, or genitals. The skin may become thicker as well, and the condition may become painful. Affected people are often unable to work and are often shunned or rejected by others because of their disfigurement and disability.
In population ecology, density-dependent processes occur when population growth rates are regulated by the density of a population. This article will focus on density dependence in the context of macroparasite life cycles.
Mansonella perstans is a filarial (arthropod-borne) nematode (roundworm), transmitted by tiny blood-sucking flies called midges. Mansonella perstans is one of two filarial nematodes that causes serous cavity filariasis in humans. The other filarial nematode is Mansonella ozzardi. M. perstans is widespread in many parts of sub-Saharan Africa, parts of Central and South America, and the Caribbean.
Mansonelliasis is the condition of infection by the nematode Mansonella. The disease exists in Africa and tropical Americas, spread by biting midges or blackflies. It is usually asymptomatic.
Onchocerca is a genus of parasitic roundworm. It contains one human parasite – Onchocerca volvulus – which is responsible for the neglected disease Onchocerciasis, also known as "river blindness" because the infected humans tend to live near rivers where host black flies live. Over 40 million people are infected in Africa, Central America, and South America. Other species affect cattle, horses, etc.
The Onchocercidae are a family of nematodes in the superfamily Filarioidea. This family includes some of the most devastating human parasitic diseases, such as lymphatic filariasis, onchocerciasis, loiasis, and other filariases.
Thelazia is a genus of nematode worms which parasitize the eyes and associated tissues of various bird and mammal hosts, including humans. They are often called "eyeworms", and infestation with Thelazia species is referred to as "thelaziasis". Adults are usually found in the eyelids, tear glands, tear ducts, or the so-called "third eyelid". Occasionally, they are found in the eyeball itself, either under the conjunctiva or in the vitreous cavity of the eyeball. All species of Thelazia for which the life cycle has been studied are transmitted by species of Diptera (flies) which do not bite, but which feed on tears.
Thelazia callipaeda is a parasitic nematode, and the most common cause of thelaziasis in humans, dogs and cats. It was first discovered in the eyes of a dog in China in 1910. By 2000, over 250 human cases had been reported in the medical literature.
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