Optic cup (embryology)

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Optic cup (embryology)
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Transverse section of head of chick embryo of forty-eight hours’ incubation. (Margin of optic cup labeled at upper right.)
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Optic cup and choroidal fissure seen from below, from a human embryo of about four weeks. (Edge of optic cup labeled at upper right.)
Details
Carnegie stage 13
Days36
Precursor optic vesicles
Identifiers
Latin cupula optica; caliculus ophthalmicus
TE E5.14.3.4.2.2.7
Anatomical terminology

During embryonic development of the eye, the outer wall of the bulb of the optic vesicles becomes thickened and invaginated, and the bulb is thus converted into a cup, the optic cup (or ophthalmic cup), consisting of two strata of cells. These two strata are continuous with each other at the cup margin, which ultimately overlaps the front of the lens and reaches as far forward as the future aperture of the pupil.

The optic cup is part of the diencephalon and gives rise to the retina of the eye.

Related Research Articles

Cranial nerves Nerves that emerge directly from the brain and the brainstem

Cranial nerves are the nerves that emerge directly from the brain, of which there are conventionally considered twelve pairs. Cranial nerves relay information between the brain and parts of the body, primarily to and from regions of the head and neck, including the special senses of vision, taste, smell, and hearing.

Optic chiasm Part of the brain where the optic nerves cross

The optic chiasm, or optic chiasma, is the part of the brain where the optic nerves cross. It is located at the bottom of the brain immediately inferior to the hypothalamus. The optic chiasm is found in all vertebrates, although in cyclostomes, it is located within the brain.

Optic nerve paired nerve that transmits visual information from the retina to the brain

The optic nerve, also known as cranial nerve II, or simply as CN II, is a paired cranial nerve that transmits visual information from the retina to the brain. In humans, the optic nerve is derived from optic stalks during the seventh week of development and is composed of retinal ganglion cell axons and glial cells; it extends from the optic disc to the optic chiasma and continues as the optic tract to the lateral geniculate nucleus, pretectal nuclei, and superior colliculus.

Olfactory nerve

The olfactory nerve is typically considered the first cranial nerve, or simply CN I, that contains sensory nerve fibers relating to the sense of smell.

Oculomotor nerve brain nerve

The oculomotor nerve is the third cranial nerve. It enters the orbit via the superior orbital fissure and innervates extrinsic eye muscles that enable most movements of the eye and that raise the eyelid. The nerve also contains fibers that innervate the intrinsic eye muscles that enable pupillary constriction and accommodation. The oculomotor nerve is derived from the basal plate of the embryonic midbrain. Cranial nerves IV and VI also participate in control of eye movement.

Orbit (anatomy) cavity or socket of the skull in which the eye and its appendages are situated

In anatomy, the orbit is the cavity or socket of the skull in which the eye and its appendages are situated. Anatomical term created by Gerard of Cremona. "Orbit" can refer to the bony socket, or it can also be used to imply the contents. In the adult human, the volume of the orbit is 30 millilitres, of which the eye occupies 6.5 ml. The orbital contents comprise the eye, the orbital and retrobulbar fascia, extraocular muscles, cranial nerves II, III, IV, V, and VI, blood vessels, fat, the lacrimal gland with its sac and nasolacrimal duct, the eyelids, medial and lateral palpebral ligaments, check ligaments, the suspensory ligament, septum, ciliary ganglion and short ciliary nerves.

Superior oblique muscle part of the eye

The superior oblique muscle, or obliquus oculi superior, is a fusiform muscle originating in the upper, medial side of the orbit which abducts, depresses and internally rotates the eye. It is the only extraocular muscle innervated by the trochlear nerve.

Diencephalon consists of structures lateral to the third ventricle, including the thalamus, hypothalamus, epithalamus, and subthalamus.

The diencephalon is a division of the forebrain, and is situated between the telencephalon and the midbrain. It consists of structures that are on either side of the third ventricle, including the thalamus, the hypothalamus, the epithalamus and the subthalamus.

Optic tract

The optic tract is a part of the visual system in the brain. It is a continuation of the optic nerve that relays information from the optic chiasm to the ipsilateral lateral geniculate nucleus (LGN), pretectal nuclei, and superior colliculus.

Longitudinal fissure Deep Groove that separates the two-halves of the Brain

The longitudinal fissure is the deep groove that separates the two cerebral hemispheres of the vertebrate brain. Lying within it is a continuation of the dura mater called the falx cerebri. The inner surfaces of the two hemispheres are convoluted by gyri and sulci just as is the outer surface of the brain.

Optic disc part of the eye

The optic disc or optic nerve head is the point of exit for ganglion cell axons leaving the eye. Because there are no rods or cones overlying the optic disc, it corresponds to a small blind spot in each eye.

Central retinal artery artery located in the retina

The central retinal artery branches off the ophthalmic artery, running inferior to the optic nerve within its dural sheath to the eyeball.

Optic canal

The optic foramen is the opening to the optic canal. The canal is located in the sphenoid bone; it is bounded medially by the body of the sphenoid and laterally by the lesser wing of the sphenoid.

Short ciliary nerves

The branches of the ciliary ganglion are the short ciliary nerves.

Ciliary arteries

The ciliary arteries are divisible into three groups, the long posterior, short posterior, and the anterior.

Optic stalk Embryonic precursor to the optic nerve

The optic vesicles project toward the sides of the head, and the peripheral part of each expands to form a hollow bulb, while the proximal part remains narrow and constitutes the optic stalk.

Optic vesicle Sac that protrudes from the embryonic forebrain to form each eye

The eyes begin to develop as a pair of diverticula (pouches) from the lateral aspects of the forebrain. These diverticula make their appearance before the closure of the anterior end of the neural tube; after the closure of the tube around the 4th week of development, they are known as the optic vesicles. Previous studies of optic vesicles suggest that the surrounding extraocular tissues – the surface ectoderm and extraocular mesenchyme – are necessary for normal eye growth and differentiation.

Olfactory tract

The olfactory tract is a bilateral bundle of afferent nerve fibers from the mitral and tufted cells of the olfactory bulb that connects to several target regions in the brain, including the piriform cortex, amygdala, and entorhinal cortex. It is a narrow white band, triangular on coronal section, the apex being directed upward.

Short posterior ciliary arteries

The short posterior ciliary arteries from six to twelve in number, arise from the ophthalmic artery as it crosses the optic nerve.

Central retinal vein

The central retinal vein is a short vein that runs through the optic nerve, leaves the optic nerve 10 mm from the eyeball and drains blood from the capillaries of the retina into either superior ophthalmic vein or into the cavernous sinus directly. The anatomy of the veins of the orbit of the eye varies between individuals, and in some the central retinal vein drains into the superior ophthalmic vein, and in some it drains directly into the cavernous sinus.

References

This article incorporates text in the public domain from page 1001 of the 20th edition of Gray's Anatomy (1918)