Pamabrom

Last updated
Pamabrom
Pamabrom.svg
Clinical data
AHFS/Drugs.com Multum Consumer Information
MedlinePlus a681004
ATC code
  • none
Legal status
Legal status
Identifiers
  • 1:1 mixture of 2-amino-2-methyl-1-propanol and 8-bromotheophyllinate
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard 100.009.186 OOjs UI icon edit-ltr-progressive.svg
Chemical and physical data
Formula 8-Bromotheophylline: C7H7BrN4O2
2-Amino-2-methyl-1-propanol: C4H11NO
Molar mass 348.20g/mol
3D model (JSmol)
  • Cn2c(=O)c1[nH]c(Br)nc1n(C)c2=O.NC(C)(C)CO
  • InChI=1S/C7H7BrN4O2.C4H11NO/c1-11-4-3(9-6(8)10-4)5(13)12(2)7(11)14;1-4(2,5)3-6/h1-2H3,(H,9,10);6H,3,5H2,1-2H3 Yes check.svgY
  • Key:ATOTUUBRFJHZQG-UHFFFAOYSA-N Yes check.svgY
 X mark.svgNYes check.svgY  (what is this?)    (verify)

Pamabrom is a product included in retail drugs available in over-the-counter medications. The active diuretic ingredient in pamabrom is 8-bromotheophylline and it also contains aminoisobutanol.

Pamabrom is available in combination with acetaminophen (paracetamol) for various conditions such as back pain and menstrual relief. [1] The acetaminophen helps reduce menstrual pains and the pamabrom reduces associated bloating. The combination is available in a number of products from various brands under different names (Midol Teen, others). The dosages are essentially the same for each brand, including generic drug store varieties.

A diuretic is also used to reduce edema (fluid buildup) in the body. Edema can cause swelling of the extremities, such as in the hands and feet. Edema can make it harder for the heart to work properly, and it can be related to congestive heart failure.

References

  1. Di Girolamo G, Sánchez AJ, De Los Santos AR, González CD (March 2004). "Is acetaminophen, and its combination with pamabrom, an effective therapeutic option in primary dysmenorrhoea?". Expert Opinion on Pharmacotherapy. 5 (3): 561–70. doi:10.1517/14656566.5.3.561. PMID   15013925. S2CID   26876035.