 | |
| Company type | Public |
|---|---|
| Industry | Pharmaceutical |
| Founded | 1984 |
| Headquarters | New Delhi, India |
Key people |
|
| Products | Pharmaceuticals, generic drugs, vaccine |
| Website | www.panaceabiotec.com |
Panacea Biotec is a global generic and specialty pharmaceutical and vaccine maker. It has principal offices in New Delhi, Mumbai, and Lalru (near Chandigarh). It has business interests in research, development, manufacturing and marketing of pharmaceutical formulations, vaccines, biosimilars, and natural products. [1]
Panacea Drugs was set up in the year 1984 and got listed in 1995 as Panacea Biotec Ltd. The company has grown organically to become one of the largest vaccine manufacturers in India.[ citation needed ]
In August 2011, several of its hepatitis vaccines were removed from the list of prequalified vaccines by the World Health Organization [2] because of quality management issues, but the issues were resolved by early 2012. [3] Its leading product, EasyFive-TT, regained WHO PQ in September 2013. [4]
As of July 2020, the company is also developing a vaccine for SARS-COV-2 using a Whole inactivated Virus approach. It got an investment in April 2020 from a US based pharma firm. [5]
In May 2021, Panacea Biotec tied up with Russian Direct Investment Fund (RDIF, Russia’s sovereign wealth fund) to produce 100 million doses of Sputnik V COVID-19 vaccine annually in India. [6] [7]
Panacea Biotec is one of the largest vaccine manufacturers and pharmaceutical companies in India. Panacea Biotec is focused on research in Vaccines, Pharmaceuticals, Biosimilars, and Nutraceuticals. It is one of the three largest biotechnology companies in India. [8] The company develops and produces medicines for a wide range of medical disciplines, including oncology, organ transplant, immunology and pain management, gastroenterology, vaccines, and diabetology/endocrinology.[ citation needed ]
Panacea Biotec has many drugs for kidney and liver transplant such as Tacrolimus (marketed as PanGraf), Mycophenolic acid (Mycept), mycophenolate sodium (Mycept S), etc. It also markets generic forms of Tacrolimus [9] in the United States, [10] Germany, among many other developing countries.
Panacea Biotec has a focused presence in nephrology therapy in the highly specialized organ transplantation and dialysis management segments. It offers a range of pre-transplant and post-transplant therapies that include drugs such as lanthanum carbonate, sevelamer, and valganciclovir in conventional and novel drug delivery systems.[ citation needed ]
Panacea Biotec has many products for treatment of arthritis, haemorrhoids, acid reflux, and other gastrointestinal problems. Its most prominent product is Sitcom, a euphorbia prostata extract that helps different grades of haemorrhoids. It also markets a once-a-day combination of regular and controlled-release Aceclofenac (generic to Clanza CR) under the brand name Willgo CR.
Panacea Biotec has many brands marketed in India for the 'affordable' treatment for cancer, viz, breast cancer, brain tumor, ovarian cancer, pancreatic cancer, prostate cancer and colorectal cancer. One of its most prominent brand in this segment is, PacliAll, which is a generic version of Abraxane Protein-bound paclitaxel. The company has plans to market the product in the US as per the patent settlement. [11]
The company has extensively focused on its diabetic portfolio with formulations such as gliclazide, metformin, and glimepiride that are marketed in India and other developing markets under the brand names Glizid, Glizid M, Glizid MR, Betaglim, and Metlong. It is one of the largest diabetic companies in its represented market.
Panacea Biotec markets many generic and novel vaccines in India and many global markets. Some of its vaccines are Pre-qualified by the WHO.
The listing below is for named vaccines; Panacea Biotec produces many vaccines which do not bear trade names.
Panacea Biotec sold its near-completed hospital in Delhi NCR to Narayana Hrudayalaya in April 2017 [12] for 180 crores; effectively, exiting the hospital business.
Sanofi S.A. is a French multinational pharmaceutical and healthcare company headquartered in Paris, France. The corporation was established in 1973 and merged with Synthélabo in 1999 to form Sanofi-Synthélabo. In 2004, Sanofi-Synthélabo merged with Aventis and renamed to Sanofi-Aventis, which were each the product of several previous mergers. It changed its name back to Sanofi in May 2011. The company is a component of the Euro Stoxx 50 stock market index. In 2023, the company’s seat in Forbes Global 2000 was 89.
The DPT vaccine or DTP vaccine is a class of combination vaccines against three infectious diseases in humans: diphtheria, pertussis, and tetanus (lockjaw). The vaccine components include diphtheria and tetanus toxoids, and either killed whole cells of the bacterium that causes pertussis or pertussis antigens. The term toxoid refers to vaccines which use an inactivated toxin produced by the pathogen which they are targeted against to generate an immune response. In this way, the toxoid vaccine generates an immune response which is targeted against the toxin which is produced by the pathogen and causes disease, rather than a vaccine which is targeted against the pathogen itself. The whole cells or antigens will be depicted as either "DTwP" or "DTaP", where the lower-case "w" indicates whole-cell inactivated pertussis and the lower-case "a" stands for "acellular". In comparison to alternative vaccine types, such as live attenuated vaccines, the DTP vaccine does not contain any live pathogen, but rather uses inactivated toxoid to generate an immune response; therefore, there is not a risk of use in populations that are immune compromised since there is not any known risk of causing the disease itself. As a result, the DTP vaccine is considered a safe vaccine to use in anyone and it generates a much more targeted immune response specific for the pathogen of interest.
Parke-Davis is a subsidiary of the pharmaceutical company Pfizer. Although Parke, Davis & Co. is no longer an independent corporation, it was once America's oldest and largest drug maker, and played an important role in medical history. In 1970 Parke-Davis was acquired by Warner–Lambert, which in turn was acquired by Pfizer in 2000.
Biocon Limited is an Indian biopharmaceutical company based in Bangalore. It was founded by Kiran Mazumdar-Shaw in 1978. The company manufactures generic active pharmaceutical ingredients (APIs) that are sold in approximately 120 countries, including the United States and Europe. It also manufactures novel biologics as well as biosimilar insulins and antibodies, which are sold in India as branded formulations. Biocon's biosimilar products are also sold in both bulk and formulation forms in several emerging markets.
A biopharmaceutical, also known as a biological medical product, or biologic, is any pharmaceutical drug product manufactured in, extracted from, or semisynthesized from biological sources. Different from totally synthesized pharmaceuticals, they include vaccines, whole blood, blood components, allergenics, somatic cells, gene therapies, tissues, recombinant therapeutic protein, and living medicines used in cell therapy. Biologics can be composed of sugars, proteins, nucleic acids, or complex combinations of these substances, or may be living cells or tissues. They are isolated from living sources—human, animal, plant, fungal, or microbial. They can be used in both human and animal medicine.
Hetero Drugs is an Indian pharmaceutical company and the world's largest producer of anti-retroviral drugs. Hetero's business includes APIs, generics, biosimilars, custom pharmaceutical services, and branded generics.
Sanofi Pasteur is the vaccines division of the French multinational pharmaceutical company Sanofi. Sanofi Pasteur is the largest company in the world devoted entirely to vaccines. It is one of four global producers of the yellow fever vaccine.
Zydus Lifesciences Limited, formerly known as Cadila Healthcare Limited, is an Indian multinational pharmaceutical company headquartered in Ahmedabad, which is primarily engaged in the manufacturing of generic drugs. The company ranked 100th in the Fortune India 500 list in 2020.
Serum Institute of India (SII) is an Indian biotechnology and biopharmaceuticals company, based in Pune. It was founded by Cyrus Poonawalla in 1966 and is a part of Cyrus Poonawalla Group.
The Haemophilus influenzae type B vaccine, also known as Hib vaccine, is a vaccine used to prevent Haemophilus influenzae type b (Hib) infection. In countries that include it as a routine vaccine, rates of severe Hib infections have decreased more than 90%. It has therefore resulted in a decrease in the rate of meningitis, pneumonia, and epiglottitis.
Pertussis vaccine is a vaccine that protects against whooping cough (pertussis). There are two main types: whole-cell vaccines and acellular vaccines. The whole-cell vaccine is about 78% effective while the acellular vaccine is 71–85% effective. The effectiveness of the vaccines appears to decrease by between 2 and 10% per year after vaccination with a more rapid decrease with the acellular vaccines. The vaccine is only available in combination with tetanus and diphtheria vaccines. Pertussis vaccine is estimated to have saved over 500,000 lives in 2002.
Biological E Limited is an Indian biotechnology and biopharmaceutical company based in Hyderabad, Telangana. It specialises in the areas of low-cost vaccine production.
DTwP-HepB-Hib vaccine is a 5-in-1 combination vaccine with five individual vaccines conjugated into one. It protects against diphtheria, tetanus, whooping cough, hepatitis B and Haemophilus influenzae type B, which is generally used in middle- and low-income countries, where polio vaccine is given separately.
DTaP-IPV vaccine is a combination vaccine whose full generic name is diphtheria and tetanus toxoids and acellular pertussis adsorbed and inactivated poliovirus vaccine (IPV).
DTaP-IPV/Hib vaccine is a 5-in-1 combination vaccine that protects against diphtheria, tetanus, whooping cough, polio, and Haemophilus influenzae type B.
DTaP-IPV-HepB vaccine is a combination vaccine whose generic name is diphtheria and tetanus toxoids and acellular pertussis adsorbed, hepatitis B (recombinant) and inactivated polio vaccine or DTaP-IPV-Hep B. It protects against the infectious diseases diphtheria, tetanus, pertussis, poliomyelitis, and hepatitis B.
DPT-Hib vaccine is a combination vaccine whose generic name is diphtheria and tetanus toxoids and whole-cell pertussis vaccine adsorbed with Hib conjugate vaccine, sometimes abbreviated to DPT-Hib. It protects against the infectious diseases diphtheria, tetanus, pertussis, and Haemophilus influenzae type B.
DTaP-Hib vaccine is a combination vaccine whose generic name is diphtheria and tetanus toxoids and acellular pertussis adsorbed with Haemophilus B conjugate vaccine, sometimes abbreviated to DTaP-Hib. It protects against the infectious diseases diphtheria, tetanus, pertussis, and Haemophilus influenzae type B.
A hexavalent vaccine, or 6-in-1 vaccine, is a combination vaccine with six individual vaccines conjugated into one, intended to protect people from multiple diseases. The term usually refers to the children's vaccine that protects against diphtheria, tetanus, pertussis, poliomyelitis, haemophilus B, and hepatitis B, which is used in more than 90 countries around the world including in Europe, Canada, Australia, Jordan, and New Zealand.
