Pentanoyl chloride

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Pentanoyl chloride
Pentanoyl chloride.svg
Names
Preferred IUPAC name
Pentanoyl chloride
Other names
Valeroyl chloride; n-Pentanoyl chloride
Identifiers
3D model (JSmol)
ECHA InfoCard 100.010.301 OOjs UI icon edit-ltr-progressive.svg
PubChem CID
UNII
  • CCCCC(=O)Cl
Properties
C5H9ClO
Molar mass 120.58 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Pentanoyl chloride is an acyl chloride derived from pentanoic acid. It is a colorless liquid that is used to attach the valeroyl group. It is usually produced by chlorination of valeric acid. [1]

Reactions

Like related acyl chlorides, valeryl chloride hydrolyzes readily:

CH3(CH2)3C(O)Cl + H2O → CH3(CH2)3CO2H + HCl

Alcohols react to give esters:

CH3(CH2)3C(O)Cl + ROH → CH3(CH2)3CO2R + HCl

Amines react to give amides:

CH3(CH2)3C(O)Cl + R2NH → CH3(CH2)3C(O)NR2 + HCl

Benzene reacts under conditions of the Friedel-Crafts reaction to give valerophenone:

CH3(CH2)3C(O)Cl + C6H6 → CH3(CH2)3C(O)C6H5 + HCl

Related Research Articles

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In organic chemistry, an acyl chloride (or acid chloride) is an organic compound with the functional group -COCl. Their formula is usually written RCOCl, where R is a side chain. They are reactive derivatives of carboxylic acids. A specific example of an acyl chloride is acetyl chloride, CH3COCl. Acyl chlorides are the most important subset of acyl halides.

Acyl halide Chemical compound

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Copper(I) chloride Chemical compound

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Chromium(III) chloride Chemical compound

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Acetyl chloride Chemical compound

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Oxalyl chloride Chemical compound

Oxalyl chloride is a chemical compound with the formula (COCl)2. This colorless, sharp-smelling liquid, the diacyl chloride of oxalic acid, is a useful reagent in organic synthesis.

Thionyl chloride Chemical compound

Thionyl chloride is an inorganic compound with the chemical formula SOCl
2
. It is a moderately volatile colourless liquid with an unpleasant acrid odour. Thionyl chloride is primarily used as a chlorinating reagent, with approximately 45,000 tonnes per year being produced during the early 1990s, but is occasionally also used as a solvent. It is toxic, reacts with water, and is also listed under the Chemical Weapons Convention as it may be used for the production of chemical weapons.

Benzoyl chloride Chemical compound

Benzoyl chloride, also known as benzenecarbonyl chloride, is an organochlorine compound with the formula C7H5ClO. It is a colourless, fuming liquid with an irritating odour. It is mainly useful for the production of peroxides but is generally useful in other areas such as in the preparation of dyes, perfumes, pharmaceuticals, and resins.

Phosphorus pentachloride Chemical compound

Phosphorus pentachloride is the chemical compound with the formula PCl5. It is one of the most important phosphorus chlorides, others being PCl3 and POCl3. PCl5 finds use as a chlorinating reagent. It is a colourless, water-sensitive and moisture-sensitive solid, although commercial samples can be yellowish and contaminated with hydrogen chloride.

Phosphorus trichloride Chemical compound

Phosphorus trichloride is a inorganic compound with the chemical formula PCl3. A colorless liquid when pure, it is an important industrial chemical, being used for the manufacture of phosphites and other organophosphorus compounds. It is toxic and reacts readily with water to release hydrogen chloride.

Rhodium(III) chloride Chemical compound

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Triflic acid Chemical compound

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Chlorosulfuric acid Chemical compound

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Nitrosyl chloride Chemical compound

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Thiophosphoryl chloride Chemical compound

Thiophosphoryl chloride is an inorganic compound with the formula PSCl3. It is a colorless pungent smelling liquid that fumes in air. It is synthesized from phosphorus chloride and used to thiophosphorylate organic compounds, such as to produce insecticides.

4-Toluenesulfonyl chloride Chemical compound

4-Toluenesulfonyl chloride (p-toluenesulfonyl chloride, toluene-p-sulfonyl chloride) is an organic compound with the formula CH3C6H4SO2Cl. This white, malodorous solid is a reagent widely used in organic synthesis. Abbreviated TsCl or TosCl, it is a derivative of toluene and contains a sulfonyl chloride (−SO2Cl) functional group.

Butyryl chloride Chemical compound

Butyryl chloride is an organic compound with the chemical formula CH3CH2CH2C(O)Cl. It is a colorless liquid with a pungent odor. Butyryl chloride is soluble in aprotic organic solvents, but it reacts readily with water and alcohols. It is usually produced by chlorination of butyric acid.

Transition metal acyl complexes

Transition metal acyl complexes describes organometallic complexes containing one or more acyl (RCO) ligands. Such compounds occur as transient intermediates in many industrially useful reactions, especially carbonylations.

References

  1. Helferich, B.; Schaefer, W. (1929). "n-Butyryl Chloride". Org. Synth. 9: 32. doi:10.15227/orgsyn.009.0032.