Rho associated coiled-coil containing protein kinase 2 is a protein that in humans is encoded by the ROCK2 gene. [5] Fasudil is an inhibitor of ROCK protein.
Rho associated coiled-coil containing protein kinase 2 is a protein that in humans is encoded by the ROCK2 gene. [5] Fasudil is an inhibitor of ROCK protein.
The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.
ROCK1 is a protein serine/threonine kinase also known as rho-associated, coiled-coil-containing protein kinase 1. Other common names are ROKβ and P160ROCK. ROCK1 is a major downstream effecter of the small GTPase RhoA and is a regulator of the actomyosin cytoskeleton which promotes contractile force generation. ROCK1 plays a role in cancer and in particular cell motility, metastasis, and angiogenesis.
Protein kinase C beta type is an enzyme that in humans is encoded by the PRKCB gene.
Alpha-catulin is a protein that in humans is encoded by the CTNNAL1 gene.
Fasciculation and elongation protein zeta-2 is a protein that in humans is encoded by the FEZ2 gene.
Protein phosphatase 1F is an enzyme that in humans is encoded by the PPM1F gene.
Diacylglycerol kinase theta is an enzyme that in humans is encoded by the DGKQ gene.
Coiled coil domain containing 90B, also known as CCDC90B, is a protein encoded by the CCDC90B gene.
Pleckstrin homology domain containing, family G member 5 (PLEKHG5) is a protein that in humans is encoded by the PLEKHG5 gene. Eight transcript variants encoding different isoforms have been found for this gene.
A kinase (PRKA) interacting protein 1 is a protein in humans that is encoded by the AKIP1 gene.
Calcium/calmodulin-dependent protein kinase ID is a protein in humans that is encoded by the CAMK1D gene on chromosome 10.
EF-hand and coiled-coil domain containing 1 is a protein that in humans is encoded by the EFCC1 gene.
Transport and Golgi organization protein 6 homolog also known as transmembrane and coiled-coil domain-containing protein 7 is a protein that in humans is encoded by the TANGO6 gene.
Tripartite motif containing 69 is a protein that in humans is encoded by the TRIM69 gene.
Coiled-coil domain containing 17 is a protein that in humans is encoded by the CCDC17 gene.
Thymidine kinase 2, mitochondrial is a protein that in humans is encoded by the TK2 gene.
Coiled-coil domain containing 18 is a protein that in humans is encoded by the CCDC18 gene.
Janus kinase and microtubule interacting protein 2 is a protein that in humans is encoded by the JAKMIP2 gene.
Dual specificity phosphatase 8 is a protein that in humans is encoded by the DUSP8 gene.
Coiled-coil domain-containing protein 181 (CCDC181) is a protein that in human is encoded by C1orf114, which is located at the Chromosome 1 at 1q24.2. The accession is Q5T1D7. Researches have recently revealed that CCDC 181 is a microtubule-binding protein that interacts with murine Hook1 in haploid male germ cells and localizes to the sperm tail and motile cilia. The disruption of Hook1 may lead to inappropriate function of spermatogenesis. The dysfunction may be related to the abnormal head shape of sperm or distinctive structural changes in flagella in sperm, which can result in male infertility. An increased rate of my gene has found in the haploid phase of male cell during meiosis, thus it is believed to relate to sperm cell and aid in spermatogenesis.
CDC42 effector protein 5 is a protein that in humans is encoded by the CDC42EP5 gene.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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