Robert Jarvik

Last updated
Robert Jarvik
Born
Robert Koffler Jarvik

(1946-05-11) May 11, 1946 (age 77)
Alma mater Syracuse University
New York University
Occupation(s) Scientist, researcher
Known forDeveloping the Jarvik-7 artificial heart
Spouses
Elaine Levin
(m. 1968;div. 1985)
(m. 1987)
Children2
Relatives Murray Jarvik (paternal uncle)
Website

Robert Koffler Jarvik (born May 11, 1946) is an American scientist, researcher, and entrepreneur known for his role in developing the Jarvik-7 artificial heart.

Contents

Early life

Robert Jarvik was born in Midland, Michigan, to Norman Eugene Jarvik and Edythe Koffler Jarvik, and raised in Stamford, Connecticut. [1] He is the brother to Jonathan Jarvik, a biological sciences professor at Carnegie Mellon University, [2] as well as the nephew of Murray Jarvik, a pharmacologist who was the co-inventor of the nicotine patch. [3] [4] At an early age, Jarvik showed interest in mechanics and medicine, which would later influence his works. [5] He already obtained five patents for his inventions at the age of 17. [6]

Jarvik is a graduate of Syracuse University. [5] He earned a master's degree in medical engineering from New York University. [7]

After being admitted to the University of Utah School of Medicine, Jarvik completed two years of study, and in 1971 was hired by Willem Johan Kolff, a Dutch-born physician-inventor at the University of Utah, [7] who produced the first dialysis machine, and who was working on other artificial organs, including a heart. Jarvik received his M.D. in 1976 from the University of Utah. Jarvik is a medical scientist, and did not complete an internship or residency and has never been licensed to practice medicine. [8] [9]

Career

Jarvik joined the University of Utah's artificial organs program in 1971, then headed by Willem Johan Kolff, his mentor. At the time, the program used a pneumatic artificial heart design by Clifford Kwan-Gett that had sustained an animal in the lab for 10 days. Kolff assigned Jarvik to design a new heart that would overcome the problems of the Kwan-Gett heart, eventually culminating with the Jarvik-7 device. [10]

In 1982, the team carried out an artificial heart implant - the second ever, 13 years after Domingo Liotta and Denton Cooley's first in 1969. [11] William DeVries first implanted the Jarvik-7 into retired dentist Barney Clark at the University of Utah on December 1, 1982. Clark required frequent visits to the hospital for the next 112 days, after which he died. During frequent press conferences to update the patient's condition, Jarvik, along with DeVries, briefed the world's media on Clark's condition. The next several implantations of the Jarvik-7 heart were conducted by Humana, a large health care insurance company. The second patient, William J. Schroeder, survived 620 days. [12] In 1983, Jarvik and DeVries received the Golden Plate Award of the American Academy of Achievement. [13]

In 2006, Jarvik began appearing in television commercials for Pfizer's cholesterol medication Lipitor. Two members of Congress, as part of their campaign against celebrity endorsements, began an investigation as to whether his television advertisements constitute medical advice given without a license to practice medicine. One commercial depicted Jarvik rowing, he did not row himself, and a body double was used. [14] Later, Jarvik said that he had not taken Lipitor until becoming a spokesman for the company. [15] On February 25, 2008, Pfizer announced that it would discontinue its ads with Jarvik. [16]

Personal life

Jarvik has been married twice. He has a son and daughter with his first wife, Salt Lake City writer and journalist Elaine Jarvik. [17] [18] In 2011, she and her daughter wrote the play, A Man Enters, inspired by Jarvik's absent relationship with his children since their divorce. [17]

Jarvik has been married to Parade magazine columnist Marilyn vos Savant since August 23, 1987. [19]

Contrary to some sources, [20] Jarvik is not a member of the Church of Jesus Christ of Latter-day Saints. [21]

Related Research Articles

<span class="mw-page-title-main">William DeVries</span> American physician

William Castle DeVries is an American cardiothoracic surgeon, mainly known for the first transplant of a TAH using the Jarvik-7 model.

<span class="mw-page-title-main">Artificial heart</span> Mechanical device which replaces the heart

An artificial heart is a device that replaces the heart. Artificial hearts are typically used to bridge the time to heart transplantation, or to permanently replace the heart in the case that a heart transplant is impossible. Although other similar inventions preceded it from the late 1940s, the first artificial heart to be successfully implanted in a human was the Jarvik-7 in 1982, designed by a team including Willem Johan Kolff, William DeVries and Robert Jarvik.

<span class="mw-page-title-main">Denton Cooley</span> American heart and cardiothoracic surgeon (1920–2016)

Denton Arthur Cooley was an American cardiothoracic surgeon famous for performing the first implantation of a total artificial heart. Cooley was also the founder and surgeon in-chief of The Texas Heart Institute, chief of Cardiovascular Surgery at clinical partner Baylor St. Luke's Medical Center, consultant in Cardiovascular Surgery at Texas Children's Hospital and a clinical professor of Surgery at the University of Texas Health Science Center at Houston.

William J. Schroeder, was one of the first recipients of an artificial heart. Schroeder was born in Jasper, Indiana, and was a Sergeant in the United States Air Force from 1952 to 1966. On November 25, 1984, at the age of 52, became the second human recipient of the Jarvik 7. The transplant was performed at Humana Heart Institute International in Louisville, Kentucky by Dr. William C. DeVries.

Nicorette is the brand name of a number of products for nicotine replacement therapy (NRT) that contain nicotine polacrilex. Developed in the late 1970s in Sweden by AB Leo in the form of a chewing gum, Nicorette was the first nicotine replacement product on the market.

<span class="mw-page-title-main">Torcetrapib</span> Chemical compound

Torcetrapib was a drug being developed to treat hypercholesterolemia and prevent cardiovascular disease. Its development was halted in 2006 when phase III studies showed excessive all-cause mortality in the treatment group receiving a combination of atorvastatin (Lipitor) and torcetrapib.

<span class="mw-page-title-main">Ventricular assist device</span> Medical device to assist or replace a heart

A ventricular assist device (VAD) is an electromechanical device for assisting cardiac circulation, which is used either to partially or to completely replace the function of a failing heart. The function of a VAD differs from that of an artificial cardiac pacemaker in that a VAD pumps blood, whereas a pacemaker delivers electrical impulses to the heart muscle. Some VADs are for short-term use, typically for patients recovering from myocardial infarction (heart attack) and for patients recovering from cardiac surgery; some are for long-term use (months to years to perpetuity), typically for patients with advanced heart failure.

<span class="mw-page-title-main">Willem Johan Kolff</span> Dutch medical researcher (1911–2009)

Willem Johan "Pim" Kolff was a pioneer of hemodialysis, artificial heart, as well as in the entire field of artificial organs. Willem was a member of the Kolff family, an old Dutch patrician family. He made his major discoveries in the field of dialysis for kidney failure during the Second World War. He emigrated in 1950 to the United States, where he obtained US citizenship in 1955, and received a number of awards and widespread recognition for his work.

<span class="mw-page-title-main">O. H. Frazier</span> American physician

O. H. "Bud" Frazier is a heart surgeon and director of cardiovascular surgery research at the Texas Heart Institute (THI), best known for his work in mechanical circulatory support (MCS) of failing hearts using left ventricular assist devices (LVAD) and total artificial hearts (TAH).

Jarvik is a surname. Notable people with the surname include:

Murray Elias Jarvik was an American psychopharmacologist and academic who was among the first scientists to study d-lysergic acid, the precursor to LSD, and later became the co-inventor of the nicotine patch. He was a longtime professor emeritus at University of California-Los Angeles, where he taught as a professor of psychiatry and pharmacology for many years.

<span class="mw-page-title-main">University of Utah Hospital</span> Hospital in Utah, United States

The University of Utah Hospital is a research and teaching hospital on the campus of the University of Utah in Salt Lake City, Utah. It serves as a major regional referral center for Utah and the surrounding states of Idaho, Nevada, Wyoming, Montana and New Mexico. University of Utah Health Care is praised for the following specialties: cardiology, geriatrics, gynecology, pediatrics, rheumatology, pulmonology, neurology, oncology, orthopedics, and ophthalmology.

Bruce D. Roth is an American organic and medicinal chemist who trained at Iowa State University and the University of Rochester, and, at the age of 32, discovered atorvastatin, the statin-class drug sold as Lipitor that would become the largest-selling drug in pharmaceutical history. His honours include being named a 2008 Hero of Chemistry by the American Chemical Society, and being chosen as the Perkin Medal awardee, the highest honour given in the U.S. chemical industry, by the Society of Chemical Industry, American section in 2013.

Morton Maimon Mower was an American cardiologist specializing in electrophysiology and the co-inventor of the automatic implantable cardioverter defibrillator. He served in several professional capacities at Sinai Hospital and Cardiac Pacemakers Inc. In 1996, he became the chairman and chief executive officer of Mower Research Associates. He was inducted into the National Inventors Hall of Fame in 2002 for the development of the automatic implantable cardioverter defibrillator with Michel Mirowski in the 1970s. He continued his research in the biomechanical engineering laboratories at Johns Hopkins University.

The University of Utah Research Park, also known as Bionic Valley, is located on the campus of the University of Utah in Salt Lake City, United States. The facility has helped create many businesses based on the work of university scientists over the years. Research Park now houses more than forty companies alongside sixty-nine academic departments and employs more than 7,500 people. The annual in-state productivity of park residents exceeds $550 million.

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The University of Utah School of Medicine is located on the upper campus of the University of Utah in Salt Lake City, Utah. It was founded in 1905 and is currently the only MD-granting medical school in the state of Utah.

<span class="mw-page-title-main">Clifford Kwan-Gett</span>

Clifford Stanley Kwan-Gett is an Australian-born Chinese American engineer, physician, and artificial heart pioneer.

<span class="mw-page-title-main">CHI St. Luke's Health</span>

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Jack Greene Copeland is an American cardiothoracic surgeon, who has established procedures in heart transplantation including repeat heart transplantation, the implantation of total artificial hearts (TAH) to bridge the time to heart transplant, innovations in left ventricular assist devices (LVAD) and the technique of "piggybacking" a second heart in a person, while leaving them the original.

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References

Inline citations

  1. "Men in the News: A Pair of Skilled Hands to Guide an Artificial Heart: Robert Kiffler Jarvik". Article in The New York Times, 3 December 1982. Retrieved from on 2006-06-23.
  2. University, Carnegie Mellon. "Jonathan W. Jarvik - Biological Sciences - Carnegie Mellon University". www.cmu.edu. Retrieved 2022-07-16.
  3. Maugh II, Thomas (2008-05-14). "Dr. Murray E. Jarvik, 84; UCLA pharmacologist invented nicotine patch". Los Angeles Times . Retrieved 2008-05-26.
  4. "Dr. Murray Jarvik, co-inventor of nicotine patch, dies at 84 in Santa Monica". International Herald Tribune. Associated Press. 2008-05-10. Retrieved 2008-05-26.
  5. 1 2 "Jarvik, Robert Koffler | Encyclopedia.com". www.encyclopedia.com. Retrieved 2023-08-11.
  6. Baumgold, Julie (February 6, 1989). "In the Kingdom of the Brain". New York Magazine. 22 (6): 43.
  7. 1 2 "Milestones". Rime Magazine, March 2, 2009 p.18
  8. "Men in the News: A Pair of Skilled Hands to Guide an Artificial Heart: Robert Kiffler Jarvik". Article in The New York Times, 3 December 1982. Retrieved from on 2007-05-27.
  9. "Is this celebrity doctor's TV ad right for you?". Article in NBC News, 1 March 2007. Retrieved from on 2007-05-27.
  10. "Salem Press". Archived from the original on 2010-11-28. Retrieved 2010-06-14. Great Lives from History: Inventors and Inventions -- Robert Jarvik
  11. Liotta/Cooley "Orthotopic Cardiac Prosthesis for Two-Staged Cardiac Replacement," which appears in Volume 24 (1969) of the American Journal of Cardiology (pp. 723-730).
  12. Artificial Heart – Early developments
  13. "Golden Plate Awardees of the American Academy of Achievement". www.achievement.org. American Academy of Achievement.
  14. "Congress questions Jarvik's credentials in celebrity ad" The State, January 8, 2008. http://www.thestate.com/nation/story/278107.html%5B%5D
  15. American Medical Association Journal of Ethics October 2010, Volume 12, Number 10: 818-823
  16. Bazell, Robert (1 March 2007). "Is this celebrity doctor's TV ad right for you?". NBC News.
  17. 1 2 "A Man Enters". Utah Stories. 2011-11-03. Retrieved 2020-02-23.
  18. Gonzales, Laurence (1989). The Still Point . University of Arkansas Press. p.  47. ISBN   978-1-55728-081-7. Elaine Levin Jarvik.
  19. "About Marilyn". Archived from the original on 2006-05-07. Retrieved 2007-11-03.
  20. Brother Paul's Mormon Bathroom Reader
  21. Skousen, Paul B.; Moon, Harold K. (November 1, 2005), Brother Paul's Mormon Bathroon Reader, Cedar Fort, p. 39. Archived at Google Books. Retrieved March 21, 2016.

General references