Small Cajal body specific RNA 14 | |
---|---|
Identifiers | |
Symbol | SCARNA14 |
Alt. Symbols | snoU100 |
Rfam | RF00582 |
Other data | |
RNA type | Gene; snRNA; snoRNA; scaRNA |
Domain(s) | Eukaryota |
GO | GO:0006396 GO:0015030 GO:0005730 |
SO | SO:0000275 |
PDB structures | PDBe |
In molecular biology, Small Cajal body specific RNA 14 (also known as scaRNA14 or U100) is a small nucleolar RNA found in Cajal bodies.
scaRNAs are a specific class of small nucleolar RNAs which localise to the Cajal bodies and guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12. [1] [2] U100 belongs to the H/ACA box class of guide RNAs as it has the predicted hairpin-hinge-hairpin-tail structure and the conserved H/ACA-box motifs. [3]
U100 is the human orthologue of mouse H/ACA snoRNA MBII-201 which is also included in this family. [4] U100 is predicted to guide the pseudouridylation of U2 snRNA at residue U7. [5]
In molecular biology, Small nucleolar RNAs (snoRNAs) are a class of small RNA molecules that primarily guide chemical modifications of other RNAs, mainly ribosomal RNAs, transfer RNAs and small nuclear RNAs. There are two main classes of snoRNA, the C/D box snoRNAs, which are associated with methylation, and the H/ACA box snoRNAs, which are associated with pseudouridylation. SnoRNAs are commonly referred to as guide RNAs but should not be confused with the guide RNAs that direct RNA editing in trypanosomes.
In molecular biology, Small Cajal body specific RNA 11 is a small nucleolar RNA found in Cajal bodies.
In molecular biology, Small Cajal body specific RNA 13 is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation of U2 and U5 spliceosomal RNA.
Small Cajal body specific RNA 15 is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation of U1 spliceosomal RNA.
Small Cajal body specific RNA 16 is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation of U1 spliceosomal RNA.
Small Cajal body specific RNA 23 is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation of U1 spliceosomal RNA.
Small Cajal body specific RNA 24 is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation of U6 spliceosomal RNA.
Small Cajal body specific RNA 25 is a scaRNA, which are a class of ncRNAs characterised as small nuclear RNAs localised to the Cajal bodies.
In molecular biology, small Cajal body specific RNA 4 is believed to be a guide RNA of the H/ACA box class, since it has the predicted hairpin-hinge-hairpin-tail structure, conserved H/ACA-box motifs, and is found associated with GAR1. In particular, ACA26 is predicted to guide the pseudouridylation of residues U39 and U41 in U2 snRNA. Such scaRNAs are a specific class of small nuclear RNAs that localise to the Cajal bodies and guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12.
Small Cajal body specific RNA 6 is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation of U5 spliceosomal RNA.
Small Cajal body specific RNA 8 is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation of U2 spliceosomal RNA.
In molecular biology, SNORA26 is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
In molecular biology, SNORA30 is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of eukaryotic cells. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a 'guide RNA' as it 'guides' the modification process.
In molecular biology, Small nucleolar RNA SNORA44 is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a 'guide RNA'.
In molecular biology, Small nucleolar RNA SNORA57 is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a "guide RNA".
In molecular biology, Small nucleolar RNA SNORA58 is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a "guide RNA".
In molecular biology, SNORA65 is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a 'guide RNA'.
Small Cajal body-specific RNAs (scaRNAs) are a class of small nucleolar RNAs (snoRNAs) that specifically localise to the Cajal body, a nuclear organelle involved in the biogenesis of small nuclear ribonucleoproteins. ScaRNAs guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12.
In molecular biology, Small Cajal body specific RNA 20 is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation of U12 minor spliceosomal RNA.
In molecular biology, Small Cajal body specific RNA 21 is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation of U12 minor spliceosomal RNA.