Small Cajal body specific RNA 25

Last updated
Small Cajal body specific RNA 3
RF00565.jpg
Identifiers
SymbolSCARNA3
Rfam RF00565
Other data
RNA typeGene; snRNA; snoRNA; scaRNA;
PDB structures PDBe

Small Cajal body specific RNA 25 (otherwise known as scaRNA25, HBI-100, MBI-100, and MBI-114) is a scaRNA, which are a class of ncRNAs characterised as small nuclear RNAs localised to the Cajal bodies. [1]

ScaRNA25 was originally identified in a large scale cloning project in mice. [2] Later sequence analysis predicted that this RNA guides the pseudouridylation of position U40 in the U6 snRNA. [2]

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<span class="mw-page-title-main">Small Cajal body specific RNA 6</span>

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<span class="mw-page-title-main">Small Cajal body-specific RNA</span>

Small Cajal body-specific RNAs (scaRNAs) are a class of small nucleolar RNAs (snoRNAs) that specifically localise to the Cajal body, a nuclear organelle involved in the biogenesis of small nuclear ribonucleoproteins. ScaRNAs guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12.

<span class="mw-page-title-main">Small Cajal body specific RNA 20</span>

In molecular biology, Small Cajal body specific RNA 20 is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation of U12 minor spliceosomal RNA.

<span class="mw-page-title-main">Small Cajal body specific RNA 21</span>

In molecular biology, Small Cajal body specific RNA 21 is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation of U12 minor spliceosomal RNA.

References

  1. Darzacq, Xavier; Jády, Beáta E.; Verheggen, Céline; Kiss, Arnold M.; Bertrand, Edouard; Kiss, Tamás (2002). "Cajal body-specific small nuclear RNAs: A novel class of 2'-O-methylation and pseudouridylation guide RNAs". The EMBO Journal . 21 (11): 2746–2756. doi:10.1093/emboj/21.11.2746. PMC   126017 . PMID   12032087.
  2. 1 2 Huttenhofer, Alexander; Kiefmann, Martin; Meier-Ewert, Sebastian; O'Brien, John; Lehrach, Hans; Bachellerie, Jean-Pierre; Brosius, Jürgen (1 June 2001). "RNomics: an experimental approach that identifies 201 candidates for novel, small, non-messenger RNAs in mouse". The EMBO Journal . 20 (11): 2943–2953. doi:10.1093/emboj/20.11.2943. PMC   125495 . PMID   11387227.