Steven D. Wexner

Last updated
Steven D. Wexner
Steven Wexner Headshot.png
Born
United States
Education Weill Cornell Medicine (MD)
Columbia University
Occupation Surgeon
Medical career
Field Colorectal Surgery
Institutions Cleveland Clinic Florida
Website my.clevelandclinic.org/staff/202-steven-wexner

Steven D. Wexner is an American surgeon and physician. [1] He is Director of the Ellen Leifer Shulman and Steven Shulman Digestive Disease Center at Cleveland Clinic Florida. [2] [3] [4] Wexner has received numerous regional, national, and international research awards. [5] Through his multiple academic appointments, Wexner personally trains 15-20 surgeons each year, and he educates thousands more around the world through conferences and lectures. [6] He is a resource for his colleagues from around the world for referral of patients with challenging or complex problems. [7] In 2020, he was elected vice-chair of the Board of Regents of the American College of Surgeons for a one-year term. [8] Since 1990. he has served as Symposium Director of the Cleveland Clinic Annual International Colorectal Disease Symposium. The Symposium was held in Fort Lauderdale or Boca Raton every year from 1990 to 2019. Since 2020, the Symposium has expanded to include host locations outside of the US with interruptions during the pandemic years of 2021–2022. [1]

Contents

Education

Wexner received his bachelor's degree from Columbia University in 1978. He earned his MD in 1982 from Weill Cornell Medicine. He completed a general surgery residency in 1987 at Roosevelt Hospital (now Mount Sinai West). [9] In 1988 he completed a fellowship in colon and rectal surgery at the University of Minnesota Medical School in Minneapolis, MN.

Career

In 1993, Wexner was named Chairman of the Department of Colorectal Surgery at Cleveland Clinic Florida. While at Cleveland Clinic he also served as Chairman of the Division of Research and Education from 1996 to 2007, as well as Chief of Staff from 1997 to 2007. He served as Chief Academic Officer from 2007 to 2012. In 2012 He was appointed the Director of the Digestive Diseases Center. [10]

Wexner holds academic appointments as Affiliate Professor at Florida Atlantic University; Clinical Professor at Florida International University; Affiliate Professor of Surgery at the University of South Florida, Tampa, Florida; Clinical Professor of Surgery at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University; Affiliate Professor of Surgery at the University of Miami Miller School of Medicine; Professor of Surgery, University of Siena, Siena, Italy; Visiting professor, Faculty of Medicine, the Hebrew University of Jerusalem, Hadassah Medical Center, Jerusalem, Israel; and visiting professor at the University of Belgrade in Serbia. [11]

As a founder of the National Accreditation Program for Rectal Cancer (NAPRC). [12] he led a multi-faceted coalition to establish the accreditation program with the American College of Surgeon's Commission on Cancer. The NAPRC's goal is to implement nationwide educational and medical standards for the best treatment of rectal cancer. [13]

Innovation and research

In 2022, Cleveland Clinic Florida received a $5 million gift to fund Wexner's research. In recognition of their generous contribution, Cleveland Clinic Weston recognized the Shulmans by naming the Digestive Disease Center the Ellen Leifer Shulman and Steven Shulman Digestive Disease Center. [4]

In an interview with Local 10, Wexner shared that he has been seeing a higher frequency of colorectal cancer in younger patients, due to genetic drift as well as environmental and dietary factors. [14] This is often misdiagnosed until the disease has become advanced, and so Wexner recommends beginning regular colonoscopy screenings earlier than guidelines currently advise.

J-Pouch Procedures

Much of Wexner's work has been focused on improving surgical techniques for the avoidance of permanent stomas in patients with colorectal cancer, ulcerative colitis, and fecal incontinence. He introduced a popular modification to the technique for creating an ileo-anal pouch, or j-pouch for ulcerative colitis, in which double stapling is used in place of sutures to improve results. [15] He also popularized the colonic j-pouch for patients with rectal cancer. [16] The J-pouch, an alternative to a permanent ileostomy or colostomy, allows patients who have had their colons removed to continue to have regular bowel movements without an ostomy bag. This is now the standard of care for patients with rectal carcinoma across the country and world. [10]

Incontinence and Constipation Scores

The Wexner Incontinence Score is the most common score used to determine the severity of incontinence before and after surgery for anal incontinence. [17] The Wexner Incontinence Score is based on the research of Wexner and his associate J. Marcio N. Jorge, MD. The scoring system takes into account the frequency of incontinence, alterations a patient makes to cope with incontinence, and lifestyle modifications.

Wexner's research has also developed the Wexner Constipation Score, occasionally known as the Cleveland Clinic Constipation Score.[7] The score measures the severity of constipation by taking into consideration a number of factors, which his research found to correlate with objective physiologic findings. Information on these factors is collected from each patient's subjective reports, and they are given a score. This score allows for appropriate and consistent diagnosis and treatment. The factors include the frequency and completeness of bowel movements, the difficulty of evacuation, the type of assistance used (if any), the patient's level of pain, and duration of constipation. [18]

In 1996, Wexner and colleagues released a method of scoring perianal disease activity for patients with Crohn's Disease. The goal of the scoring system is to utilize a patient's medical history and the results of physical examination to predict the likelihood of success of surgical intervention. [19] Prior to the development of this method, doctors lacked reliable indices of disease activity or prognostic implications from surgery.

Patents

Honors and awards

In 1999, Wexner was awarded an FRCS from the Royal College of Surgeons in Edinburgh, Scotland. In 2000 he was awarded an FRCS ad eundum from the Royal College of Surgeons in England. In 2008 he was elected to the Royal College of Surgeons of England by a unanimous vote of its council. This is the highest distinction conferred by the council. In 2015, Wexner was awarded honorary membership in the European Surgical Association and the European Society of Coloproctology. [20]

In 2013, Wexner was awarded an honorary foreign membership in the Argentina Society of Coloproctology. In 2012, Wexner was awarded the degree of PhD honoris causa by the University of Belgrade. In 2003, The American Jewish Committee presented Wexner with the prestigious Maimonides Award. In 2013, he was awarded Professor Emeritus of I.M. Sechenov First Moscow State Medical University. In 2016, Wexner was recognized by Cleveland Clinic Florida as a Master Clinician. [20]

In 2017, Wexner was awarded an honorary membership into the Society of General Surgery of Peru, honorary fellowship in the Royal College of Surgeons in Ireland, and Honorary Clinical Senior Lecturer at the University College London. In 2019, Wexner was awarded an Honorary Fellowship by the Royal College of Physicians and Surgeons of Glasgow, Scotland. Wexner was elected as an Honorary Fellow of the Royal College of Surgeons of England in 2022. [20]

In 2022, Wexner was appointed as a visiting professor in the Department of Surgery and Cancer at Imperial College London and Honorary Consultant at Imperial College Healthcare NHS Trust. [20]

Professional memberships and positions

As of October 2020, Wexner is vice-chair of the Board of Regents of the American College of Surgeons. [8] Through this position he also serves as vice-chair of the executive committee of the Board of Regents, the vice-chair of the Finance Committee of the ACS, and the Regental Liaison to the ACS Board of Governors. [21]

From 2011 to 2012, Wexner served as president of the American Society of Colon and Rectal Surgeons, [22] for which he gave a Presidential Address in 2012. [23] Prior to that, from 2010 to 2011 he served as president of the American Board of Colon and Rectal Surgery. [24] He also served as president of the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) from 2006 to 2007. [25] In 2007 he delivered the SAGES Presidential Address entitled "Trials and tribulations in the history of surgical innovation." [26]

Additionally, Wexner served on the Board of Regents of the American College of Surgeons from 2012 to 2021. [27] Within this organization he is on the executive committee for the Commission on Cancer. [28] He is also the chair of the National Accreditation Program for Rectal Cancer and was reappointed in 2023. [29]

Wexner has served as the president of other professional organizations, including the American Society of Colon and Rectal Surgeons Research Foundation, the Florida Gastroenterologic Society, and South Florida Chapter of the American College of Surgeons. [6] In addition to being licensed in the United States, Wexner is licensed in the United Kingdom with the General Medical Council and he is listed as a Colorectal Surgeon on the specialist register. [30]

In 2024, Wexner was named as an Honorary Fellow for The Society of Black Academic Surgeons. [31]

Publications

Wexner is the co-editor-in-chief of Surgery. [32] He has served on the editorial team for over 25 textbooks and has published 250 textbook chapters. He is a reviewer for 31 journals and is on 33 editorial boards. Wexner has authored numerous articles over his career.

In 2019, the Journal of Coloproctology published an analysis of the top 100 cited papers in benign anorectal disease which listed Wexner as the second most cited author. His paper with Marcio Jorge, Jorge, Marcio J. N.; Wexner, Steven D. (1993). "Etiology and Management of Fecal Incontinence". Diseases of the Colon & Rectum. 36 (1): 77–97. doi:10.1007/BF02050307. PMID   8416784. S2CID   37223486. was ranked as the most cited paper on benign anorectal disease. [33]

On October 19, 2021, Elsevier published a list of the top cited scientists from 198 different fields and sub-fields based on the Scopus database. In the field of surgery, Wexner was ranked as the 34th most cited author of all time. In the field of Colorectal Surgery, Wexner is the 3rd most cited author of all time and the most cited living colorectal surgery author. [34] As of September 2022, Dr. Wexner remained the most cited actively practicing colorectal surgery author in the world and the 21st most cited actively practicing surgeon in any specialty in the world. [35] As of May 2024, his H Index is 117 and he has authored 974 peer-reviewed publications. [36]

In his capacity as Regent for the American College of Surgeons, Wexner has also conducted a series of interviews with other surgeons from around the world called A Surgeon's Voice. [37] The interviews focus on these surgeons' experiences with the COVID-19 pandemic and their unique perspectives as medical professionals. He has produced over 100 videos which have received over 300,000 views, as of May 2020. [37] This series includes an interview with Johnson & Johnson CEO, Alex Gorsky, on the process of developing their COVID-19 vaccine. [38]

Wexner also published studies which resulted in the eponymous Wexner Incontinence Score and the Wexner Constipation Score, as well as the Pilarsky Wexner Perianal Crohn's Score:

Selected books

Selected articles

As noted above, Wexner has published a myriad of articles in scientific journals and books, including over 780 manuscripts and 26 editorials or commentaries in the last twenty years. [39] [40] Most recently, he co-authored the following noteworthy articles on COVID, on the contributions of women to the field of colorectal surgery, and on racial disparities in colorectal surgery outcomes:

In addition to the articles above, some of Dr. Wexner's more recent articles are listed below:

AIS Channel

Wexner is a contributor for the AIS (Advances in Surgery) Channel, a leading global educational platform providing training and networking for surgeons. [41] Since 2014, AIS has provided audiovisual recordings and broadcasts of procedures, techniques, and new developments in the world of surgery. AIS works with a constantly growing network of hospitals and key opinion leaders and validating academic and scientific societies. Wexner has been involved in dozens of broadcasts with topics ranging from robotic colorectal surgery teaching techniques to discussing diversity, equity, and inclusion issues in healthcare. [41]

Personal life

Wexner's father was Judge Ira Wexner, who presided in New York for over twenty years and lived part time in West Boca. [42] Wexner's spouse, Mariana Berho, M.D., is Chief of Staff at Cleveland Clinic Weston and also serves on the Board of Governors and Board of Trustees at the parent organization, Cleveland Clinic. [43]

Related Research Articles

<span class="mw-page-title-main">Hemorrhoid</span> Vascular structures in the anal canal

Hemorrhoids, also known as piles, are vascular structures in the anal canal. In their normal state, they are cushions that help with stool control. They become a disease when swollen or inflamed; the unqualified term hemorrhoid is often used to refer to the disease. The signs and symptoms of hemorrhoids depend on the type present. Internal hemorrhoids often result in painless, bright red rectal bleeding when defecating. External hemorrhoids often result in pain and swelling in the area of the anus. If bleeding occurs, it is usually darker. Symptoms frequently get better after a few days. A skin tag may remain after the healing of an external hemorrhoid.

<span class="mw-page-title-main">Fecal incontinence</span> Inability to refrain from defecation

Fecal incontinence (FI), or in some forms, encopresis, is a lack of control over defecation, leading to involuntary loss of bowel contents — including flatus (gas), liquid stool elements and mucus, or solid feces. FI is a sign or a symptom, not a diagnosis. Incontinence can result from different causes and might occur with either constipation or diarrhea. Continence is maintained by several interrelated factors, including the anal sampling mechanism, and incontinence usually results from a deficiency of multiple mechanisms. The most common causes are thought to be immediate or delayed damage from childbirth, complications from prior anorectal surgery, altered bowel habits. An estimated 2.2% of community-dwelling adults are affected. However, reported prevalence figures vary. A prevalence of 8.39% among non-institutionalized U.S adults between 2005 and 2010 has been reported, and among institutionalized elders figures come close to 50%.

<span class="mw-page-title-main">Colorectal cancer</span> Cancer of the colon or rectum

Colorectal cancer (CRC), also known as bowel cancer, colon cancer, or rectal cancer, is the development of cancer from the colon or rectum. Signs and symptoms may include blood in the stool, a change in bowel movements, weight loss, abdominal pain and fatigue. Most colorectal cancers are due to lifestyle factors and genetic disorders. Risk factors include diet, obesity, smoking, and lack of physical activity. Dietary factors that increase the risk include red meat, processed meat, and alcohol. Another risk factor is inflammatory bowel disease, which includes Crohn's disease and ulcerative colitis. Some of the inherited genetic disorders that can cause colorectal cancer include familial adenomatous polyposis and hereditary non-polyposis colon cancer; however, these represent less than 5% of cases. It typically starts as a benign tumor, often in the form of a polyp, which over time becomes cancerous.

<span class="mw-page-title-main">Anal fissure</span> Break or tear in anal canal skin

An anal fissure is a break or tear in the skin of the anal canal. Anal fissures may be noticed by bright red anal bleeding on toilet paper and undergarments, or sometimes in the toilet. If acute they are painful after defecation, but with chronic fissures, pain intensity often reduces and becomes cyclical.

<span class="mw-page-title-main">Rectal prolapse</span> Protrusion of the walls of the rectum outside the body

A rectal prolapse occurs when walls of the rectum have prolapsed to such a degree that they protrude out of the anus and are visible outside the body. However, most researchers agree that there are 3 to 5 different types of rectal prolapse, depending on whether the prolapsed section is visible externally, and whether the full or only partial thickness of the rectal wall is involved.

<span class="mw-page-title-main">Colorectal surgery</span> Field in medicine for disabilities in the rectum

Colorectal surgery is a field in medicine dealing with disorders of the rectum, anus, and colon. The field is also known as proctology, but this term is now used infrequently within medicine and is most often employed to identify practices relating to the anus and rectum in particular. The word proctology is derived from the Greek words πρωκτός proktos, meaning "anus" or "hindparts", and -λογία -logia, meaning "science" or "study".

In medicine, the ileal pouch–anal anastomosis (IPAA), also known as restorative proctocolectomy (RPC), ileal-anal reservoir (IAR), an ileo-anal pouch, ileal-anal pullthrough, or sometimes referred to as a J-pouch, S-pouch, W-pouch, or a pelvic pouch, is an anastomosis of a reservoir pouch made from ileum to the anus, bypassing the former site of the colon in cases where the colon and rectum have been removed. The pouch retains and restores functionality of the anus, with stools passed under voluntary control of the person, preventing fecal incontinence and serving as an alternative to a total proctocolectomy with ileostomy.

<span class="mw-page-title-main">Proctocolectomy</span> Surgical removal of the colon and rectum

Proctocolectomy is the surgical removal of the entire colon and rectum from the human body, leaving the patients small intestine disconnected from their anus. It is a major surgery that is performed by colorectal surgeons, however some portions of the surgery, specifically the colectomy may be performed by general surgeons. It was first performed in 1978 and since that time, medical advancements have led to the surgery being less invasive with great improvements in patient outcomes. The procedure is most commonly indicated for severe forms of inflammatory bowel disease such as ulcerative colitis and Crohn's disease. It is also the treatment of choice for patients with familial adenomatous polyposis.

Total mesorectal excision (TME) is a standard surgical technique for treatment of rectal cancer, first described in 1982 by Professor Bill Heald at the UK's Basingstoke District Hospital. It is a precise dissection of the mesorectal envelope comprising rectum containing the tumour together with all the surrounding fatty tissue and the sheet of tissue that contains lymph nodes and blood vessels. Dissection is along the avascular alveolar plane between the presacral and mesorectal fascia, described as holy plane. Dissection along this plane facilitates a straightforward dissection and preserves the sacral vessels and hypogastric nerves and is a sphincter-sparing resection and decreases permanent stoma rates. It is possible to rejoin the two ends of the colon; however, most patients require a temporary ileostomy pouch to bypass the colon, allowing it to heal with less risk of infection, perforation or leakage.

A lower anterior resection, formally known as anterior resection of the rectum and colon and anterior excision of the rectum or simply anterior resection, is a common surgery for rectal cancer and occasionally is performed to remove a diseased or ruptured portion of the intestine in cases of diverticulitis. It is commonly abbreviated as LAR.

An enterocele is a herniation of a peritoneum-lined sac containing small intestine through the pelvic floor, between the rectum and the vagina. Enterocele is significantly more common in females, especially after hysterectomy.

<span class="mw-page-title-main">Anismus</span> Failure to relax the pelvic floor muscles during defecation

Anismus or dyssynergic defecation is the failure of normal relaxation of pelvic floor muscles during attempted defecation. It can occur in both children and adults, and in both men and women. It can be caused by physical defects or it can occur for other reasons or unknown reasons. Anismus that has a behavioral cause could be viewed as having similarities with parcopresis, or psychogenic fecal retention.

Obstructed defecation syndrome is a major cause of functional constipation, of which it is considered a subtype. It is characterized by difficult and/or incomplete emptying of the rectum with or without an actual reduction in the number of bowel movements per week. Normal definitions of functional constipation include infrequent bowel movements and hard stools. In contrast, ODS may occur with frequent bowel movements and even with soft stools, and the colonic transit time may be normal, but delayed in the rectum and sigmoid colon.

Fistulectomy is a surgical procedure where a surgeon completely removes a fistula, an abnormal tract that connects two hollow spaces of the body. In comparison to other procedural options of treating fistulae such as fistulotomies, where a fistula is cut open but not completely removed, and seton placement, where a rubber band seton is passed through the tract and left post-operation as a means to allow drainage of the fistula, fistulectomies are considered to be a more radical approach. The total removal of a fistula may damage nearby structures in the process.

<span class="mw-page-title-main">National Accreditation Program for Rectal Cancer</span>

The National Accreditation Program for Rectal Cancer (NAPRC) was formed to address the differences between patient outcomes in the United States as compared to Europe. According to the American College of Surgeons, outcomes for rectal cancer patients in Europe have for years been significantly better than for those in the U.S. Characterized by the use of multidisciplinary teams to make treatment decisions, the NAPRC standards aim to decrease the average circumferential resection margins, decrease the overall colostomy rate, and increase quality of life as reported by recovering patients.

<span class="mw-page-title-main">Conor P. Delaney</span> Irish-American colorectal surgeon and professor

Conor P. Delaney MD, MCh, PhD, FRCSI, FACS, FASCRS, FRCSI (Hon.) is an Irish-American colorectal surgeon, CEO and President of the Cleveland Clinic Florida, the Robert and Suzanne Tomsich Distinguished Chair in Healthcare Innovation, and Professor of Surgery at the Cleveland Clinic Lerner College of Medicine. He is also the current President of the American Society of Colon and Rectal Surgeons (ASCRS). He was previously Chairman of the Digestive Disease & Surgery Institute at the Cleveland Clinic. He is both a Fellow and Honorary Fellow of the Royal College of Surgeons in Ireland and a Fellow of both the American College of Surgeons and American Society of Colon and Rectal Surgeons.

Ralph John Nicholls, FRCS (Eng), EBSQ is a retired British colorectal surgeon, Emeritus Consultant Surgeon at St Mark's Hospital London and Professor of Colorectal Surgery, Imperial College London.

Low anterior resection syndrome is a complication of lower anterior resection, a type of surgery performed to remove the rectum, typically for rectal cancer. It is characterized by changes to bowel function that affect quality of life, and includes symptoms such as fecal incontinence, incomplete defecation or the sensation of incomplete defecation, changes in stool frequency or consistency, unpredictable bowel function, and painful defecation (dyschezia). Treatment options include symptom management, such as use of enemas, or surgical management, such as creation of a colostomy.

Ventral rectopexy is a surgical procedure for external rectal prolapse, internal rectal prolapse, and sometimes other conditions such as rectocele, obstructed defecation syndrome, or solitary rectal ulcer syndrome. The rectum is fixed into the desired position, usually using a biological or synthetic mesh which is attached to the sacral promontory. The effect of the procedure is correction of the abnormal descended position of the posterior compartment of the pelvis, reinforcement of the anterior (front) surface of the rectum, and elevation of the pelvic floor. In females, the rectal-vaginal septum is reinforced, and there is the opportunity to simultaneously correct any prolapse of the middle compartment. In such cases, ventral rectopexy may be combined with sacrocolpopexy. The surgery is usually performed laparoscopically.

A rectal stricture is a chronic and abnormal narrowing or constriction of the lumen of the rectum which presents a partial or complete obstruction to the movement of bowel contents. A rectal stricture is located deeper inside the body compared to an anal stricture. Sometimes other terms with wider meaning are used, such as anorectal stricture, colorectal stricture or rectosigmoid stricture.

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