Streptomyces is the largest genus of Actinomycetota, and the type genus of the family Streptomycetaceae. Over 700 species of Streptomyces bacteria have been described. As with the other Actinomycetota, streptomycetes are gram-positive, and have very large genomes with high GC content. Found predominantly in soil and decaying vegetation, most streptomycetes produce spores, and are noted for their distinct "earthy" odor that results from production of a volatile metabolite, geosmin. Different strains of the same species may colonize very diverse environments.
In organic chemistry, polyketides are a class of natural products derived from a precursor molecule consisting of a chain of alternating ketone and methylene groups: [−C(=O)−CH2−]n. First studied in the early 20th century, discovery, biosynthesis, and application of polyketides has evolved. It is a large and diverse group of secondary metabolites caused by its complex biosynthesis which resembles that of fatty acid synthesis. Because of this diversity, polyketides can have various medicinal, agricultural, and industrial applications. Many polyketides are medicinal or exhibit acute toxicity. Biotechnology has enabled discovery of more naturally-occurring polyketides and evolution of new polyketides with novel or improved bioactivity.
Natamycin, also known as pimaricin, is an antifungal medication used to treat fungal infections around the eye. This includes infections of the eyelids, conjunctiva, and cornea. It is used as eyedrops. Natamycin is also used in the food industry as a preservative.
Lincosamides are a class of antibiotics, which include lincomycin, clindamycin, and pirlimycin.
Streptomyces clavuligerus is a species of Gram-positive bacterium notable for producing clavulanic acid.
Kitasatospora aburaviensis is a bacterium species from the genus Kitasatospora which was isolated from soil from Aburabi from the Shiga Prefecture in Japan. Kitasatospora aburaviensis produces the antibiotics aburamycin and ablastmycin and the enzyme inhibitor ebelactone.
Streptomyces afghaniensis is a bacterium species from the genus of Streptomyces which has been isolated from soil in Afghanistan. Streptomyces afghaniensis produces the antibiotic taitomycin.
Streptomyces albofaciens is a bacterium species from the genus of Streptomyces which produces oxytetracycline, spiramycin, albopeptin A, albopeptin B and alpomycin.
Streptomyces bikiniensis is a bacterium species from the genus Streptomyces which has isolated from soil from the island Bikini atoll. Streptomyces bikiniensis produces streptomycin II and carboxypeptidase.
Streptomyces caelestis is a bacterium species from the genus of Streptomyces which has been isolated from soil in Utah in the United States. Streptomyces caelestis produces desalicetin, isocelesticetin B, caelesticetin, citreamicin θ A, citreamicin θ B, citreaglycon A and dehydrocitreaglycon.
Streptomyces diastaticus is an alkaliphilic and thermophilic bacterium species from the genus of Streptomyces. Streptomyces diastaticus produces oligomycin A, oligomycin C, rimocidin and the leukotriene-A4 hydrolase-inhibitor 8(S)-amino-2(R)-methyl-7-oxononanoic acid. Streptomyces diastaticus also produces gougerotin and diastaphenazine and the antibiotic ruticin.
Streptomyces durhamensis is a bacterium species from the genus of Streptomyces which has been isolated from soil from a tomato plant. Streptomyces durhamensis produces durhamycin and filipin.
Streptomyces griseocarneus is a bacterium species from the genus of Streptomyces which has been isolated from soil. Streptomyces griseocarneus produces hydroxystreptomycin, alboverticillin, sphingomyelinase C and rotaventin.
Streptomyces griseorubens is a bacterium species from the genus of Streptomyces which has been isolated from soil. Streptomyces griseorubens produces althiomycin. Streptomyces griseorubens produces matamycin and althiomycin.
Streptomyces laurentii is a bacterium species from the genus of Streptomyces which has been isolated from soil. Streptomyces laurentii produces thiostrepton.
Streptomyces lydicus is a bacterium species from the genus of Streptomyces which has been isolated from soil in the United States. Streptomyces lydicus produces actithiazic acid, natamycin, lydimycin, streptolydigin, and 1-deoxygalactonojirimycin. Streptomyces lydicus can be used as an agent against fungal plant pathogens like Fusarium, Pythium, Phytophthora, Rhizoctonia and Verticillum.
Streptomyces rishiriensis is a bacterium species from the genus of Streptomyces which has been isolated from soil in Hokkaido in Japan. Streptomyces rishiriensis produces coumermycin A1, notomycin, 2-chloroadenosine, phosphophenylalanarginine and lactonamycin.
Streptomyces rochei is a bacterium species from the genus of Streptomyces which has been isolated from soil in Russia. Streptomyces rochei produces borrelidin, butyrolactol A, butyrolactol B, uricase and streptothricin. Streptomyces rochei has antifungal activity against Fusarium oxysporum f.sp. lycopersici and Aspergillus fumigatus. Streptomyces rochei produces moenomycin and bambermycin. Streptomyces rochei produces amicetin A, amicetin B, amicetin C and streptolin. Streptomyces rochei produces endo-β-N-acetylglucosaminidase mithramycin, amicetin, bamicetin, and plicacetin.
Streptomyces roseiscleroticus is a bacterium species from the genus of Streptomyces which has been isolated from soil from the Gujarat State in India. Streptomyces roseiscleroticus produces sultriecin.
Streptomyces virginiae is a bacterium species from the genus of Streptomyces which has been isolated from soil. Streptomyces virginiae produces actithiazic acid, virginiamycins and cycloserine. Streptomyces virginiae also produces monensin A, monensin B, monensin C, monensin D, actithiazic acid.
