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Streptomyces is the largest genus of Actinobacteria and the type genus of the family Streptomycetaceae. Over 500 species of Streptomyces bacteria have been described. As with the other Actinobacteria, streptomycetes are gram-positive, and have genomes with high GC content. Found predominantly in soil and decaying vegetation, most streptomycetes produce spores, and are noted for their distinct "earthy" odor that results from production of a volatile metabolite, geosmin.
Anthracyclines is a class of drugs used in cancer chemotherapy that are extracted from Streptomyces bacterium. These compounds are used to treat many cancers, including leukemias, lymphomas, breast, stomach, uterine, ovarian, bladder cancer, and lung cancers. The first anthracycline discovered was daunorubicin, which is produced naturally by Streptomyces peucetius, a species of actinobacteria. Clinically the most important anthracyclines are doxorubicin, daunorubicin, epirubicin and idarubicin.
In enzymology, an alizarin 2-beta-glucosyltransferase is an enzyme that catalyzes the chemical reaction
Bohemic acid is a mixture of chemical compounds which is obtained through fermentation by actinobacteria species in the genus Actinosporangium (Actinoplanaceae). The name honors the Puccini opera La Bohème and many individual components of the acid carry the names of characters from La Bohème. Most of those components are antitumor agents and anthracycline antibiotics active against Gram-positive bacteria.
Duclauxin is a chemical compound isolated from Penicillium duclauxi.
Penicillium cyaneum is a species of the genus of Penicillium which was isolated from an oil-field. Penicillium cyaneum produces fatty acid, Brefeldin A and the antibiotic Cyanein
Streptomyces atroolivaceus is a bacterium species from the genus of Streptomyces which has been isolated from soil in Russia. Streptomyces atroolivaceus produces leinamycin, mithramycin and chromocyclomycin.
Streptomyces caelestis is a bacterium species from the genus of Streptomyces which has been isolated from soil in Utah in the United States. Streptomyces caelestis produces desalicetin, isocelesticetin B, caelesticetin, citreamicin θ A, citreamicin θ B, citreaglycon A and dehydrocitreaglycon.
Streptomyces cinnamonensis is a bacterium species from the genus of Streptomyces. Streptomyces cinnamonensis produces monensin A, monensin B, monensin C, monensin D, actithiazic acid.
Streptomyces coeruleorubidus is a bacterium species from the genus of Streptomyces which has been isolated from marine sediment. Streptomyces coeruleorubidus produces the following medications: pacidamycin 1, baumycin B1, baumycin B2, baumycin C1, feudomycin A, feudomycin B, feudomycin C, ficellomycin, feudomycinone A, and rubomycin.
Streptomyces corchorusii is a bacterium species from the genus of Streptomyces which has been isolated from soil. Streptomyces corchorusii produces butalactin.
Streptomyces diastatochromogenes is a bacterium species from the genus of Streptomyces. Streptomyces diastatochromogenes produces polyketomycin, concanamycin A, concanamycin B, concanamycin C, momofulvenone A, azdimycin, toyocamycin and oligomycins.
Streptomyces galbus is a bacterium species from the genus of Streptomyces which has been isolated from soil from West Bengal. Streptomyces galbus produces xylanase, galbonolides A, galbonolides B and the actinomycin X complex.
Streptomyces griseoruber is a bacterium species from the genus of Streptomyces which has been isolated from soil in Japan. Streptomyces griseoruber produces beromycin, actinomycin D, gombapyrone A, gombapyrone B, gombapyrone C, gombapyrone D and rhodomycins
Streptomyces netropsis is a bacterium species from the genus of Streptomyces. Streptomyces netropsis produces the antibiotics netropsin and distamycin A and the antifungal polyene mycoheptin
Streptomyces orinoci is a bacterium species from the genus of Streptomyces which has been isolated from soil. Streptomyces orinoci produces the antibiotics spectinabilin, neoantimycin, neoaureothin and ochramycin.
Streptomyces plicatus is a bacterium species from the genus of Streptomyces. Streptomyces plicatus produces endo-β-N-acetylglucosaminidase mithramycin, amicetin, bamicetin and plicacetin.
Streptomyces purpurascens is a bacterium species from the genus of Streptomyces which has been isolated from soil. Streptomyces purpurascens produces α-l-arabinofuranosidase, isorhodomycin A, rhodomycin A and rhodomycin B.
Streptomyces sioyaensis is a bacterium species from the genus of Streptomyces which has been isolated from soil. Streptomyces sioyaensis produces siomycine and altemicidin.
Streptomyces virens is a bacterium species from the genus of Streptomyces. Streptomyces virens produces virenomycin.
References
- 1 2 LPSN bacterio.net
- ↑ Straininfo of Streptomyces glomeratus
- ↑ Deutsche Sammlung von Mikroorganismen und Zellkulturen
- ↑ UniProt
- ↑ Blumauerová, M; Podojil, M; Gauze, GF; Maksimova, TS; Panos, J; Vanĕk, Z (1980). "Spontaneous variability of Streptomyces glomeratus, a producer of the amthracycline antibiotics beromycins". Folia microbiologica. 25 (3): 207–12. doi:10.1007/bf02877339. PMID 7399371.
- ↑ Gauze, GF; Brazhnikova, MG; Borisova, VN; Maksimova, TS; Ol'khovatova, OL (June 1978). "[Formation of the anthracycline antibiotics, beromycin and nogalamycin, by a new actinomycete species, Streptomyces glomeratus sp. nov]". Antibiotiki. 23 (6): 483–9. PMID 677831.
- ↑ Roberts, edited by B.W. Bycroft ; contributors, A.A. Higton, A.D. (1988). Dictionary of antibiotics and related substances. London: Chapman and Hall. ISBN 0-412-25450-6.CS1 maint: extra text: authors list (link)
