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| Established | 1941 |
|---|---|
| Faculty | 60+ |
| Staff | 360+ |
| Location | , , USA* |
| Website | www |
Texas Biomedical Research Institute (Texas Biomed), located in San Antonio, Texas, is an independent, non-profit biomedical research institution, specializing in genetics and in virology and immunology. Texas Biomed is funded by government and corporate grants and contracts, and donations from the public.
Texas Biomed was founded in 1941 by Tom Slick as the Foundation of Applied Research. [1] [2] Its initial mission was to provide research and advanced education in agriculture, natural sciences and medicine. It became the Southwest Foundation for Research and Education in 1952. In the late 1950s, the Institute moved to its current location on Military Drive. In 1982, The Foundation was renamed Southwest Foundation for Biomedical Research (SFBR) and Texas Biomedical Research Institute on February 1, 2011.
Tom Slick’s sister, Betty Moorman, helped establish a club whose members could make an annual contribution to support the Foundation’s research. In the 1950s, the Foundation purchased an historic 1854 mansion in San Antonio called The Argyle to serve as the headquarters. [3] Members of the club continue to meet and support scientific research at Texas Biomed today with their time and resources. A group of women called the Texas Biomedical Forum raises money to support pilot grants for Texas Biomed scientists, science awards for outstanding teachers, and tours of the Institute for high school students.
In 1988, the Founders Council formed. It includes supporters ages 25 to 46 who support the Institute are community advocates and financial supporters. The Founders Council also provides grants for equipment to Texas Biomed scientists.
Located on a 200-acre (0.81 km2) campus on the northwest side of San Antonio, Texas Biomed employs over 60 doctoral level biomedical scientists, including 18 principal investigators and 360+ staff members. Focused on basic biomedical research, the Institute is divided into the Department of Genetics and the Department of Virology & Immunology. The Southwest National Primate Research Center, a part of Texas Biomed, is an international resource that provides specialized facilities and expertise in research with nonhuman primates to investigators from around the US and other countries. It maintains 2,500 nonhuman primates.
Texas Biomed maintains the only privately owned Biosafety level 4 (BSL-4) laboratory in the United States, developing bioterrorism defenses and novel strategies against incurable infectious diseases. [4] [5] [6]
The AT&T Genomics Computing Center, "the world's largest computer cluster devoted to statistical genetic analysis,"[ citation needed ] helps scientists find genes that influence susceptibility to diseases at record speed.
On April 14, 2018, four baboons escaped from the facility. They were contained within the same day. [15]
In 2015, it was announced that the institute is under a federal investigation after the death of at least five primates over a five-year period. According to news reports, one monkey was crushed to death by a cage door, another died from strangulation, and another from blood poisoning following a traumatic injury. [16] [17]
In 2014, the Humane Society of the United States released undercover footage from inside the institute which, according to the animal welfare group, “found a pattern of animal mistreatment, including overcrowding and lack of veterinary care”. [18] The group said their investigation found animals suffering from severe stress and improper treatment after injuries. In response, the institute argued they have “a long-standing commitment to treating animals humanely and with the highest regard for their well-being, and […] continuously seek to enhance the care provided to” the animals in their facility. [18]
Between 2012 and 2015, the institute was cited by federal inspectors for at least 16 alleged violations of the Animal Welfare Act. [17] In 2012, the institute was fined $25,714 for alleged violations and two years prior it paid a $6,094 settlement to the government for additional alleged violations. [17] The institute says the alleged violations are a result of isolated incidents and are not reflective of their treatment of the monkeys in their laboratories. [17]
This is a timeline of the development of prophylactic human vaccines. Early vaccines may be listed by the first year of development or testing, but later entries usually show the year the vaccine finished trials and became available on the market. Although vaccines exist for the diseases listed below, only smallpox has been eliminated worldwide. The other vaccine-preventable illnesses continue to cause millions of deaths each year. Currently, polio and measles are the targets of active worldwide eradication campaigns.
The Biomedical Primate Research Centre (BPRC) is Europe's largest primate animal testing research centre. It is a scientific research institute that performs research that contributes to the identification and development of new medicines against deadly diseases. It is located in Rijswijk and employs about 110 people.
Instituto Butantan is a Brazilian biologic research center located in Butantã, in the western part of the city of São Paulo, Brazil. Instituto Butantan is a public institution affiliated with the São Paulo State Secretariat of Health and considered one of the major scientific centers in the world. Butantan is the largest immunobiologicals and biopharmaceuticals producer in Latin America. It is world-renowned for its collection of venomous snakes, as well as those of venomous lizards, spiders, insects and scorpions. By extracting the reptiles' and insects' venoms, the Institute develops antivenoms and medicines against many diseases, which include tuberculosis, rabies, tetanus and diphtheria.
The Emory National Primate Research Center located in Atlanta, Georgia, owned by Emory University, is a center of biomedical and behavioral research, is dedicated to improving human and animal health, and is the oldest of seven National Primate Research Centers partially funded by the National Institutes of Health. It is known for its nationally and internationally recognized biomedical and behavioral studies with nonhuman primates by Emory University.
Since October 2018, the Center for Global Infectious Disease Research has been part of the Seattle Children's Research Institute. At the time of the merger, CID Research had 166 scientists. Its mission was to eliminate the world's most devastating infectious diseases through leadership in scientific discovery. The organization's research labs were in the South Lake Union area of Seattle, WA. The institute's research focused on four areas of infectious disease: HIV/AIDS, malaria, tuberculosis (TB), and Emerging & Neglected Diseases (END) like African sleeping sickness, leishmaniasis, Chagas disease, and toxoplasmosis. CID Research was engaged in early stages of the scientific pipeline including bench science and malaria clinical trials and has expertise in immunology, vaccinology, and drug discovery.
The Leibniz Institute of Virology was founded in 1948 by Heinrich Pette, a German neurologist. It began as a research facility to create a polio vaccine. It is now a private foundation and involved with basic research in virology and the immune responses of organisms. The institute is a non-profit public beneficiary organisation and an independent member of the Leibniz Association, located in Hamburg.
The Foundation for Biomedical Research (FBR) is an American nonprofit organization, 501(c)(3), located in Washington, DC. Established in 1981, the organization is dedicated to informing the news media, teachers, and other groups about the need for lab animals in medical and scientific research. The organization, together with its partner, the National Association for Biomedical Research (NABR), argues that promoting animal research leads to improved health for both humans and animals.
Experiments involving non-human primates (NHPs) include toxicity testing for medical and non-medical substances; studies of infectious disease, such as HIV and hepatitis; neurological studies; behavior and cognition; reproduction; genetics; and xenotransplantation. Around 65,000 NHPs are used every year in the United States, and around 7,000 across the European Union. Most are purpose-bred, while some are caught in the wild.
The National Institute of Virology in Pune, India is an Indian virology research institute and part of the Indian Council of Medical Research (ICMR). It was previously known as 'Virus Research Centre' and was founded in collaboration with the Rockefeller Foundation. It has been designated as a WHO H5 reference laboratory for SE Asia region.
The Wadsworth Center, located in Albany, New York, is the research-intensive public health laboratory of the New York State Department of Health.
Anthony (Tony) Charles Minson, PhD, FMedSci is a British virologist known for his work on the biology of herpesviruses, and a university administrator. He was the Senior Pro-Vice-Chancellor of the University of Cambridge from 2003 to 2009. He is emeritus professor of virology at the university's Department of Pathology and an emeritus fellow of Wolfson College.
Lisa Ellen Hensley is the Associate Director of Science at the Office of the Chief Scientist, National Institute of Allergy and Infectious Disease Integrated Research Facility in Frederick, Maryland. She was previously a civilian microbiologist in the virology division of the United States Army Medical Research Institute of Infectious Diseases (USAMRIID). Hensley is one of the premier researchers of some of the world's most dangerous infections, including Ebola hemorrhagic fever, Lassa fever, the coronavirus diseases Severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS), and smallpox. She has been involved in research uncovering critical mechanisms in the pathogenesis of hemorrhagic fever viruses, and has used those discoveries to develop candidate therapeutic drugs for their treatment.
Enzo Paoletti was an Italian-American virologist who developed the technology to express foreign antigens in vaccinia and other poxviruses. This advance led to the development of vaccines against multiple disease-causing pathogens.
Naval Medical Research Unit Six (NAMRU-6) is a biomedical research laboratory of the US Navy located in Lima, Peru. It is the only US military command located in South America. Its mission is to identify infectious diseases threats of military and public health importance and to develop and evaluate interventions and products to mitigate those threats.
Herpes simplex research includes all medical research that attempts to prevent, treat, or cure herpes, as well as fundamental research about the nature of herpes. Examples of particular herpes research include drug development, vaccines and genome editing. HSV-1 and HSV-2 are commonly thought of as oral and genital herpes respectively, but other members in the herpes family include chickenpox (varicella/zoster), cytomegalovirus, and Epstein-Barr virus. There are many more virus members that infect animals other than humans, some of which cause disease in companion animals or have economic impacts in the agriculture industry.
Ronald C. Kennedy was a virus immunologist at Texas Tech University. Prior to his appointment there he was affiliated with Baylor University, where he had previously done postdoctoral studies. Furthermore, when he switched affiliations to Texas Tech, he was also an adjunct, associate and full professor in the Departments of Microbiology and Pediatrics at the University of Texas Health Science Center at San Antonio. After his tenure in San Antonio, he switched affiliations to the University of Oklahoma Health Sciences Center's department of microbiology and immunology. In the 1980s he was affiliated with the Southwest Foundation for Biomedical Research, during which time he published some research pertaining to SV40 and intracellular protein transport. More recently, Kennedy has published some research regarding DNA vaccination, mostly in the journal Cancer Immunology, Immunotherapy.
The Armed Forces Research Institute of Medical Sciences (AFRIMS) is a United States Army project that started as a collaboration with the Government of Thailand to fight a cholera outbreak in Bangkok in 1958 and 1959. It subsequently expanded to conduct military medical research, primarily involving infectious diseases, across much of Southeast Asia and the Indian Subcontinent.
Robert Harry Purcell is an American virologist and former co-chief of the Laboratory of Infectious Diseases at the U.S. National Institute of Allergy and Infectious Disease. He is known for his work on hepatitis viruses, and was involved in identifying hepatitis A virus, hepatitis D virus, and hepatitis E virus, developing an animal model for hepatitis B, and developing the hepatitis A vaccine.
The Southwest National Primate Research Center (SNPRC) is a federally funded biomedical research facility affiliated with the Texas Biomedical Research Institute. The SNPRC became the seventh National Primate Research Center in 1999.
Christine Rollier is a French-British immunologist who is a professor at the University of Surrey. She focusses on the development of viral vector vaccines to treat infectious diseases. In particular, Rollier has focussed on the development of vaccinations to eliminate the plague.
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