Interstate 37 (I-37) is a 143-mile (230 km) Interstate Highway located within the southern portion of the US state of Texas. The highway was first designated in 1959 as a route between Corpus Christi and San Antonio. Construction in the urban areas of Corpus Christi and San Antonio began in the 1960s, and the segments of the Interstate Highway in rural areas were completed by the 1980s. Prior to I-37, the route between Corpus Christi and San Antonio was served by a combination of State Highway 9 (SH 9) from Corpus Christi to Three Rivers and U.S. Highway 281 (US 281) from Three Rivers to San Antonio. As a result of the construction of I-37, SH 9 was removed from the State Highway System.
U.S. Highway 181 is a south–north U.S. Highway located entirely in the state of Texas. Both termini are at Interstate 37, the road that it mainly parallels to the east. US 181 begins in Corpus Christi, Texas at mile marker 0 to the south, through south-central Texas to just south of San Antonio to the north, for a total length of 137 miles (220 km).
U.S. Route 77 is a major north–south United States Numbered Highway which extends for 1,305 miles (2,100 km) in the central United States. As of 2005, Its southern terminus is in Brownsville, Texas, at Veteran's International Bridge on the Mexican border, where it connects with both Mexican Federal Highway 101 and Mexican Federal Highway 180, and the highway's northern terminus is in Sioux City, Iowa, at an interchange with Interstate 29 (I-29).
U.S. Route 290 is an east–west U.S. Highway located entirely within the state of Texas. Its western terminus is at Interstate 10 southeast of Segovia, and its eastern terminus is at Interstate 610 in northwest Houston. It is the main highway between Houston and Austin and is a cutoff for travelers wanting to bypass San Antonio on Interstate 10. Throughout its length west of Austin, US 290 cuts across mountainous hills comprising the Texas Hill Country and the Edwards Plateau; between Austin and Houston, the highway then travels through gradually hilly grasslands and pine forests comprising the Gulf Coastal Plains.
State Highway 35 is a largely north–south highway in southeastern and southern Texas between Houston, junction of I-45 on the southeast side of the city and Corpus Christi, where it terminates at I-37.
Loop 1604 is the outer highway loop encircling San Antonio, Texas, spanning approximately 95.6 miles (153.9 km). Originally constructed as a two-lane highway, the northern segment of the route, from US 90 in western San Antonio to Kitty Hawk Road in northeastern Bexar County, has been upgraded to a four-lane freeway. Loop 1604 is designated the Charles W. Anderson Loop in honor of former Bexar County Judge Charles W. Anderson, who died from cancer in 1964 after serving for 25 years.
State Highway 57 is a 1.474-mile (2.372 km) Texas state highway located in Tyler.
State Highway 100 is a Texas state highway that runs 24 miles (39 km) between "Russeltown" and Port Isabel. It was designated in 1926 along its current route. Its western terminus is at Interstate 69E/U.S. Highway 77/83 and ends at the western end of the Queen Isabella Memorial Causeway at Port Isabel. The route continues as Texas Park Road 100 east and north to a dead end on South Padre Island.
State Highway 234 is a short state highway connecting Edroy and Odem in San Patricio County, Texas.
State Highway 361 is a state highway in San Patricio and Nueces counties that runs from Gregory in southern Texas, near Corpus Christi, east and south to Padre Island on the Gulf of Mexico coast.
State Highway 286 is a Texas state highway running from downtown Corpus Christi south to Chapman Ranch. The route was designated on its current route in 1939. Before 1939, this route was known as SH 96, and was proposed to be extended to the southwest to Riviera. It is also locally known as the "Crosstown Expressway."
State Highway 357 is a Texas state highway that runs along the southwestern end of Corpus Christi. The route was originally designated as FM 692 on June 4, 1946. On September 5, 1946, it was redesignated to SH 357.
U.S. Route 77 (US 77) is a major highway that is part of the United States Numbered Highway System that runs from the Veterans International Bridge in Brownsville to Sioux City, Iowa. In Texas, the road runs south-north for 471.3 miles (758.5 km) from the International border with Mexico to the Oklahoma state line north of Gainesville. The highway is being upgraded to a freeway near Corpus Christi to connect to the freeway part of the highway in Raymondville as part of future I-69. A freeway in Robstown is already signed as part of I-69. From Waco to the Oklahoma state line, US 77 overlaps or runs parallel to I-35/I-35E.
U.S. Highway 75 (US 75) is a part of the U.S. Highway System that travels from Interstate 345 (I-345) in Dallas, Texas northward to the Canadian border at Noyes, Minnesota. In the state of Texas it runs from I-345 in Dallas and heads north to the Oklahoma state line.
Interstate 69 (I-69) is an Interstate Highway that is in the process of being built in the US state of Texas. It is part of a longer I-69 extension known as the NAFTA superhighway, that, when completed, will connect Canada to Mexico. In Texas, it will connect Tenaha and I-69 in Louisiana at the Louisiana border through the eastern part of the state and along the Texas Gulf Coast to Victoria, where it will split into three branches: I-69E to Brownsville, I-69C to Pharr, and I-69W to Laredo. The first segment of I-69 in Texas was opened in 2011 near Corpus Christi. The American Association of State Highway and Transportation Officials (AASHTO) approved an additional 58 miles (93 km) of US 77 from Brownsville to the Willacy–Kenedy county line for designation as I-69, which was to be signed as I-69E upon concurrence from the Federal Highway Administration (FHWA). FHWA approval for this segment was announced on May 29, 2013. By March 2015, a 74.9-mile (120.5 km) section of US 59 had been completed and designated as I-69 through Greater Houston. As of 2022, short segments near the southern terminuses of the three branch routes have also all been completed. These branches are planned to be connected.
Spur 69 is a short, unsigned, four-lane state-maintained roadway in Austin, Texas. It is 1.2 miles (1.9 km) in length and is named Koenig Lane. It forms a link between RM 2222 and US 290 at I-35. Spur 69 is signed over its entire length as RM 2222, rather than as Spur 69.
The John F. Kennedy Memorial Causeway is a paved highway located in Corpus Christi, Texas. The causeway crosses the Laguna Madre and connects North Padre Island with Flour Bluff on the Texas mainland.
Texas Park Road 22 is a major Park Road located in Nueces and Kleberg counties along the Gulf Coast region of the U.S. state of Texas. The highway is approximately 15.6 miles (25.1 km) in length, and is located mainly in the city of Corpus Christi, with a large portion of the roadway traveling along Padre Island. Most of the highway's length within Corpus Christi is built up to freeway standards.
Interstate 69E (I-69E) is a north–south freeway running through South Texas. Once complete, the freeway will begin in Brownsville and head northward before terminating near Victoria as both I-69W and I-69E merge into I-69 toward Houston. For its entire length, I-69E runs concurrently with U.S. Highway 77 (US 77). The route currently exists in two segments: a 56-mile (90 km) segment from its southern terminus in Brownsville to the Willacy–Kenedy county line and a shorter eight-mile (13 km) segment south of Corpus Christi. The route has one auxiliary Interstate route, I-169 in Brownsville.
Interstate 169 (I-169) is an auxiliary route of I-69E in Texas that currently runs from I-69E in Brownsville southeast concurrently with State Highway 550 (SH 550), a toll road under construction that connects to the Port of Brownsville for 1.5 miles (2.4 km). When SH 550 is complete, it will be a limited-access toll route around the northern and eastern edges of Brownsville and signed as I-169, partly replacing and expanding Farm to Market Road 511 (FM 511). Its purpose is to provide a new entry point for truck traffic to the Port of Brownsville and forming a loop that allows traffic to bypass the northern sections of the urbanized extent of the Brownsville city limits. This may serve as a relief route for future traffic congestion and as a future business corridor.
I-37 in Corpus Christi 
SH 44 in Corpus Christi
SH 286 in Corpus Christi
