The peripheral nervous system (PNS) is one of two components that make up the nervous system of bilateral animals, with the other part being the central nervous system (CNS). The PNS consists of the nerves and ganglia outside the brain and spinal cord. The main function of the PNS is to connect the CNS to the limbs and organs, essentially serving as a relay between the brain and spinal cord and the rest of the body. Unlike the CNS, the PNS is not protected by the vertebral column and skull, or by the blood–brain barrier, which leaves it exposed to toxins and mechanical injuries.
In vertebrates, thoracic vertebrae compose the middle segment of the vertebral column, between the cervical vertebrae and the lumbar vertebrae. In humans, there are twelve thoracic vertebrae and they are intermediate in size between the cervical and lumbar vertebrae; they increase in size going towards the lumbar vertebrae, with the lower ones being a lot larger than the upper. They are distinguished by the presence of facets on the sides of the bodies for articulation with the heads of the ribs, as well as facets on the transverse processes of all, except the eleventh and twelfth, for articulation with the tubercles of the ribs. By convention, the human thoracic vertebrae are numbered T1–T12, with the first one (T1) located closest to the skull and the others going down the spine toward the lumbar region.
The intercostal nerves are part of the somatic nervous system, and arise from the anterior rami of the thoracic spinal nerves from T1 to T11. The intercostal nerves are distributed chiefly to the thoracic pleura and abdominal peritoneum and differ from the anterior rami of the other spinal nerves in that each pursues an independent course without plexus formation.
Sympathetic ganglia are the ganglia of the sympathetic nervous system. They deliver information to the body about stress and impending danger, and are responsible for the familiar fight-or-flight response. They contain approximately 20,000–30,000 nerve cell bodies and are located close to and on either side of the spinal cord in long chains. Sympathetic ganglia are the tissue from which neuroblastoma tumours arise.
The lateral grey column is one of the three grey columns of the spinal cord ; the others being the anterior and posterior grey columns. The lateral grey column is primarily involved with activity in the sympathetic division of the autonomic motor system. It projects to the side as a triangular field in the thoracic and upper lumbar regions of the postero-lateral part of the anterior grey column.
The posterior thoracic nucleus, is a group of interneurons found in the medial part of lamina VII, also known as the intermediate zone, of the spinal cord. It is mainly located from the cervical vertebra C8 to lumbar L3-L4 levels and is an important structure for proprioception of the lower limb.
The ventral ramus is the anterior division of a spinal nerve. The ventral rami supply the antero-lateral parts of the trunk and the limbs. They are mainly larger than the dorsal rami.
The cervical spinal nerve 5 (C5) is a spinal nerve of the cervical segment.
The thoracic spinal nerve 1 (T1) is a spinal nerve of the thoracic segment.
The thoracic spinal nerve 2 (T2) is a spinal nerve of the thoracic segment.
The thoracic spinal nerve 3 (T3) is a spinal nerve of the thoracic segment.
The thoracic spinal nerve 4 (T4) is a spinal nerve of the thoracic segment.
The thoracic spinal nerve 5 (T5) is a spinal nerve of the thoracic segment.
The thoracic spinal nerve 6 (T6) is a spinal nerve of the thoracic segment.
The thoracic spinal nerve 7 (T7) is a spinal nerve of the thoracic segment.
The thoracic spinal nerve 8 (T8) is a spinal nerve of the thoracic segment.
The thoracic spinal nerve 9 (T9) is a spinal nerve of the thoracic segment.
The thoracic spinal nerve 11 (T11) is a spinal nerve of the thoracic segment.
The thoracic spinal nerve 12 (T12) is a spinal nerve of the thoracic segment.
