William T. Carpenter

Last updated
William T. Carpenter
NationalityAmerican
Education Wofford College
Wake Forest University
University of Rochester
Occupation(s) Psychiatrist
Clinician-Scientist
Known forResearch on Schizophrenia
Expert witness in the John W. Hinckley trial for attempted assassination of President Reagan

William T. Carpenter is an American psychiatrist, a pioneer in the fields of psychiatry and pharmacology who served as an expert witness in the John W. Hinckley trial for the attempted assassination of U.S. President Ronald Reagan. [1] [2] [3] [4] [5] [6] [7] [8] His primary professional interest is in severe mental illness, especially schizophrenia, to the prevention and treatment of which he has made significant contributions in psychopathology, assessment methodology, testing of new treatments, and research ethics. [1] [9]

Contents

Early life

Carpenter was raised in Rutherfordton, North Carolina, a farming community between Asheville and Charlotte, North Carolina. [2] A standout athlete at Wofford College in South Carolina, Carpenter's abilities on the football field attracted the attention of the Baltimore Colts during his senior year in 1957, and the team offered him an opportunity to play professional football on the same team as legendary quarterback Johnny Unitas. After talking to his family and his minister, Carpenter turned them down. The next year, the Colts won the Western Conference championship and went on to defeat the New York Giants in the first overtime game in National Football League history, often referred to as the "greatest game ever played". Carpenter went on to a career in medicine, devoting a 50-plus-year career to the understanding and treatment of severe mental illness. [2]

Medical career

Carpenter obtained his M.D. degree from the Wake Forest University School of Medicine. After an internship at the North Carolina Baptist Hospital, he took postgraduate training at the University of Rochester Medical Center. [1] He began his research career with the National Institute of Mental Health Intramural Program in 1966, using neuroendocrine strategies to study the psychobiology of affective disorders. [1]

In 1966, Carpenter took a psychiatric researcher position at the National Institute of Mental Health (NIMH) in Bethesda, Maryland, where he studied the psychobiology of affective disorders. [2] Following that, he became a collaborating investigator in the World Health Organization's International Pilot Study of Schizophrenia. [1] At the WHO study, Carpenter developed his interest in schizophrenia research, studying prognosis, diagnosis, and treatment outcomes. He continued his work at the Albert Einstein College of Medicine and Columbia University in New York City before joining the faculty of the University of Maryland School of Medicine in 1977 as professor of psychiatry and director of the Maryland Psychiatric Research Center. [2]

Carpenter has served as Editor-in-Chief for Schizophrenia Bulletin and on the editorial boards of the Archives of General Psychiatry , Biological Psychiatry , the Journal of Nervous and Mental Disease , Neuropsychopharmacology , Psychiatry Research , Schizophrenia Bulletin , Schizophrenia Research , Current Psychiatry Reports, and the CD-ROM version of the American College of Neuropsychopharmacology publication Neuropsychopharmacology: Fourth Generation of Progress. [1]

His special professional assignments include service on the National Institute of Mental Health (NIMH) Intramural Research Program Board of Scientific Counselors and as a consultant and reviewer for NIMH and National Institutes of Health (NIH) on many topics. [9] He has chaired the NIMH Research Scientist Career Development Committee and the NIMH National Plan Committee on Treatment Research and has been funded as principal investigator for NIMH center grants from 1986 to 2013. [1] He is the only scientist to direct both an NIMH-funded Clinical Research Center (now Intervention Research Center) and an NIMH-funded Center for Neuroscience and Schizophrenia. [9]

He is a past-president of the American College of Neuropsychopharmacology and participated in the founding of the National Alliance for Research on Schizophrenia and Depression, for which he has chaired its scientific program committee. [1]

Hinckley trial testimony

The trial of John Hinckley Jr. for attempting to assassinate President Ronald Reagan outside the Washington Hilton Hotel in 1981 and wounding the President, Press Secretary James Brady, a U.S. Secret Service agent and a police officer brought Carpenter into the national spotlight. As the defense psychiatrist, Carpenter interviewed Hinckley for a total of 45 hours and took the stand at the trial to provide a compelling three days of testimony. Hinkley was found not guilty by reason of insanity. Carpenter's testimony is credited with giving the field of psychiatry new credibility and increasing public awareness about severe mental illness. [2]

Honors and awards

Carpenter has been the recipient of 23 national and international research awards, was elected in 1998 to the Institute of Medicine of the National Academy of Sciences. [1] [9] and in 2019 received the SIRS Lifetime Achievement Award (Schizophrenia International Research Society) and the Pardes Humanitarian Prize in Mental Health (Brain and Behavior Research Foundation).

In addition to the U.S. Government v. John Hinckley case, Carpenter has provided expert testimony in the 1997 murder trial of John E. DuPont, and in 1989 was a member of the U.S. State Department delegation to inspect the political use of psychiatry in the Soviet Union. [1] [9]

He has authored over 400 clinical and scientific articles, books, and book chapters, [2] a select list of which can be viewed at the University of Maryland School of Medicine Faculty Profiles website, [9] and is in the top 0.5% of authors cited in his field. [10]

Related Research Articles

Edwin Fuller Torrey, is an American psychiatrist and schizophrenia researcher. He is associate director of research at the Stanley Medical Research Institute (SMRI) and founder of the Treatment Advocacy Center (TAC), a nonprofit organization whose principal activity is promoting the passage and implementation of outpatient commitment laws and civil commitment laws and standards in individual states that allow people diagnosed with mental illness to be forcibly committed and medicated easily throughout the United States.

<span class="mw-page-title-main">Adolf Meyer (psychiatrist)</span> Swiss-American psychiatrist (1866–1950)

Adolf Meyer was a Swiss-born psychiatrist who rose to prominence as the first psychiatrist-in-chief of the Johns Hopkins Hospital (1910-1941). He was president of the American Psychiatric Association in 1927–28 and was one of the most influential figures in psychiatry in the first half of the twentieth century. His focus on collecting detailed case histories on patients was one of the most prominent of his contributions. He oversaw the building and development of the Henry Phipps Psychiatric Clinic at Johns Hopkins Hospital, opened in April 1913, making sure it was suitable for scientific research, training and treatment. Meyer's work at the Phipps Clinic is possibly the most significant aspect of his career.

Loren Richard Mosher was an American psychiatrist, clinical professor of psychiatry, expert on schizophrenia and the chief of the Center for Studies of Schizophrenia in the National Institute of Mental Health (1968–1980). Mosher spent his professional career advocating for humane and effective treatment for people diagnosed as having schizophrenia and was instrumental in developing an innovative, residential, home-like, non-hospital, non-drug treatment model for newly identified acutely psychotic persons.

<span class="mw-page-title-main">Dennis S. Charney</span> American medical researcher

Dennis S. Charney is an American biological psychiatrist and researcher, with expertise in the neurobiology and treatment of mood and anxiety disorders. He is the author of Neurobiology of Mental Illness, The Physician's Guide to Depression and Bipolar Disorders and Molecular Biology for the Clinician, as well as the author of over 600 original papers and chapters. In 2022, he was listed #52 on Research.com's "Top Medicine Scientists in the United States," with an h-index of 194 with 146,109 citations across 651 publications. Charney is known for demonstrating that ketamine is effective for treating depression. Ketamine's use as a rapidly-acting anti-depressant is recognized as a breakthrough treatment in mental illness.

Steven Edward Hyman is Director of the Stanley Center for Psychiatric Research at the Broad Institute of MIT and Harvard in Cambridge, Massachusetts. He is also Harvard University Distinguished Service Professor of Stem Cell and Regenerative Biology. Hyman was Provost of Harvard University from 2001 to 2011 and before that Director of the U.S. National Institute of Mental Health (NIMH) from 1996 to 2001. Hyman received the 2016 Rhoda and Bernard Sarnat International Prize in Mental Health from the National Academy of Medicine for "leadership in furthering understanding and treatment of psychiatric disorders as biological diseases".

<span class="mw-page-title-main">Thomas R. Insel</span> American neuroscientist

Thomas Roland Insel is an American neuroscientist, psychiatrist, entrepreneur, and author who led the National Institute of Mental Health (NIMH) from 2002 until November 2015. Prior to becoming Director of NIMH, he was the founding Director of the Center for Behavioral Neuroscience at Emory University in Atlanta, Georgia. He is best known for research on oxytocin and vasopressin, two peptide hormones implicated in complex social behaviors, such as parental care and attachment. He announced on Sept. 15, 2015, that he was resigning as the director of the NIMH to join the Life Science division of Google X. On May 8, 2017, CNBC reported that he had left Verily Life Sciences. Insel is a Co-founder with Richard Klausner and Paul Dagum of a digital mental health company named "Mindstrong," a Bay-area startup. He has also co-founded Humanest Care, NeuraWell Therapeutics, and MindSite News and is a member of the scientific advisory board for Compass Pathways, a company that is developing the psychedelic drug psilocybin to treat depression and other mental health disorders. His book, Healing: Our Path from Mental Illness to Mental Health was published by Penguin Random House in February, 2022.

Susan Swedo is a researcher in the field of pediatrics and neuropsychiatry. Beginning in 1998, she was Chief of the Pediatrics & Developmental Neuroscience Branch at the US National Institute of Mental Health. In 1994, Swedo was lead author on a paper describing pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS), a controversial hypothesis proposing a link between Group A streptococcal infection in children and some rapid-onset cases of obsessive-compulsive disorder (OCD) or tic disorders such as Tourette syndrome. Swedo retired from the NIH in 2019, and serves on the PANDAS Physician Network.

<span class="mw-page-title-main">Jeffrey Lieberman</span> American psychiatrist (born 1948)

Jeffrey Alan Lieberman is an American psychiatrist who specializes in schizophrenia and related psychoses and their associated neuroscience (biology) and pharmacological treatment. He was principal investigator for CATIE, the largest and longest independent study ever funded by the United States National Institute of Mental Health to examine existing pharmacotherapies for schizophrenia. He was president of the American Psychiatric Association from May 2013 to May 2014.

Dilip V. Jeste is an American geriatric neuropsychiatrist, who specializes in successful aging as well as schizophrenia and other psychotic disorders in older adults. He was senior associate dean for healthy aging and senior care, distinguished professor of psychiatry and neurosciences, Estelle and Edgar Levi Memorial Chair in Aging, director of the Sam and Rose Stein Institute for Research on Aging, and co-director of the IBM-UCSD Artificial Intelligence Center for Healthy Living at the University of California, San Diego School of Medicine. after serving for 36 years, he retired from UC San Diego on July 1, 2022.

Celso Arango is a psychiatrist who has worked as a clinician, researcher, and educator in psychiatry and mental health, notably in the field of child and adolescent psychiatry, psychosis, and mental health promotion.

Joel Elkes was a leading medical researcher specialising in the chemistry of the brain. He qualified as a physician in London and later became a medical researcher who published the first double-blind scientific trial on chlorpromazine to treat schizophrenia. He is regarded as the father of modern neuropsychopharmacology and directed the first experimental psychiatric Uffculme Clinic in Birmingham, UK. He was responsible for the setting up of international organisations and university departments to further the investigation of the effects of psychopharmacy. He spent the latter part of his career endeavouring to bring higher levels of humanity, compassion and ethics to medical training.

The Schizophrenia Cognition Rating Scale (SCoRS) is a 20 item interview-based clinical assessment that evaluates cognitive deficits and the degree to which these deficits impair patients’ day-to-day functioning. It was originally developed in 2001 at the Duke University Medical Center by Dr. Richard Keefe and is licensed through VeraSci. The SCoRS is used in clinical trials, academic research, and in clinical settings.

<span class="mw-page-title-main">Judith L. Rapoport</span> American psychiatrist

Judith L. Rapoport is an American psychiatrist. She is the chief of the Child Psychiatry Branch at the National Institute of Mental Health (NIMH), part of the National Institutes of Health (NIH) in Bethesda, Maryland.

Daniel R. Weinberger is a professor of psychiatry, neurology and neuroscience at Johns Hopkins University and Director and CEO of the Lieber Institute for Brain Development, which opened in 2011.

John M. Kane is an American psychiatrist who served as the Chair of Psychiatry at the Zucker Hillside Hospital for 34 years. He also served as the Chair of Psychiatry at The Donald and Barbara Zucker School of Medicine at Hofstra/Northwell for its first 12 years. He stepped down from these roles in 2022 to focus his efforts on his research and mentorship of early career investigators as Co-Director, Institute of Behavioral Science at the Feinstein Institutes for Medical Research, part of Northwell Health.

<span class="mw-page-title-main">W. Wolfgang Fleischhacker</span> Austrian psychiatrist and academic

Walter Wolfgang Fleischhacker is an Austrian psychiatrist and psychotherapist. Previously professor of psychiatry at the Medical University Innsbruck, he was appointed president of the university 1 October 2017.

<span class="mw-page-title-main">Haim Belmaker</span> Israeli professor of psychiatry

Prof. Robert Haim Belmaker, is an Israeli psychiatrist who has had major academic positions in Israeli psychiatry since 1974. He had a formative influence on biological directions in Israeli psychiatry. He was Hoffer-Vickar Professor of Psychiatry at Ben-Gurion University of the Negev, Beersheva Israel until his retirement and is now Emeritus.

Joseph Thomas Coyle Jr. is an American psychiatrist and neuroscientist that is known for his work on the neurobiology of mental illness, more specifically on schizophrenia. He is currently the Eben S. Draper Chair of Psychiatry and Neuroscience at Harvard Medical School in Boston, Massachusetts. He was President of the Society of Neuroscience from 1991–1992, and also the president of the American College of Neuropsychopharmacology in 2001. He is a member of the Institute of Medicine.

David Rosenthal was an American psychologist known for his research on the relative genetic and environmental contributions to schizophrenia and other psychopathologies. He is particularly recognized for his research on the Genain quadruplets, and he led the team who studied the quadruplets intensively from 1955 to 1958. In 1976, then-NIMH director Bertram S. Brown described Rosenthal as "one of the top scientists in the area of the nature and etiology of schizophrenia." In the 1960s, he collaborated with Seymour Kety and other researchers on multiple adoption studies of schizophrenia that were conducted in Denmark.

Coordinated Specialty Care (CSC) is a recovery-oriented treatment program designed for people with first episode psychosis (FEP). CSC consists of collaborative treatment planning between the client and the client's care team, consisting of mental health clinicians, psychiatrists, and case managers. CSC includes individual and family therapy, medication management, psychoeducation and support, case management, and support surrounding education and employment goals. The program is considered an early psychosis intervention and is intended to be used shortly after symptoms onset.

References

  1. 1 2 3 4 5 6 7 8 9 10 APA DSM-V Task Force Member Disclosure Report, William T Carpenter, MD, 5/2/2011, http://www.dsm5.org/MeetUs/Documents/Task%20Force%202011/Carpenter%204-28-11.pdf, accessed March 4, 2012.
  2. 1 2 3 4 5 6 7 Schizophrenia: Seeking Solutions (Dr. William T. Carpenter, Jr. focusing on study of schizophrenia), Bulletin of the Medical Alumni Association of the University of Maryland, Inc., Spring, 2001, http://www.medicalalumni.org/bulletin/spring_2001/lead1.html, accessed March 4, 2012.
  3. "The Insanity Defense Has Little To Do With Science". www.nytimes.com. Retrieved 2023-02-14.
  4. "Excerpt's from the Hinckley Trial". law2.umkc.edu. Retrieved 2023-02-14.
  5. "Daily News - Google News Archive Search". news.google.com. Retrieved 2023-02-14.
  6. "Doctor Says Hinckley Sought Post-Life Union With Foster" in The [Palm Beach, Fla.] Post, Saturday, May 15, 1982, p. A6, https://news.google.com/newspapers?nid=1964&dat=19820515&id=lQItAAAAIBAJ&sjid=iM0FAAAAIBAJ&pg=1239,2218102, accessed March 4, 2012.
  7. The History Channel: The Plot to Kill Reagan, aired Thursday, March 30th, 2012, at 11:00 p.m. ET/PT, http://www.prnewswire.com/news-releases/the-plot-to-kill-reagan-on-the-history-channelr-55457887.html, accessed March 4, 2012.
  8. "Schenectady Gazette - Google News Archive Search". news.google.com. Retrieved 2023-02-14.
  9. 1 2 3 4 5 6 University of Maryland School of Medicine Faculty Profiles: William T Carpenter M.D., http://medschool.umaryland.edu/facultyresearchprofile/viewprofile.aspx?id=2266, accessed March 4, 2012.
  10. Thomson Reuters Highly Cited Research, formerly Thomson ISI, Institute for Scientific Information: The People Behind the World's Most Influential Research, http://highlycited.com/names/C.html, accessed 4 Jul 2013.