Complex and mixed tumor

Last updated
Complex and mixed tumor
Specialty Oncology

A mixed tumor is a tumor derived from one cell type that has divergent differentiation. [1]

Contents

Examples include pleomorphic adenoma and Mixed Müllerian tumor.

Pleomorphic adenoma gastrointestinal benign neoplasm that is a located in the salivary glands

Pleomorphic adenoma is a common benign salivary gland neoplasm characterised by neoplastic proliferation of parenchymatous glandular cells along with myoepithelial components, having a malignant potentiality. It is the most common type of salivary gland tumor and the most common tumor of the parotid gland. It derives its name from the architectural Pleomorphism seen by light microscopy. It is also known as "Mixed tumor, salivary gland type", which refers to its dual origin from epithelial and myoepithelial elements as opposed to its pleomorphic appearance.

Mixed Müllerian tumor

A malignant mixed Müllerian tumor, also known as malignant mixed mesodermal tumor (MMMT) is a cancer found in the uterus, the ovaries, the fallopian tubes and other parts of the body that contains both carcinomatous and sarcomatous components. It is divided into two types, homologous and a heterologous type. MMMT account for between two and five percent of all tumors derived from the body of the uterus, and are found predominantly in postmenopausal women with an average age of 66 years. Risk factors are similar to those of adenocarcinomas and include obesity, exogenous estrogen therapies, and nulliparity. Less well-understood but potential risk factors include tamoxifen therapy and pelvic irradiation.

See also

Related Research Articles

Testicular cancer male reproductive system cancer that is located in the testicles

Testicular cancer is cancer that develops in the testicles, a part of the male reproductive system. Symptoms may include a lump in the testicle, or swelling or pain in the scrotum. Treatment may result in infertility.

Choriocarcinoma Human disease

Choriocarcinoma is a malignant, trophoblastic cancer, usually of the placenta. It is characterized by early hematogenous spread to the lungs. It belongs to the malignant end of the spectrum in gestational trophoblastic disease (GTD). It is also classified as a germ cell tumor and may arise in the testis or ovary.

Sertoli–Leydig cell tumour Human disease

Sertoli–Leydig cell tumour is a group of tumors composed of variable proportions of Sertoli cells, Leydig cells, and in the case of intermediate and poorly differentiated neoplasms, primitive gonadal stroma and sometimes heterologous elements.

Dysgerminoma germ cell cancer that derives from cells that give rise to egg cells

A dysgerminoma is a type of germ cell tumor; it usually is malignant and usually occurs in the ovary.

Germ cell tumor Rare germ cell tumor

A germ-cell tumor (GCT) is a neoplasm derived from germ cells. Germ-cell tumors can be cancerous or benign. Germ cells normally occur inside the gonads. GCTs that originate outside the gonads may be birth defects resulting from errors during development of the embryo.

Dermatofibrosarcoma protuberans A fibrosarcoma that is located in the dermis laryer of the skin and that begins as a hard nodule and grows slowly.

Dermatofibrosarcoma protuberans (DFSP) is a rare tumor of the dermis layer of the skin, and is classified as a sarcoma. There is only about one case per million per year. DFSP is a fibrosarcoma, more precisely a cutaneous soft tissue sarcoma. In many respects, the disease behaves as a benign tumor, but in 2–5% of cases it can metastasize, so it should be considered to have malignant potential. It occurs most often in adults in their thirties; it has been described congenitally, in children, and the elderly. It accounts for approximately 2–6% of soft tissue sarcoma cancers.

Neoplasm Abnormal mass of tissue as a result of abnormal growth or division of cells

A neoplasm is a type of abnormal and excessive growth, called neoplasia, of tissue. The growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and it persists growing abnormally, even if the original trigger is removed. This abnormal growth usually forms a mass. When it forms a mass, it may be called a tumor.

Chondroma cell type benign neoplasm that is a cartilaginous tumor encapsulated with a lobular growing pattern

A chondroma is a benign cartilaginous tumor, which is encapsulated with a lobular growing pattern.

Papilloma cell type benign neoplasm that is composed of epithelial tissue on papillae of vascularized connective tissue

A papilloma is a benign epithelial tumor growing exophytically in nipple-like and often finger-like fronds. In this context, papilla refers to the projection created by the tumor, not a tumor on an already existing papilla.

Neuroma nervous system benign neoplasm that is characterized as a nerve tissue tumor

A neuroma is a growth or tumor of nerve tissue. Neuromas tend to be benign ; many nerve tumors, including those that are commonly malignant, are nowadays referred to by other terms.

Adenomyoma is a tumor (-oma) including components derived from glands (adeno-) and muscle (-my-). It is a type of complex and mixed tumor.

A monokine is a type of cytokine produced primarily by monocytes and macrophages.

Adrenocortical adenoma adrenal adenoma that is a benign tumor of the adrenal cortex

An adrenocortical adenoma is a benign tumor of the adrenal cortex. It can present with Cushing's syndrome or primary aldosteronism. They may also secrete androgens, causing hyperandrogenism. Also, they are often diagnosed incidentally as incidentalomas.

Embryoma is a mass of rapidly growing cells believed to originate in embryonic (fetal) tissue. Embryonal tumors may be benign or malignant, and include neuroblastomas and Wilms tumors. Also called embryoma. Embryomas have been defined as: "Adult neoplasms expressing one or more embryo-exclusive genes."

Foster–Kennedy syndrome Human disease

Foster Kennedy syndrome is a constellation of findings associated with tumors of the frontal lobe.

A Mixed tumor is a tumor that derives from multiple tissue types.

Medulloepithelioma Human disease

Medulloepithelioma is a rare, primitive, fast-growing brain tumour thought to stem from cells of the embryonic medullary cavity. Tumours originating in the ciliary body of the eye are referred to as embryonal medulloepitheliomas, or diktyomas.

Emma Louise Call (1847–1937) was an American physician, and one of the first female physicians in the United States. Along with Sigmund Exner, she is one of the namesakes of Call-Exner bodies, a pathognomonic feature of granulosa cell tumors. These tumors are associated with ovarian cancers.

Vulvar tumors are those neoplasms of the vulva. Vulvar and vaginal neoplasms make up a small percentage (3%) of female genital cancers. They can be benign or malignant. Vulvar neoplasms are divided into cystic or solid lesions and other mixed types. Vulvar cancers are those malignant neoplasms that originate from vulvar epithelium, while vulvar sarcomas develop from non-epithelial cells such as bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue. Epithelial and mesenchymal tissue are the origin of vulvar tumors.

References

  1. "mixed tumor - definition of mixed tumor in the Medical dictionary - by the Free Online Medical Dictionary, Thesaurus and Encyclopedia" . Retrieved 2007-12-15.
Classification
D