Related Research Articles
Rab27 is a member of the Rab subfamily of GTPases. Rab27 is post translationally modified by the addition of two geranylgeranyl groups on the two C-terminal cysteines.
There are three bone morphogenetic protein receptors in humans:
CD98 is a glycoprotein that is a heterodimer composed of SLC3A2 and SLC7A5 that forms the large neutral amino acid transporter (LAT1). LAT1 is a heterodimeric membrane transport protein that preferentially transports branched-chain and aromatic amino acids. LAT is highly expressed in brain capillaries relative to other tissues.
Two Melanin-concentrating hormone receptors (MCHR) have recently been characterized: MCH-R1 and MCH-R2. These two receptors share approximately 38% homology.
ERM transcription factor is a transcription factor generated in Sertoli cells, which are found in the testes and play a crucial role in spermatogenesis.
The Rev-ErbA proteins are members of the nuclear receptor family of intracellular transcription factors. There are two forms of the receptor, alpha and beta, each encoded by a separate gene.
The testicular receptor proteins are members of the nuclear receptor family of intracellular transcription factors. There are two forms of the receptor, TR2 and TR4, each encode by a separate gene.
The chicken ovalbumin upstream promoter transcription factor (COUP-TFs) proteins are members of the nuclear receptor family of intracellular transcription factors. There are two variants of the COUP-TFs, labeled as COUP-TFI and COUP-TFII encoded by the NR2F1 and NR2F2 genes respectively.
SH3BP2 is a protein that comes from a gene located on Chromosome 4. SH3BP2 binds differentially to the SH3 domains of certain proteins of signal transduction pathways. It binds to phosphatidylinositols linking the hemopoietic tyrosine kinase fes to the cytoplasmic membrane in a phosphorylation dependent mechanism. It is also associated with cherubism.
The EGF module-containing Mucin-like hormone Receptors (EMRs) are closely related subgroup of G protein-coupled receptors (GPCRs). These receptors have a unique hybrid structure in which an extracellular epidermal growth factor (EGF)-like domain is fused to a GPCR domain through a mucin-like stalk. There are four variants of EMR labeled 1-4, each encoded by a separate gene. These receptors are predominantly expressed in cells of the immune system and bind ligands such as CD55.
The prokineticin receptor is a G protein-coupled receptor which binds the peptide hormone prokineticin. There are two variants each encoded by a different gene. These receptors mediate gastrointestinal smooth muscle contraction and angiogenesis.
The free fatty acid receptor is a G-protein coupled receptor which binds free fatty acids. There are four variants of the receptor, each encoded by a separate gene. Preliminary findings suggest that FFAR2 and FFAR3 may interact to form a FFAR2-FFAR3 receptor heteromer.
The Retinoic Acid-Inducible orphan G-protein-coupled receptors (RAIG) are a group of four closely related G protein-coupled receptors whose expression is induced by retinoic acid.
The neuropeptide B/W receptors are members of the G-protein coupled receptor superfamily of integral membrane proteins which bind the neuropeptides B and W. These receptors are predominantly expressed in the CNS and have a number of functions including regulation of the secretion of cortisol.
Zinc finger protein 3 is a protein that in humans is encoded by the ZNF3 gene.
Brain-specific angiogenesis inhibitors are G-protein coupled receptors belonging to the class B secretin subfamily. Members include:
Potassium voltage-gated channel subfamily G member 2 is a protein that in humans is encoded by the KCNG2 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.
Potassium voltage-gated channel subfamily H member 3 is a protein that in humans is encoded by the KCNH3 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.
Potassium voltage-gated channel subfamily H member 4 is a protein that in humans is encoded by the KCNH4 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.
Pol refers to a gene in retroviruses, or the protein produced by that gene.
