1,3-Propanedisulfonic acid

1,3-Propanedisulfonic acid
Names
	Preferred IUPAC name Propane-1,3-disulfonic acid
	Other names Eprosidate
Identifiers
CAS Number	21668-77-9 ;
3D model (JSmol)	Interactive image ;
ChEMBL	ChEMBL2111092 ;
ChemSpider	379112 ;
ECHA InfoCard	100.204.148
PubChem CID	428573 ;
UNII	6QFP76V7S7 ;
CompTox Dashboard (EPA)	DTXSID4048301 ;
	InChI InChI=1S/C3H8O6S2/c4-10(5,6)2-1-3-11(7,8)9/h1-3H2,(H,4,5,6)(H,7,8,9) Key: MGNVWUDMMXZUDI-UHFFFAOYSA-N;
	SMILES C(CS(=O)(=O)O)CS(=O)(=O)O;
Properties
Chemical formula	C3H8O6S2
Molar mass	204.21 g·mol−1
Melting point	120–125 °C (248–257 °F; 393–398 K)
Boiling point	157 °C (315 °F; 430 K)
Hazards
	GHS labelling:
Pictograms
Signal word	Danger
Hazard statements	H302, H312, H314, H332
Precautionary statements	P260, P261, P264, P270, P271, P280, P301+P312, P301+P330+P331, P302+P352, P303+P361+P353, P304+P312, P304+P340, P305+P351+P338, P310, P312, P321, P322, P330, P363, P405, P501
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Last updated June 08, 2025

1,3-Propanedisulfonic acid is a sulfonic acid containing two sulfonate units. Its salts are called eprodisates and have been evaluated as a protector of renal function in AA amyloidosis.^[2]

References

1 2 McElvain, S. M.; Jelinek, Arthur; Rorig, Kurt (September 1945). "Ethane-1,2- and Propane-1,3-disulfonic Acids and Anhydrides". Journal of the American Chemical Society. 67 (9): 1578–1581. Bibcode:1945JAChS..67.1578M. doi:10.1021/ja01225a053.
↑ Rumjon, Adam; Coats, Thomas; Javaid, Muhammad M (24 February 2012). "Review of eprodisate for the treatment of renal disease in AA amyloidosis". International Journal of Nephrology and Renovascular Disease . 5: 37–43. doi: 10.2147/IJNRD.S19165 . ISSN 1178-7058. PMC 3304340 . PMID 22427728.

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[thermal-1] 1 2 McElvain, S. M.; Jelinek, Arthur; Rorig, Kurt (September 1945). "Ethane-1,2- and Propane-1,3-disulfonic Acids and Anhydrides". Journal of the American Chemical Society. 67 (9): 1578–1581. Bibcode:1945JAChS..67.1578M. doi:10.1021/ja01225a053.

[2] Rumjon, Adam; Coats, Thomas; Javaid, Muhammad M (24 February 2012). "Review of eprodisate for the treatment of renal disease in AA amyloidosis". International Journal of Nephrology and Renovascular Disease . 5: 37–43. doi: 10.2147/IJNRD.S19165 . ISSN 1178-7058. PMC 3304340 . PMID 22427728.

[1]

[2]

Names

Preferred IUPAC name Propane-1,3-disulfonic acid
Other names Eprosidate
Identifiers
CAS Number	21668-77-9
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL2111092
ChemSpider	379112
ECHA InfoCard	100.204.148
PubChem CID	428573
UNII	6QFP76V7S7
CompTox Dashboard (EPA)	DTXSID4048301
InChI InChI=1S/C3H8O6S2/c4-10(5,6)2-1-3-11(7,8)9/h1-3H2,(H,4,5,6)(H,7,8,9) Key: MGNVWUDMMXZUDI-UHFFFAOYSA-N
SMILES C(CS(=O)(=O)O)CS(=O)(=O)O
Properties
Chemical formula	C₃H₈O₆S₂
Molar mass	204.21 g·mol⁻¹
Melting point	120–125 °C (248–257 °F; 393–398 K)^[1]
Boiling point	157 °C (315 °F; 430 K)^[1]
Hazards
GHS labelling:
Pictograms
Signal word	Danger
Hazard statements	H302, H312, H314, H332
Precautionary statements	P260, P261, P264, P270, P271, P280, P301+P312, P301+P330+P331, P302+P352, P303+P361+P353, P304+P312, P304+P340, P305+P351+P338, P310, P312, P321, P322, P330, P363, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

1,3-Propanedisulfonic acid

See also

References